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11.
We report a case of cerebral dural sinus thrombosis presenting as acute subarachnoid haemorrhage and clinically mimicking an aneurysmal bleed. Awareness of this rare initial presentation of cerebral venous thrombosis is important and should be considered in the diagnostic work‐up of acute subarachnoid haemorrhage. The radiologist plays a crucial role in making this often unsuspected but important diagnosis to enable prompt appropriate treatment. 相似文献
12.
Wu DC; Liu JM; Chen YM; Yang S; Liu SM; Chen LT; Whang-Peng J 《Japanese journal of clinical oncology》1997,27(2):115-118
Hemolytic uremic syndrome spontaneously arises in a few patients with
advanced cancer, but it is more commonly related to the use of certain
chemotherapeutic agents. Mitomycin-C is, etiologically, the most common
causative agent inducing hemolytic uremic syndrome, in a dose dependent
manner. We report this syndrome, attributable to mitomycin-C at a
cumulative dose of 40 mg/m2, in a gastric cancer patient. A 42-year-old
female with stage III gastric cancer underwent radical gastrectomy and was
given mitomycin-C at 10 mg/m2 intravenously every four weeks as adjuvant
therapy. Hemolytic uremic syndrome was diagnosed three months after the
last dose of mitomycin-C administration. The most prominent symptoms
included pallor, hypertension and anasarca, with laboratory evidence of
microangiopathic hemolytic anemia, azotemia and hyperkalemia. Her disease
was progressive, but fortunately stabilized after staphylococcus column A
dialysis. Her disease remained in remission for 24 months from the time of
diagnosis, and then relapsed in the form of peritoneal carcinomatosis with
partial intestinal obstruction.
相似文献
13.
Prevalence and aetiology of neurological impairment in extremely low birthweight infants 总被引:2,自引:0,他引:2
J WAUGH MJ O'CALLAGHAN DI TUDEHOPE HA MOHAY YR BURNS PH GRAY YM ROGERS 《Journal of paediatrics and child health》1996,32(2):120-124
Objective : To determine the prevalence and perinatal predictors of cerebral palsy, intellectual impairment, visual impairment and deafness in a cohort of extremely low birthweight (ELBW) infants at two years of age.
Methodology : The study population comprised 199 of the 224 (89%) ELBW infants managed at the Mater's Mothers Hospital, Brisbane, between July 1977 and February 1990 and who survived to two years. The prevalence of cerebral palsy, intellectual impairment, blindness and deafness was measured by clinical, psychometric and audiological assessment and the association with 24 risk factors examined.
Results : Cerebral palsy occurred in 20 children (10%). Risk of cerebral palsy was associated with ventricular dilatation, intraventricular haemorrhage, necrotizing enterocolitis and multiple birth, though only ventricular dilatation (OR 4.41; 95% Cl 1.32-14.8) remained significant in the adjusted analysis. Intellectual impairment occurred in 20 children (10%) and was independently associated with ventricular dilatation (OR 15.0; 95% Cl 2.2-102.8), ventilation Fi O2 >80% (OR 3.4; 95% Cl 1.01-11.5), vaginal delivery (OR 3.5; 95% Cl 1.09-11.4) and male sex (OR 6.1; 95% Cl 1.67-22.3). No perinatal predictor was statistically associated with risk of deafness. Retinopathy of prematurity (OR 36.9; 95% Cl 2.8-495.5) was associated with risk of later visual impairment.
Conclusions : Intellectual impairment was associated with a broad range of perinatal variables. Cerebral palsy was associated with fewer variables, all of which were also associated with intellectual impairment. Neurologic injury was associated with male sex and multiple birth, which are not biological insults themselves, but may be markers of susceptibility to injury. 相似文献
Methodology : The study population comprised 199 of the 224 (89%) ELBW infants managed at the Mater's Mothers Hospital, Brisbane, between July 1977 and February 1990 and who survived to two years. The prevalence of cerebral palsy, intellectual impairment, blindness and deafness was measured by clinical, psychometric and audiological assessment and the association with 24 risk factors examined.
Results : Cerebral palsy occurred in 20 children (10%). Risk of cerebral palsy was associated with ventricular dilatation, intraventricular haemorrhage, necrotizing enterocolitis and multiple birth, though only ventricular dilatation (OR 4.41; 95% Cl 1.32-14.8) remained significant in the adjusted analysis. Intellectual impairment occurred in 20 children (10%) and was independently associated with ventricular dilatation (OR 15.0; 95% Cl 2.2-102.8), ventilation F
Conclusions : Intellectual impairment was associated with a broad range of perinatal variables. Cerebral palsy was associated with fewer variables, all of which were also associated with intellectual impairment. Neurologic injury was associated with male sex and multiple birth, which are not biological insults themselves, but may be markers of susceptibility to injury. 相似文献
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套管针连续臂丛阻滞行断指(肢)再植手术35例 总被引:4,自引:1,他引:3
0 引言 臂丛阻滞是上肢手术常用的麻醉方法[1].但这种阻滞方法作用时间短,对于较长时间的上肢手术,因反复穿刺而造成局部损伤较大,神经损伤率增高,患者痛苦增加.断指(肢)再植手术[1]是上肢手术中时间较长者,要求阻滞作用完善.为探讨一种阻滞时间灵活、损伤小、作用确切的麻醉方法,我们受连续硬膜外麻醉的启发[1],摸索出连续臂丛阻滞方法,现介绍如下.1 对象和方法1.1 对象 急诊断指(肢)再植手术35(男28,女7)例,年龄18岁~47岁,均因锐器伤而造成指体离断和上肢远端离断,其中1指离断5例,… 相似文献
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去氢紫堇碱对兔血小板TXB2及主动脉6-keto-PGF1PGF1α含量的影响 总被引:1,自引:0,他引:1
Dehydrocorydaline (DHC) was shown to reduce the production of thromboxane B2 (TXB2)in platelets and 6-keto-prostaglandin F1α (6-keto-PGF1α in the aorta of rabbits in vitro. The effect of DHC increased with the increase of dose.DHC 0.41 mg was found to inhibit the formatiom of TXB2 markedly while not reduce the content of 6-keto-FCF1α. DHC also exhibited obvious inhibitory effect on the arachidonic acid (0.66mmol/L) induced formation of platelet malondialdehyde (MDA). These effects were similiar to the specific cycloxygenase inhibitor, aspirin (0.03 mg/ml). The results suggest that (1) DHC reduced both contents of TXA2 and PGI2 in vitro. (2) DHC markedly inhibited the system of cycloxygenase in cell microsomes. (3) As to whether TXA2 synthetase or cycloxygenase was inhibited in these experiments is still to be elucidated. 相似文献
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