全文获取类型
收费全文 | 179篇 |
免费 | 8篇 |
国内免费 | 104篇 |
专业分类
儿科学 | 5篇 |
妇产科学 | 1篇 |
基础医学 | 14篇 |
临床医学 | 73篇 |
内科学 | 37篇 |
皮肤病学 | 8篇 |
神经病学 | 3篇 |
特种医学 | 29篇 |
外科学 | 14篇 |
综合类 | 24篇 |
预防医学 | 4篇 |
眼科学 | 3篇 |
药学 | 62篇 |
肿瘤学 | 14篇 |
出版年
2023年 | 1篇 |
2022年 | 1篇 |
2021年 | 2篇 |
2020年 | 2篇 |
2018年 | 3篇 |
2017年 | 1篇 |
2016年 | 1篇 |
2015年 | 3篇 |
2014年 | 1篇 |
2013年 | 9篇 |
2012年 | 1篇 |
2011年 | 2篇 |
2010年 | 2篇 |
2009年 | 8篇 |
2008年 | 5篇 |
2007年 | 67篇 |
2006年 | 7篇 |
2005年 | 23篇 |
2004年 | 2篇 |
2003年 | 3篇 |
2002年 | 6篇 |
2001年 | 9篇 |
2000年 | 9篇 |
1999年 | 7篇 |
1998年 | 13篇 |
1997年 | 23篇 |
1996年 | 12篇 |
1995年 | 8篇 |
1994年 | 6篇 |
1993年 | 7篇 |
1992年 | 6篇 |
1991年 | 4篇 |
1990年 | 5篇 |
1989年 | 13篇 |
1988年 | 7篇 |
1987年 | 4篇 |
1985年 | 4篇 |
1984年 | 2篇 |
1983年 | 1篇 |
1980年 | 1篇 |
排序方式: 共有291条查询结果,搜索用时 15 毫秒
51.
The reliability and validity of the pain items of the Hong Kong version interRAI community health assessment for community‐dwelling elders in Hong Kong 下载免费PDF全文
Justina YW Liu PhD RN Iris Chi DSW Kin‐Sun Chan PhD Claudia KY Lai PhD RN Angela YM Leung PhD RN 《Journal of clinical nursing》2015,24(15-16):2352-2354
52.
Srinivasan Sanjay MRCSEd Hui Yee Neo MBBS Tiakumzuk Sangtam MRCSEd Jae Yee Ku MBChB Shirley YM Chau Dip Abdul Karim Rostihar Kah-Guan Au Eong FRCSEd 《Clinical & experimental ophthalmology》2009,37(8):795-800
Purpose: To assess the awareness of age-related macular degeneration (AMD) and its risk factors among Singapore residents.
Methods: A cross-sectional questionnaire-based telephone survey was conducted to ascertain the awareness of AMD with regards to knowledge of the disease entity and possible risk factors among Singapore residents. A Singapore residential telephone directory was used to identify potential households by choosing the first and last entries on randomly selected pages. Respondents included individuals from households with landline telephone connection who were willing to participate in the study after a brief introduction about the study. Verbal consent was sought before proceeding with the interview. Interpreters were used for respondents whose ability to converse in English was limited. Prior to commencement of the study, the protocol was reviewed and approved by Ethics committee of the Domain Specific Review Board.
Results: The interviewers contacted 796 subjects from different households, of which 520 participated (response rate, 65.3%). The age of the respondents ranged from 18 to 85 (median 41) years. Only 38 (7.3%) of them were aware of AMD, the majority of whom had completed secondary or higher education. Two hundred (38.5%) and 191 (36.7%) of the respondents considered age and smoking, respectively, to be risk factors for AMD.
Conclusions: The awareness of AMD among Singapore residents is low. AMD awareness needs to be improved by educational programmes designed for this specific purpose. 相似文献
Methods: A cross-sectional questionnaire-based telephone survey was conducted to ascertain the awareness of AMD with regards to knowledge of the disease entity and possible risk factors among Singapore residents. A Singapore residential telephone directory was used to identify potential households by choosing the first and last entries on randomly selected pages. Respondents included individuals from households with landline telephone connection who were willing to participate in the study after a brief introduction about the study. Verbal consent was sought before proceeding with the interview. Interpreters were used for respondents whose ability to converse in English was limited. Prior to commencement of the study, the protocol was reviewed and approved by Ethics committee of the Domain Specific Review Board.
Results: The interviewers contacted 796 subjects from different households, of which 520 participated (response rate, 65.3%). The age of the respondents ranged from 18 to 85 (median 41) years. Only 38 (7.3%) of them were aware of AMD, the majority of whom had completed secondary or higher education. Two hundred (38.5%) and 191 (36.7%) of the respondents considered age and smoking, respectively, to be risk factors for AMD.
Conclusions: The awareness of AMD among Singapore residents is low. AMD awareness needs to be improved by educational programmes designed for this specific purpose. 相似文献
53.
双波长比值光谱法测定银黄口服液中绿原酸和黄芩苷含量 总被引:6,自引:0,他引:6
目的:应用双波长比值光谱法对银黄口服液中绿原酸和黄芩苷含量测定进行研究。方法:依据绿原酸和黄芩苷的比值光谱特征,选择266和342nm作为测定波长。结果:绿原酸线性范围2-20ug/ml,回收率98。9,RSD为1.58%;黄芩苷线性范围2-16ug/ml,回收率100.4%,RSD为1.32%,结论:本法为一种灵敏,准确和简便的分析方法,可在其他中药制剂中推广应用。 相似文献
54.
无环鸟苷亲脂性前体药物脂质体的制备及体外抗病毒活性(英文) 总被引:2,自引:0,他引:2
本文通过将无环鸟苷(acyclovir,简称ACV)2’位羟基分别与月桂酰氯或棕榈酰氯进行酯化反应,制得亲脂性前体药物无环鸟苷月桂酸酯和无环鸟苷棕榈酸酯(分别简称为C12-ACV和C16-ACV),使脂质体包封率从ACV的29.9%提高到C12-ACV的95.6%和C16-ACV的97.1%;漏泄实验表明在4℃透析60h后,一半以上的ACV从脂质体中漏泄,而C12-ACV和C16-ACV的滞留率分别为70%和80%;体外抗疱疹病毒的试验中,在最低试验浓度0.044μmol/L时,ACV不显示抗病毒活性,而C16-ACV脂质体抑制细胞病变率达75%,说明前体药物通过与脂质体脂膜的结合增加了药物的进入细胞能力,从而提高了ACV的抗病毒能力。 相似文献
55.
Development of hatching blastocysts from immature human oocytes following in-vitro maturation and fertilization using a co-culture system 总被引:8,自引:0,他引:8
Hwu YM; Lee RK; Chen CP; Su JT; Chen YW; Lin SP 《Human reproduction (Oxford, England)》1998,13(7):1916-1921
Recently, in-vitro maturation (IVM) of immature human oocytes recovered
from non-stimulated follicles has been applied in the treatment of
infertility. However, in previous reports, very few embryos cultured in
conventional medium have reached the expanded blastocyst stage following
in-vitro maturation and fertilization (IVM/IVF). The objective of this
study was to investigate whether the developmental competence of human
embryos following IVM/IVF could be enhanced by the use of a human ampullary
cell co-culture system. Immature human oocytes were aspirated from small
follicles at Caesarean section and then cultured in medium containing human
menopausal gonadotrophin for 36 to 48 h, followed by insemination. Zygotes
were randomly cultured either in conventional culture medium alone or in
the co-culture system. Of 48 embryos cultured in conventional medium alone,
all arrested at the 2-16- cell stage on day 3 after insemination. Of 46
embryos cultured in the co-culture system, 26 embryos (56.5%) arrested at
the 2-16-cell stage. Six embryos (13%) developed to the morula stage.
Fourteen embryos (30.4%) developed to expanded blastocysts and two
blastocysts were hatching on day 7 after insemination. We conclude that
co-culture significantly enhances the development of blastocysts in embryos
resulting from IVM/IVF.
相似文献
56.
Multiphasic examinations of 153 gastric abnormalities observed radiologically and endoscopically were reviewed to determine the efficacy of four radiologic techniques and of several common combinations of these techniques for examining the stomach. There were 68 gastric ulcers, 12 ulcer scars, 44 cases of gastritis including 27 with erosions, 24 benign neoplasms, and five malignancies. Double-contrast, compression, mucosal relief, and full-column techniques detected 82%, 65%, 62%, and 51%, respectively, of all lesions diagnosed with the complete multiphasic examinations. Results indicate that the greater the number of techniques employed, the more accurate the examination, with biphasic and multiphasic examinations detecting 9%-18% more lesions overall than simple single- or double-contrast studies. 相似文献
57.
58.
59.
硝基甘油对狗缺血区冠脉循环的作用 总被引:1,自引:0,他引:1
用实验性犬冠脉狭窄模型,冠脉内恒流灌注硝基甘油0.5μg/kg.min-1,使冠脉血流量(CBF)增加、远端小动脉压(DCP)、冠脉血管总阻力(RT)、小冠脉血管阻力(RS)及冠状静脉低切血粘(ηb)减少;而主动脉压和心率无明显变化。恒流灌注硝基甘油1μg/kg.min-1时,在开始5min内冠脉循环的变化同上,并伴大冠脉血管阻力(RL)减少,10 min后出现CBF减少和RT,RL及ηb增加。结果提示,硝基甘油有缓解和加重心肌缺血的双重作用,其作用可能与剂量张扩张远端小动脉压的程度有关。 相似文献
60.