The effect on the liver of a semiconductor IR laser with a constant magnetic field

Comparative appraisal of the effect of repeated percutaneous action of semiconductor IR-laser, magnetic field, and a combination of these two factors on the liver showed metabolic changes to be sharply manifest in the first 10 days after exposure to the different variants of action. After 20 irradiation sessions the metabolic changes were less manifest and became stabilized in subsequent irradiation of the animals, which may probably be attributed to certain adaptation of the hepatic tissue to the prolonged effect of the factor. The distinguishing feature of the magnetic-laser effect was an increase of the main substrates of energy metabolism (glucose and lipids) and a stable malonic dialdehyde content with a predominant tendency towards neutralization of free-radical reactions. All this justifies the experimental substantiation of the necessity of using a semiconductor IR-laser with a constant magnetic field for correcting metabolic disorders associated with hepatic insufficiency.     

Osteogenic sarcoma and androgens

Endocrinologic examination of 320 male patients with primary osteogenic sarcoma reveals predominance of hyperandrogenemia characterized by decreased levels of sex hormonebinding globulin, elevated testosterone concentration, and increased free androgen index. The occurrence of androgen receptors was similar in the cytosolic fraction of osteogenic sarcoma (56%), benign tumors and tumor-like bone lesions (50%), while their content was higher in osteogenic sarcoma, implying an unfavorable prognosis of metastasizing. Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 122 No. 9, pp. 305–310, September, 1996