New macromonomeric initiators (macroinimers), 2 Gelation in bulk polymerization of styrene with macroinimers

Macroinimers were obtained by the reaction of 4,4′-dicyano-4,4′-azovaleryl chloride (1) , poly(ethylene glycol) and methacryloyl chloride. They were thermally homopolymerized and copolymerized with styrene in bulk (40 wt.-%). Crosslinking increases as polymerization time increases.     

Beneficial effect of immunosuppressive drugs on Parry-Romberg syndrome: a case report and review of the literature

Progressive facial hemiatrophy, also known as Parry-Romberg syndrome (PRS), is characterized by slowly progressive atrophy of one side of the face, primarily involving the subcutaneous tissues and fat. Involvement of the central nervous system with impairment of neurologic function occurs infrequently. At present, there is no agreement as to whether PRS is a distinct entity or a clinical variant of linear scleroderma en coup de sabre. The exact reason for PRS has not yet been determined; therefore, no suitable treatment exists. We observed beneficial effects of immunosuppressive agents on neurologic lesions in particular in a patient with PRS who presented with immunoinflammatory findings and neurologic involvement, apart from cutaneous manifestations.     

Continuous perfusion with morphine of the orbitofrontal cortex reduces allodynia and hyperalgesia in a rat model for mononeuropathy

Recent imaging reports demonstrate the activation of the orbitofrontal cortical (OFC) area during acute and chronic pain. The aim of this study was to compare the effects of chronic perfusion of this area with morphine on nociception in control rats and in rats subjected to mononeuropathy. Chronic perfusion of morphine, using miniosmotic pumps, produced significant and naloxone-reversible depression of tactile and cold allodynias and thermal hyperalgesia, observed in neuropathic rats, while it produced significant elevation and naloxone insensitive increase of acute nociceptive thresholds in control rats. The observed results support the idea that this area is a component of a flexible cerebral network involved in pain processing and perception.     

Intravitreal triamcinolone acetonide for the treatment of cystoid macular edema secondary to Behçet disease

PURPOSE: To evaluate the safety and effectiveness of intravitreal triamcinolone acetonide in patients with cystoid macular edema (CME) associated with Beh?et disease. DESIGN: Interventional case series. METHODS: Ten eyes of 10 patients with CME from Beh?et disease made up the study population. All eyes had persistent CME despite medical treatment for at least 2 months. Intravitreal injection of 4 mg (0.1 ml) of triamcinolone acetonide was offered to treat macular edema. The visual and anatomic responses were observed. RESULTS: At 1-month follow-up, a reduction in mean foveal thickness of 37.4%, from 416 microm to 260.5 microm, was attained. At 3-month follow-up, mean foveal thickness was 286.2 microm and at 6 months, 263.7 microm. No eyes had lost vision at 1 month, and eight eyes (80%) showed improvement in visual acuity. At 3-month and 6-month follow-up, three eyes (30%) remained stable and the other eyes had maintained the improved acuity. CONCLUSION: Intravitreal triamcinolone acetonide is a promising therapeutic method for CME from Beh?et disease.     

Problems pertaining to the long head of the biceps brachii in subacromial impingement syndrome

In this paper, we presented the pathological changes occurring in the long head of the biceps muscle in subacromial impingement syndrome, and evaluated treatment approaches in the light of the relevant data.