全文获取类型
收费全文 | 2489篇 |
免费 | 168篇 |
国内免费 | 3篇 |
专业分类
耳鼻咽喉 | 16篇 |
儿科学 | 107篇 |
妇产科学 | 147篇 |
基础医学 | 369篇 |
口腔科学 | 142篇 |
临床医学 | 177篇 |
内科学 | 416篇 |
皮肤病学 | 35篇 |
神经病学 | 124篇 |
特种医学 | 36篇 |
外科学 | 395篇 |
综合类 | 43篇 |
一般理论 | 1篇 |
预防医学 | 138篇 |
眼科学 | 122篇 |
药学 | 126篇 |
中国医学 | 15篇 |
肿瘤学 | 251篇 |
出版年
2024年 | 7篇 |
2023年 | 27篇 |
2022年 | 43篇 |
2021年 | 85篇 |
2020年 | 47篇 |
2019年 | 71篇 |
2018年 | 81篇 |
2017年 | 58篇 |
2016年 | 63篇 |
2015年 | 70篇 |
2014年 | 120篇 |
2013年 | 137篇 |
2012年 | 195篇 |
2011年 | 199篇 |
2010年 | 113篇 |
2009年 | 88篇 |
2008年 | 160篇 |
2007年 | 131篇 |
2006年 | 116篇 |
2005年 | 116篇 |
2004年 | 111篇 |
2003年 | 96篇 |
2002年 | 71篇 |
2001年 | 38篇 |
2000年 | 35篇 |
1999年 | 32篇 |
1998年 | 12篇 |
1997年 | 12篇 |
1996年 | 19篇 |
1995年 | 12篇 |
1994年 | 11篇 |
1992年 | 12篇 |
1991年 | 23篇 |
1990年 | 12篇 |
1989年 | 22篇 |
1988年 | 17篇 |
1987年 | 20篇 |
1986年 | 24篇 |
1985年 | 11篇 |
1984年 | 13篇 |
1983年 | 14篇 |
1977年 | 7篇 |
1974年 | 8篇 |
1973年 | 8篇 |
1972年 | 12篇 |
1971年 | 6篇 |
1970年 | 6篇 |
1969年 | 8篇 |
1968年 | 11篇 |
1967年 | 6篇 |
排序方式: 共有2660条查询结果,搜索用时 17 毫秒
51.
Forest Fire Smoke Exposures and Out-of-Hospital Cardiac Arrests in Melbourne,Australia: A Case-Crossover Study 总被引:1,自引:0,他引:1
Martine Dennekamp Lahn D. Straney Bircan Erbas Michael J. Abramson Melita Keywood Karen Smith Malcolm R. Sim Deborah C. Glass Anthony Del Monaco Anjali Haikerwal Andrew M. Tonkin 《Environmental health perspectives》2015,123(10):959-964
Background
Millions of people can potentially be exposed to smoke from forest fires, making this an important public health problem in many countries.Objective
In this study we aimed to measure the association between out-of-hospital cardiac arrest (OHCA) and forest fire smoke exposures in a large city during a severe forest fire season, and estimate the number of excess OHCAs due to the fire smoke.Methods
We investigated the association between particulate matter (PM) and other air pollutants and OHCA using a case-crossover study of adults (≥ 35 years of age) in Melbourne, Australia. Conditional logistic regression models were used to derive estimates of the percent change in the rate of OHCA associated with an interquartile range (IQR) increase in exposure. From July 2006 through June 2007, OHCA data were collected from the Victorian Ambulance Cardiac Arrest Registry. Hourly air pollution concentrations and meteorological data were obtained from a central monitoring site.Results
There were 2,046 OHCAs with presumed cardiac etiology during our study period. Among men during the fire season, greater increases in OHCA were observed with IQR increases in the 48-hr lagged PM with diameter ≤ 2.5 μm (PM2.5) (8.05%; 95% CI: 2.30, 14.13%; IQR = 6.1 μg/m3) or ≤ 10 μm (PM10) (11.1%; 95% CI: 1.55, 21.48%; IQR = 13.7 μg/m3) and carbon monoxide (35.7%; 95% CI: 8.98, 68.92%; IQR = 0.3 ppm). There was no significant association between the rate of OHCA and air pollutants among women. One hundred seventy-four “fire-hours” (i.e., hours in which Melbourne’s air quality was affected by forest fire smoke) were identified during 12 days of the 2006/2007 fire season, and 23.9 (95% CI: 3.1, 40.2) excess OHCAs were estimated to occur due to elevations in PM2.5 during these fire-hours.Conclusions
This study found an association between exposure to forest fire smoke and an increase in the rate of OHCA. These findings have implications for public health messages to raise community awareness and for planning of emergency services during forest fire seasons.Citation
Dennekamp M, Straney LD, Erbas B, Abramson MJ, Keywood M, Smith K, Sim MR, Glass DC, Del Monaco A, Haikerwal A, Tonkin AM. 2015. Forest fire smoke exposures and out-of-hospital cardiac arrests in Melbourne, Australia: a case-crossover study. Environ Health Perspect 123:959–964; http://dx.doi.org/10.1289/ehp.1408436 相似文献52.
53.
Kane Jeremy C. Sharma Anjali Murray Laura K. Chander Geetanjali Kanguya Tukiya Skavenski Stephanie Chitambi Chipo Lasater Molly E. Paul Ravi Cropsey Karen Inoue Sachi Bosomprah Samuel Danielson Carla Kmett Chipungu Jenala Simenda Francis Vinikoor Michael J. 《AIDS and behavior》2022,26(2):523-536
AIDS and Behavior - This randomized controlled trial tested the efficacy of a multi-session, evidence-based, lay counselor-delivered transdiagnostic therapy, the Common Elements Treatment Approach... 相似文献
54.
Deepanker Tewari Fabio Del Piero Stephen Cieply Willard Feria Helen Acland 《Journal of virological methods》2013
Equine herpesvirus-1 (EHV-1) strains with a single point mutation at the 2254 nucleotide position with a G2254 constitution within the DNA polymerase gene are associated strongly with equine myeloencephalopathies. Infections with non-neuropathogenic EHV-1 strains without the G2254 nucleotide but with an A2254 nucleotide are associated less frequently with equine neurologic disease. A retrospective study utilizing DNA extracted from formalin fixed paraffin embedded tissues was conducted with real time PCR and pyrosequencing, to determine the infecting EHV-1 strains. Infection with EHV-1 A2254 and or G2254 strain was detected with real time PCR, and was confirmed with a rapid pyrosequencing technique. Pyrosequencing was useful in at least 2 cases where real time PCR was equivocal in determining the infecting EHV-1 strain type. The strain with G2254 mutation was detected in 9.4% of 21 studied abortion cases, and in 86.6% of 15 neurologic cases. 相似文献
55.
Linda Broer Veryan Codd Dale R Nyholt Joris Deelen Massimo Mangino Gonneke Willemsen Eva Albrecht Najaf Amin Marian Beekman Eco J C de Geus Anjali Henders Christopher P Nelson Claire J Steves Margie J Wright Anton J M de Craen Aaron Isaacs Mary Matthews Alireza Moayyeri Grant W Montgomery Ben A Oostra Jacqueline M Vink Tim D Spector P Eline Slagboom Nicholas G Martin Nilesh J Samani Cornelia M van Duijn Dorret I Boomsma 《European journal of human genetics : EJHG》2013,21(10):1163-1168
Telomere length (TL) has been associated with aging and mortality, but individual differences are also influenced by genetic factors, with previous studies reporting heritability estimates ranging from 34 to 82%. Here we investigate the heritability, mode of inheritance and the influence of parental age at birth on TL in six large, independent cohort studies with a total of 19 713 participants. The meta-analysis estimate of TL heritability was 0.70 (95% CI 0.64–0.76) and is based on a pattern of results that is highly similar for twins and other family members. We observed a stronger mother–offspring (r=0.42; P-value=3.60 × 10−61) than father–offspring correlation (r=0.33; P-value=7.01 × 10−5), and a significant positive association with paternal age at offspring birth (β=0.005; P-value=7.01 × 10−5). Interestingly, a significant and quite substantial correlation in TL between spouses (r=0.25; P-value=2.82 × 10−30) was seen, which appeared stronger in older spouse pairs (mean age ≥55 years; r=0.31; P-value=4.27 × 10−23) than in younger pairs (mean age<55 years; r=0.20; P-value=3.24 × 10−10). In summary, we find a high and very consistent heritability estimate for TL, evidence for a maternal inheritance component and a positive association with paternal age. 相似文献
56.
57.
58.
External influence is essential for any change to occur in this world. Similarly, the reaction path of a chemical reaction can be changed with the addition of a catalyst from outside. Sometimes a catalyst performs better when it remains associated with an inert substance, which is called a support material (SM). Improved catalyst accomplishment arises from the ‘proximity effect’. Even inert supports play a role in better product formulation or environmental remediation. In this review, it has been shown how the SM, as a nest, aids the catalyst particle synergistically to perform a good job in a chemical reaction. The structure–function relationship of SM helps in catalyst activation to some extent, and produces active centres that are difficult to fully ascertain. In the text, Langmuir–Hinshelwood (L–H), Mars-van Krevelen (MVK), and Eley–Rideal (E–R) mechanisms are highlighted for the adsorption processes as the case may be. Again, the importance of SM for both catalyst and substrates has been consolidated here in the text. Finally, the role of the initiator and the promoter is also discussed in this review.Catalysts are empowered with proper support materials (SM). The proximity effect, in other word ‘synergism’ between the two, is still necessary to be explored at the molecular level to revamp this never ending field of catalysis. 相似文献
59.
Jerina Tewari Pravash Ranjan Mishra Sujit Kumar Tripathy 《Indian Journal of Orthopaedics》2015,49(5):549-553
Background:
Many authors have reported the anatomical variation of abductor pollicis longus (APL) around the wrist and its association with de Quervain tenosynovitis (DQT), first carpo-metacarpal arthritis, and trapezio-metacarpal subluxation. From Indian subcontinent, there is only one original article and a few case reports on the variability of APL tendon insertion.Materials and Methods:
Fifty formaldehyde preserved cadaveric wrists were dissected to look for the anatomical variation of APL in the Indian population.Results:
The APL was found with single tendon in 2, double in 31, triple in 8, and quadruple in 8 extremities. A maximum of 6 tendon-slips were found in one cadaveric wrist. In all hands, the APL had at least one attachment to first metacarpal bone and in 46 hands (92%), there was second insertion to the trapezium bone. Of all tendon-slips of APL (n = 126), 44% of tendons (68 tendons) were inserted into the base of the first metacarpal bone. This was followed by the insertion into the trapezium in 42% tendons (52 tendons).Conclusion:
Bi-tendinous APL is commonly observed on the dorsal compartment of the wrist in Indian population and these tendon-slips are commonly attached to the first metacarpal base and trapezium. This variation must be understood by the Indian Orthopedic surgeons as the response to treatment of DQT and reason for first carpo-metacarpal arthritis can be dependent on this anatomical variation. 相似文献60.
Durable engraftment and correction of hematological abnormalities in children with congenital amegakaryocytic thrombocytopenia following myeloablative umbilical cord blood transplantation
下载免费PDF全文
![点击此处可从《Pediatric transplantation》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Kris M. Mahadeo Priti Tewari Suhag H. Parikh Timothy A. Driscoll Kristin Page Paul L. Martin Joanne Kurtzberg Vinod K. Prasad 《Pediatric transplantation》2015,19(7):753-757
The use of HSCT is the only potentially curative treatment for CAMT, but access is limited by the availability of suitable donors. We report five consecutive patients with CAMT who received MAC and partially HLA‐mismatched, UCBT (unrelated, n = 4). Median times to neutrophil (>500/μL) and platelet (≥20 000 and ≥50 000/μL) engraftment were 19, 57, and 70 days, respectively. Acute GvHD, grade II, developed in one patient, who subsequently developed limited chronic GvHD. At median follow‐up of 14 yr, all patients are alive with sustained donor cell engraftment. To our knowledge, this is the largest single‐center series of UCBT for patients with this disease and suggests that UCBT is a successful curative option for patients with CAMT. 相似文献