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101.
目的 观察家兔面神经急性损伤后髓鞘和轴索的组织病理变化。方法 用丝线结扎茎乳孔以外的面神经总干 ,观察结扎后 1天、3天及 5天面神经的组织病理改变。结果 家兔面神经受损后 ,先后在髓鞘和轴索出现轻重不等、程度不同的形态学改变。结论 结扎家兔面神经后 ,其髓鞘及轴索会出现相应的病理改变 ,且随着结扎天数的增加 ,面神经损伤亦呈加重的趋势 相似文献
102.
Li Chunjing Guo Liwen Luo Mi Guo Mingjuan Li Jierong Zhang Shilin Liu Guoqing 《International urology and nephrology》2021,53(10):1987-1993
International Urology and Nephrology - Ureteroscopy is widely applied in pregnant women with renal colic, but such patients are easy to experience uterine contraction after surgery. There are many... 相似文献
103.
Chun-xia Tian Ming-yue Li Xin-xin Shuai Feng Jiang Ya-lan Dong Yang Gui Zi-li Zhang Ren-jie Qin Zhen-yu Kang Lan Lin Alexey Sarapultsev Bin Wu Shan-shan Luo De-sheng Hu 《Phytotherapy research : PTR》2023,37(1):50-61
Myocardial infarction (MI) is one of the diseases with high fatality rate. Berberine (BBR) is a monomer compound with various biological functions. And some studies have confirmed that BBR plays an important role in alleviating cardiomyocyte injury after MI. However, the specific mechanism is unclear. In this study, we induced a model of MI by ligation of the left anterior descending coronary artery and we surprisingly found that BBR significantly improved ventricular remodeling, with a minor inflammatory and oxidative stress injury, and stronger angiogenesis. Moreover, BBR inhibited the secretion of Wnt5a/β-catenin pathway in macrophages after MI, thus promoting the differentiation of macrophages into M2 type. In summary, BBR effectively improved cardiac function of mice after MI, and the potential protective mechanism was associated with the regulation of inflammatory responses and the inhibition of macrophage Wnt5a/β-catenin pathway in the infarcted heart tissues. Importantly, these findings supported BBR as an effective cardioprotective drug after MI. 相似文献
104.
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106.
James F. Markmann Michael R. Rickels Thomas L. Eggerman Nancy D. Bridges David E. Lafontant Julie Qidwai Eric Foster William R. Clarke Malek Kamoun Rodolfo Alejandro Melena D. Bellin Kathryn Chaloner Christine W. Czarniecki Julia S. Goldstein Bernhard J. Hering Lawrence G. Hunsicker Dixon B. Kaufman Olle Korsgren Christian P. Larsen Xunrong Luo Ali Naji José Oberholzer Andrew M. Posselt Camillo Ricordi Peter A. Senior A. M. James Shapiro Peter G. Stock Nicole A. Turgeon 《American journal of transplantation》2021,21(4):1477-1492
107.
108.
Yu Hongjuan Zeng Xueyun Sui Mingjie Liu Rui Tan Rachel Lee-Yin Yang Jinjin Huang Weidong Luo Nan 《Quality of life research》2021,30(3):855-866
Quality of Life Research - This study aimed to compare the measurement properties of EQ-5D-3L(3L) and EQ-5D-5L(5L) in patients with acute myeloid leukemia (AML) in China. We consecutively recruited... 相似文献
109.
桥粒斑蛋白II(DPII)是一种新的上皮和上皮性肿瘤标记物。我们应用针对石蜡切片的抗DPII单抗和抗细胞角蛋白(CK)单抗对2l7例肿瘤作了免疫组织化学ABC法染色的研究,结果:在163例上皮性肿瘤和双向分化的肿瘤中,147例表达DPII,占90.7%,92例表达CK,占56.4%。CK阳性染色全部位于细胞浆内,DPII阳性染色则同时分布在细胞交界面上和细胞浆中。其他54例不含桥粒的肿瘤均无DPII和CK表达。结果表明,DPII单抗是有用的含桥粒肿瘤的免疫组化探针。因DPII不存在于一切含桥粒肿瘤,故在鉴别上皮性肿瘤时,DPII单抗尚需与其他上皮标记物的抗体合并使用。 相似文献
110.
Following crush injury to rat sciatic nerves, a crude fraction of the 150,000 g supernatant can post-translationally incorporate [3H]Arg and [3H]Lys into endogenous proteins in amounts approximately 10 times uninjured control nerves. These increases occur in the proximal nerve stump within 2 h of injury and 2 weeks later in a distal segment of nerve containing the tips of the regenerating axons. In the present experiments, the endogenous nerve proteins modified by Arg or Lys in these nerve segments have been identified using two-dimensional polyacrylamide gel electrophoresis. The fraction used to assay for protein modification, the void volume of a Sephacryl S-300 column, was found to contain only a few proteins visible by Coomassie blue staining, one of which is likely to be albumin (68 kDa, pI 6.4). While this protein was modified by both Arg and Lys, the majority of label was found in areas not showing Coomassie blue staining. This indicates that of the many potential targets of post-translational arginylation and lysylation, most are proteins of relatively low abundance. A variety of proteins were modified by Arg or Lys alone while others were modified by both Arg and Lys. A high molecular weight protein (175 kDa, pI 9.0) was modified only by Lys and only at 2 h post crush. Of a variety of modified proteins of approximately 17 kDa one (pI 6.3) was modified by both Arg and Lys and at both time points, while another (pI 9.0) was modified at both time points, but only by Lys. The results show that Arg and Lys can be added post-translationally to a large number of low abundance, soluble sciatic nerve proteins, and that some of those proteins are modified only by Arg or Lys while others are modified by both Arg and Lys. Also, the modification of certain proteins appears to be associated specifically with the immediate response of a nerve to injury (e.g. 88 kDa, pI 7.1) while others are associated with the regenerative period (e.g. 56 kDa, pI 7.4). 相似文献