全文获取类型
收费全文 | 4935237篇 |
免费 | 389011篇 |
国内免费 | 15589篇 |
专业分类
耳鼻咽喉 | 69183篇 |
儿科学 | 158180篇 |
妇产科学 | 130109篇 |
基础医学 | 741187篇 |
口腔科学 | 137207篇 |
临床医学 | 454315篇 |
内科学 | 901770篇 |
皮肤病学 | 117090篇 |
神经病学 | 413685篇 |
特种医学 | 193486篇 |
外国民族医学 | 968篇 |
外科学 | 740363篇 |
综合类 | 138979篇 |
现状与发展 | 24篇 |
一般理论 | 2809篇 |
预防医学 | 413118篇 |
眼科学 | 115808篇 |
药学 | 351855篇 |
26篇 | |
中国医学 | 12984篇 |
肿瘤学 | 246691篇 |
出版年
2021年 | 56871篇 |
2019年 | 59323篇 |
2018年 | 76152篇 |
2017年 | 58400篇 |
2016年 | 64773篇 |
2015年 | 77246篇 |
2014年 | 111699篇 |
2013年 | 177390篇 |
2012年 | 140247篇 |
2011年 | 148137篇 |
2010年 | 130953篇 |
2009年 | 130966篇 |
2008年 | 133479篇 |
2007年 | 143328篇 |
2006年 | 150906篇 |
2005年 | 145106篇 |
2004年 | 145924篇 |
2003年 | 135778篇 |
2002年 | 124407篇 |
2001年 | 197237篇 |
2000年 | 194197篇 |
1999年 | 174284篇 |
1998年 | 75862篇 |
1997年 | 70578篇 |
1996年 | 68757篇 |
1995年 | 64336篇 |
1994年 | 58176篇 |
1993年 | 54001篇 |
1992年 | 128557篇 |
1991年 | 123373篇 |
1990年 | 118820篇 |
1989年 | 115365篇 |
1988年 | 106257篇 |
1987年 | 104313篇 |
1986年 | 98408篇 |
1985年 | 95818篇 |
1984年 | 77780篇 |
1983年 | 68453篇 |
1982年 | 51624篇 |
1981年 | 47707篇 |
1980年 | 44728篇 |
1979年 | 67685篇 |
1978年 | 53042篇 |
1977年 | 46607篇 |
1976年 | 43238篇 |
1975年 | 44061篇 |
1974年 | 48990篇 |
1973年 | 46928篇 |
1972年 | 43927篇 |
1971年 | 40618篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
941.
Susanne G Warner Adnan A Alseidi Johnny Hong Timothy M Pawlik Rebecca M Minter 《HPB : the official journal of the International Hepato Pancreato Biliary Association》2015,17(9):785-790
BackgroundHepatopancreatobiliary (HPB) surgery fellowship training has multiple paths. Prospective trainees and employers must understand the differences between training pathways. This study examines self-reported fellowship experiences and current scope of practice across three pathways.MethodsAn online survey was disseminated to 654 surgeons. These included active Americas Hepato-Pancreato-Biliary Association (AHPBA) members and recent graduates of HPB, transplant–HPB and HPB–heavy surgical oncology fellowships.ResultsA total of 416 (64%) surgeons responded. Most respondents were male (89%) and most were practising in an academic setting (83%). 290 (70%) respondents underwent formal fellowship training. Although fellowship experiences varied, current practice was largely similar. Minimally invasive surgery (MIS) and ultrasound were the most commonly identified areas of training deficiencies and were, respectively, cited as such by 47% and 34% of HPB-, 49% and 50% of transplant-, and 52% and 25% of surgical oncology-trained respondents. Non-HPB cases performed in current practice included gastrointestinal (GI) and general surgery cases (56% and 49%, respectively) for HPB-trained respondents, transplant and general surgery cases (87% and 21%, respectively) for transplant-trained respondents, and GI surgery and non-HPB surgical oncology cases (70% and 28%, respectively) for surgical oncology-trained respondents.ConclusionsFellowship training in HPB surgery varies by training pathway. Training in MIS and ultrasound is deficient in each pathway. The ultimate scope of non-transplant HPB practice appears similar across training pathways. Thus, training pathway choice is best guided by the training experience desired and non-HPB components of anticipated practice. 相似文献
942.
943.
Characterization of Left Atrial Mechanics in Hypertrophic Cardiomyopathy and Essential Hypertension Using Vector Velocity Imaging
下载免费PDF全文
![点击此处可从《Echocardiography (Mount Kisco, N.Y.)》网站下载免费的PDF全文](/ch/ext_images/free.gif)
944.
About 10% of patients with Lyme disease continue to experience musculoskeletal pain and cognitive dysfunction after recommended antibiotic treatment. This condition is called post-Lyme disease syndrome (PLDS) or post-treatment Lyme disease syndrome. These two terms are used interchangeably. The pathogenesis of PLDS has been controversial. The hypothesis that patients with PLDS may harbor hidden reservoirs of Borrelia burgdorferi after their initial antibiotic treatment is difficult to accept. The prospective, double-blind studies contradict this point of view. Also, recently published research applying xenodiagnosis to PLDS supports the opinion that PLDS most likely has an autoimmune background. Lengthy courses of antibiotics are not justified in patients with PLDS because of the lack of benefit, and they are fraught with hazards. Most patients with PLDS recover from persistent symptoms with time. However, it can take months before they feel completely well. 相似文献
945.
946.
947.
948.
949.
Auda A. Eltahla Fabio Luciani Peter A. White Andrew R. Lloyd Rowena A. Bull 《Viruses》2015,7(10):5206-5224
The hepatitis C virus (HCV) is a pandemic human pathogen posing a substantial health and economic burden in both developing and developed countries. Controlling the spread of HCV through behavioural prevention strategies has met with limited success and vaccine development remains slow. The development of antiviral therapeutic agents has also been challenging, primarily due to the lack of efficient cell culture and animal models for all HCV genotypes, as well as the large genetic diversity between HCV strains. On the other hand, the use of interferon-α-based treatments in combination with the guanosine analogue, ribavirin, achieved limited success, and widespread use of these therapies has been hampered by prevalent side effects. For more than a decade, the HCV RNA-dependent RNA polymerase (RdRp) has been targeted for antiviral development. Direct acting antivirals (DAA) have been identified which bind to one of at least six RdRp inhibitor-binding sites, and are now becoming a mainstay of highly effective and well tolerated antiviral treatment for HCV infection. Here we review the different classes of RdRp inhibitors and their mode of action against HCV. Furthermore, the mechanism of antiviral resistance to each class is described, including naturally occurring resistance-associated variants (RAVs) in different viral strains and genotypes. Finally, we review the impact of these RAVs on treatment outcomes with the newly developed regimens. 相似文献
950.