Neonatal lupus erythematosus with persistent telangiectasia and spastic paraparesis

A case of neonatal lupus erythematosus with cutaneous and neurological features is reported. At 5 years of age, the patient retains residual telangiectatic lesions over the trunk and face and has mild spastic diplegia, originally detected at the age of 1 year. Persistent telangiectasia is now a recognized feature of neonatal lupus erythematosus. The pathogenesis of the neurological deficit is uncertain.     

Pemphigoid nodularis: a report of two cases

Pemphigoid nodularis is a rare variant of bullous pemphigoid characterized by the development of pruritic hyperkeratotic nodules. These nodules may be the presenting feature of the disease, and may precede the development of bullae by several years. The condition appears to be more common in females than males, and is often resistant to treatment. We report two definite cases and one possible case of pemphigoid nodularis, and review the literature relating to this disorder.     

GROWTH HORMONE DEFICIENCY IN MITOCHONDRIAL CYTOPATHY

ABSTRACT. Two boys with mitochondrial cytopathy, short stature and growth hormone deficiency showed a significant growth response to human growth hormone. Although not all short patients with mitochondrial cytopathy are growth hormone deficient the association of these conditions should be recognised so that the treatable endocrine disorder can be positively excluded.