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81.
Erhan OL Bestas A Gursu F Alpay N Ozer AB Gulcu F 《Methods and findings in experimental and clinical pharmacology》2006,28(8):523-526
Intravenous regional anesthesia (IVRA) is a technique whereby a tourniquet is used to restrict blood flow to an exsanguinated limb. Propofol was shown to attenuate ischemia-reperfusion damage. We aimed to investigate the effect of low-dose propofol as an antioxidant in this process. Twenty-six unpremedicated adult patients (ASA I-II) were studied. The patients in the control group (Group C, n = 12) were administered 40 ml of 0.5% lidocaine, while the patients in the propofol group (Group P, n = 14) were administered 40 ml of 0.5% lidocaine plus 20 mg propofol for IVRA. Serum levels of malondialdehyde (MDA) and paraoxonase activity were measured at 1 min before, immediately upon, and 30 min after the release of the tourniquet. Serum paraoxonase activity was observed to have a significant decreasing course in both groups (p < 0.01). In contrast, we observed a progressive increase in the serum levels of MDA in Group C (p < 0.05). However, in Group P, serum levels of MDA after the release of the tourniquet periods were significantly lower than that before the release of the tourniquet (p < 0.05). The addition of propofol (20 mg) to lidocaine for IVRA inhibits MDA levels. We conclude that the addition of propofol to lidocaine can be considered as a useful antioxidant in this type of anesthesia. 相似文献
82.
Introduction: Pyelonephritis-induced renal scarring in children is a major predisposing factor for proteinuria, hypertension, and ultimate
renal failure. The aim of this study was to investigate and compare the efficacy of Tc99m dimercaptosuccinic acid (Tc-DMSA)
renal scintigraphy and renal ultrasonography (USG) in detecting renal scars in children with primary vesicoureteral reflux
(VUR). Materials and methods: Tc-DMSA scan and USG studies were done in 62 children who were admitted to our clinic between 1997 and 2003 because of documented
urinary tract infection (UTI) and diagnosed with primary VUR. Renal scarring detection rates of Tc-DMSA scan and USG were
compared according to reflux grades. Results: In the whole group, renal scars were detected by Tc-DMSA scan and USG in 55% and 38% of refluxing units, respectively. Detection
rates of Tc-DMSA and USG according to reflux grades were as follows: 47% and 29 % in low-grade VUR (grades 1 and 2), 46 %
and 25% in mid-grade VUR (grade 3), 76% and 65% in high-grade VUR (grades 4 and 5), respectively. Conclusion: USG was found to be an inappropriate study in the detection of renal parenchymal scars, irrespective of the reflux grade.
In this study, Tc-DMSA scan detected scars in 35% of kidneys reported to be normal on USG. 相似文献
83.
Gürlek A Celik M Fariz A Ersöz-Oztürk A Eren AT Tenekeci G 《Aesthetic plastic surgery》2006,30(1):34-41
The concept and technique of using high-density porous polyethylene (HDPP), a nonresorbable synthetic material, for nasal
spreader grafts, are presented. This material is thought to be particularly useful in revision (secondary or tertiary) rhinoplasty,
in which internal valve collapse frequently is confronted and septal cartilage often is unavailable because it has been harvested
for spreader or other grafts. Sold as a thin plain sheet (0.85 × 38 × 50 mm) that can be cut to an appropriate size for spreader
grafts, HDPP is a ready-to-use material commercially available on the market. Because HDPP permits ingrowths of fibrous tissue
inside and around, it is a nonabsorbable material that stabilizes the upper lateral cartilages in their new position and maintains
the appropriate internal valve angle. The authors used this material for 15 patients undergoing secondary (n = 12) and tertiary (n = 3) rhinoplasty because of valvular collapse. During the mean follow-up period of 16 months (range, 8–30 months), neither
complication nor recurrence of airway obstruction occurred.
Presented as a free paper at the 4th National Aesthetic Plastic Surgery Meeting of the Turkish Republic of Northern Cyprus,
22–26 June 2005, Kyrenia, TRNC 相似文献
84.
A double-blind, randomized trial with placebo control was planned to evaluate the effects of corticosteroids (betamethasone,
dexamethasone, methylprednisolone) in approximately equivalent doses (8 mg dexamethasone/day), and to compare their effects
with that of tenoxicam, an antiinflammatory drug, on both the edema and ecchymosis in open rhinoplasty with osteotomies. For
this study, 40 patients were divided randomly into five groups of 8 patients each, which received, respectively, betamethasone
(group 1), dexamethasone (group 2), methylprednisolone (group 3), tenoxicam (group 4), and placebo (group 5). Open rhinoplasty
with osteotomies was performed by the same surgeon with the patient under general anesthesia. Drugs were administered just
before the induction of anesthesia and continued for 3 days. Only acetaminophen was used to control postoperative analgesia.
Digital photographs of each patient were taken on postoperative days 1, 3, and 7. Scoring was performed separately for eyelid
swelling and ecchymosis by three observers independently using a graded scale from 0 to 4. No statistically significant differences
existed among the five groups in terms of age, sex, duration of surgery, amount of bleeding, and intravenous fluid administration
during the surgery. On postoperative days 1, 3, and 7, no differences in the levels of ecchymosis or edema among the steroid
groups, the tenoxicam group, and the control groups were observed. In conclusion, the authors observed no significant differences
among the different kinds of steroids administered in equivalent doses (8 mg dexamethasone/day). Steroids used in these doses
were not effective in preventing or reducing edema and ecchymosis after open rhinoplasty with osteotomies. Tenoxicam also
was not effective. No complications caused by the use of steroids were observed during the 6-month follow-up period. 相似文献
85.
Synchronous endometrial and cervical tumors in a 26-year-old nullipara: diagnostic modalities updated 总被引:1,自引:0,他引:1
Hascalik S Celik O Erdem G Usta U Alkan A Karakas HM Mizrak B 《Gynecologic and obstetric investigation》2005,60(3):171-176
Proton magnetic resonance spectroscopy (MRS), performed on conventional magnetic resonance imaging (MRI) scanners, provides useful information at the biochemical level. MRS has been used to measure tissue concentrations of proton-containing compounds such as organic and amino acids, and sugars in living tissues. We have used MRS in a 26-year-old female with suspected cervical and endometrial carcinomas. With the use of the above mentioned technique, biochemical differences in the endometrium and the cervix tissues were detected. The presented case is the first virgin patient in the relevant literature in whom endometrial and cervical carcinoma was detected. Choline (Cho), creatine (Cr), N-acetylaspartate (NAA), lipid and lactate region of the MRS spectrum suggested that the technique could be used as an indicator of metabolic alterations in the cervical and endometrial tumor cells. 相似文献
86.
ObjectiveThe role of magnetic resonance imaging (MRI) in detecting occult spinal dysraphism (OSD) in children with voiding dysfunction and a normal neurological examination is still under debate. The aim of this study was to assess the correlation of sacral skin lesions with OSD detected on MRI, in a population of children with resistant lower urinary tract symptoms (LUTS).Patients and methodsA total of 114 children over 5 years of age with urinary tract infection (UTI) and/or LUTS and normal neurological examination were enrolled. All children underwent sacral neurological examination, urine analysis and cultures, renal/bladder ultrasound, voiding cystourethrogram and urodynamic examination. After a treatment period of 6 months, the patients were re-evaluated and spinal MRI was performed in 61 with ongoing LUTS or UTI.ResultsNineteen of 61 children (31%) had cutaneous stigmas. MRI detected spinal abnormality in 2/42 children with a normal sacral examination in comparison to 7/19 children with an abnormal sacral finding (Chi-squared test, P < 0.005). The sensitivity and specificity of an abnormal sacral finding in predicting MRI abnormality were 0.76 and 0.77, respectively. Urodynamic parameters did not predict an abnormal spinal MRI.ConclusionsAbnormal sacral findings, but not urodynamic studies, are strong predictors of OSD. A normal sacral examination does not rule out OSD. 相似文献
87.
Objective
The Psychopathy Checklist Revised (PCL-R) and Temperament and Character Inventory (TCI) have been used extensively in research of personality disorders; however, no previous study has investigated the relation between psychopathy factors and temperament and character traits in patients with antisocial personality disorder (ASPD). Our aim was to fill this gap in the literature.Methods
The PCL-R Factor scores and the TCI temperament and character scores were evaluated in 68 men with ASPD and 65 healthy male controls.Results
The ASPD cases had significantly higher PCL-R Factor 1, Factor 2, and Total scores, as well as significantly higher TCI Novelty Seeking and Harm Avoidance scores, whereas the control group had higher TCI Reward Dependence, Persistence, Self-Directedness, and Cooperativeness scores. Correlation analysis revealed that, in the whole study group, PCL-R Factor 1, Factor 2, and Total scores were positively correlated with Novelty Seeking and Harm Avoidance scores and negatively correlated with Reward Dependence, Persistence, Self-Directedness, and Cooperativeness scores. When each group was analyzed separately, the correlations were not significant. Regression analysis supported the main findings.Conclusion
Our results showed that both PCL-R Factor 1 score, which is claimed to reflect “core psychopathy,” and PCL-R Factor 2 score, which reflects criminal behaviors, were positively correlated with Novelty Seeking and Harm Avoidance and were negatively correlated with Reward Dependence in the whole sample. The reduced variance of PCL-R in each group might lead to nonsignificant associations within groups. Without the subjects with severe psychopathy in the present study, it might not be possible to show the association. 相似文献88.
Demir B Gursu S Ozturk K Yildirim T Konya MN Er T 《Archives of orthopaedic and trauma surgery》2011,131(9):1195-1201
Background
We are reporting the results of single-stage treatment for patients with forearm deformity and radial head luxation due to hereditary multiple exostosis using distraction osteogenesis. 相似文献89.
Objective
The aim of our study was to investigate the value of choline in the discrimination of benign and malignant soft tissue and bone tumors.Materials and methods
The study group consisted of thirty subjects with bone or soft tissue tumors larger than 1.5 cm in diameter. The experiments were performed in a 1.5 T MR scanner. Coils were selected according to specific locations. A single-voxel MRS was performed for three different TE (time to echo) (31, 136, 272 ms). The volume of interest was positioned on the brightest enhancement. The presence of a cholin peak on at least 2 of these spectrums was considered as the marker of malignancy. The sensitivity, specificity and accuracy of the MRS in the detection and diagnosis of malignant lesions were calculated. The reproducibility of MRS and histopathological results were tested with kappa statistics.Results
Histopathologically, 18 (60%) of the lesions were classed as malignant whereas 12 (40%) were classed as benign. With MRS, 15 (50%) of these lesions were classed as malignant and 15 (50%) as benign. Two patients who were found spectroscopically to have malignant tumors were shown histopathologically to have benign types. Five patients with an MRS showing a benign type were classed with malignant types in histopathological examinations. MRS had a sensitivity rate of 72.2%, specificity of 83.3%, and an accuracy rate of 76.6% in detecting malignant bone and soft tissue tumors. The interrater reliability of both techniques had a kappa value of 0.533.Conclusions
MRS may help in the differentiation of benign and malignant soft tissue and bone tumors. 相似文献90.
We report a 17-year-old adolescent with diagnosis of the coarctation of aorta (CoA) underwent stent implantation in which complicated with non expansion and longitudinal compression of the stent. 相似文献