The Recent Studies on Treatment of the Damaged Intestinal Mucosa

Intestinal mucosa serves as an important defencebarrier of the organism because the damaged mucosamay cause a variety of pathogenic changes.     

奎的平与氯氮平治疗精神分裂症对照研究

目的：探讨奎的平、氯氮平对精神分裂症的疗效及副作用。方法：80例患者随机分为两组，分别应用奎的平或氯氮平治疗6周，采用四级临床疗效评定标准、阳性症状与阴性症状量表(PANSS)、副反应量表(TESS)评定疗效及副反应。结果：奎的平组有效率87．5％，氯氮平组有效率82．5％。治疗第一周末，奎的平组PANSS量表总分较治疗前差异有显著性(P＜0．05)。奎的平组副反应低于氯氮平组。结论：奎的平与氯氮平疗效相似，但奎的平起效较快，副反应较轻。     

胃癌双对比造影表现与血5‘—核苷酸酶相关性的研究

目的　初步探讨胃癌影像学表现与 5′-核苷酸酶 (5′- NT)活性的变化关系。方法　经病理证实的 4 1例胃癌 ,均行 X线双对比造影摄片 ,并采用分光光度法测其治疗前血清 5′- NT活性。以 4 0例健康人作对照组。结果　胃癌组 5′- NT活性 (1.14± 0 .16 u/ ml)较正常健康人明显减低 (2 .6 0± 0 .10 u/ m l) (P<0 .0 5 )。解剖部位上 ,从贲门、胃体到胃窦部胃癌 ,其 5′- NT活性分别为 0 .98、1.2 0、1.2 8u/ m l,呈逐渐升高的趋势。溃疡型胃癌 5′- NT活性(0 .96 u/ ml)低于肿块型 (1.12 u/ m l)和浸润型 (1.4 0 u/ ml)。 期胃癌 5′- NT(1.5 3u/ ml)高于 期 (0 .83u/ m l)、 期 (0 .98u/ ml)和 期 (1.0 3u/ m l) (P<0 .0 5 )。结论　胃癌患者血清 5′- NT活性明显较正常人降低 ,其酶活性的变化与胃癌的形态、生长部位及进展程度有一定的相关     

CT对肝内,外阻塞性黄疸的鉴别诊断价值

笔者通过对３５例阻塞怀黄疸的ＣＴ所见，指出了胆道扩张征象可作为鉴别肝内、阻阻塞性黄疸的可靠指标，再结合临床及ＣＴ的初期征象，可更加提高其鉴别诊断准确率。本文对这些指标的可靠性进行重点讨论。提出了该特点是特别胆道管囊肿的重要指征，即后者的胆道扩张为局部性或节段性。本文对良、恶性病变所致的胆道扩张形态亦进行了对照分析，发现二阻之间无明显性差异。     

Baclofen intoxication: report of four cases and review of the literature.

Four cases of baclofen intoxication are reported, with a review of 33 cases from the literature. Analysis of these 37 cases suggests that there are two types of baclofen intoxication syndrome. Patients with acute intoxication present with four major clinical manifestations: encephalopathy (disturbance of consciousness and/or seizure), respiratory depression, muscular hypotonia, and generalized hyporeflexia. Patients with chronic intoxication present with hallucinosis, impaired memory, catatonia, or acute mania. The acute intoxication syndrome has a faster onset, shorter duration, more severe clinical manifestations, and higher incidence of seizures than the chronic intoxication syndrome. Baclofen intoxication, although it may cause grave encephalopathic manifestations and electroencephalographic findings, has a benign outcome if actively managed.     

红细胞沉降率IV──红细胞沉降速度测量的原理和方法

本文从理论上提出了红细胞沉降速度的准确概念，阐明了红细胞沉降过程所包含的物理和生理信息，提出了一种新型测量红细胞沉降速度及其它特征参数的方法，并给出了其主体、硬件和软件设计要点。     

Spurious hyperchloremia and decreased anion gap in a patient with dextromethorphan bromide.

Although cold syrup containing dextromethorpan bromide is widely administered, the bromism due to cold syrup has not been reported. We report a patient who had negative anion gap with hyperchloremia and conscious loss because of daily intake of cold complex syrup (containing dextromethorphan bromide 0.4 mg/ml, acetaminophen 8.33 mg/ml) for headache for 4-5 years. The bromide content in cold complex syrup resulted in serum levels of bromide that interfered with the automated analyzers for chloride content. When conscious change is due to bromism, hemodialysis instead of forced hydration and diuresis should be performed immediately. Therefore, patients with a markedly negative anion gap with hyperchloremia should be considered as having halide intoxication.     

聚芳醚砜薄膜的气体透过行为

研究了一系列聚芳醚砜的Ｈ２、ＣＯ２、Ｏ２、Ｎ２和ＣＨ４气体透过性能，讨论了其气体透过的温度依赖性。与双酚Ａ聚砜（ＰＳＦ）相比，几种新型聚芳醚砜的气体透过系数和气体选择系数同时有所提高。通过聚合物的分子链段活动性和自由体积数据系列变化，讨论了气体透过速率与分子结构的关系。     

Effects of Nephritis No.3 Recipe on Nitric Oxide,Nitric Oxide Synthase Secreted by Cultured Mesangial Cells in Rats and the Gene Expression of Inducible Nitric Oxide Synthase

Objective:To explore the effect of the Nephritis No.3(N-3)recipe on nitric oxide(NO),nitric oxide synthase(NOS)secreted by cultured mesangial cells(MC)and its gene expression of the in-ducible nitric oxide synthase(iNOS).Methods:The drug(nephritis No.3)-containing serum was preparedwith serum pharmacological technique,and then was applied to react on mesangial cells cultured In fetalcalf serum(FCS)and cells cultured in FCS plus lipopolysaccharide.To observe the secretion of NO andNOS and the gene expression of iNOS by means of RT-PCR.Results:Under the two kinds of culture con-ditions,the content of NO and NOS in the groups with drug-containing serum were higher than thosewithout drug-containing serum(P<0.05,P<0.01),and the expression of iNOS mRNA was up-regula-ted too.Conclusion:The N-3 could significantly promote the secretion of NO and NOS and the mRNA ex-pression of iNOS in rats.