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排序方式: 共有8410条查询结果,搜索用时 15 毫秒
101.
Isabela Pedroza-Pacheco Alejandro Madrigal Aurore Saudemont 《Cellular & molecular immunology》2013,10(3):222-229
Regulatory T (Treg) cells and natural killer (NK) cells are key players in the immune system. The interaction between these two cell types has been reported to be beneficial in healthy conditions such as pregnancy. However, in the case of certain pathologies such as autoimmune diseases and cancer this interaction can become detrimental, as Treg cells have been described to suppress NK cells and in particular to impair NK cell effector functions. This review aims to discuss the recent information on the interaction between Treg cells and NK cells under healthy and pathologic conditions, to describe the specific conditions in which this interaction takes place, the effect of Treg cells on hematopoietic stem cell differentiation and the consequences of this interaction on the optimization of immunotherapeutic protocols. 相似文献
102.
Gonzalo J. Martínez Martín Valdebenito Alejandro Martínez Sanjay Patel 《The Canadian journal of cardiology》2018,34(10):1370.e1-1370.e3
A 68-year-old man with previous coronary artery bypass surgery presented with acute onset chest pain. After ruling out an acute coronary syndrome, a computed tomography scan demonstrated a giant aneurysm (10 cm × 8 cm) of the right coronary artery saphenous vein graft (SVG) with signs of rupture into the mediastinum. An Amplatzer Vascular Plug II was successfully deployed at the proximal anastomosis of the SVG, achieving complete exclusion. At 6-month follow-up the patient remained asymptomatic and a computed tomography scan confirmed adequate position of the device. Amplatzer Vascular Plug II is a reasonable alternative for SVG aneurysm closure, providing the vein graft supplies nonviable myocardium. 相似文献
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Jeovany Martínez-Mesa David Alejandro González-Chica Jo?o Luiz Bastos Renan Rangel Bonamigo Rodrigo Pereira Duquia 《Anais brasileiros de dermatologia》2014,89(4):609-615
The importance of estimating sample sizes is rarely understood by researchers,
when planning a study. This paper aims to highlight the centrality of sample
size estimations in health research. Examples that help in understanding the
basic concepts involved in their calculation are presented. The scenarios
covered are based more on the epidemiological reasoning and less on mathematical
formulae. Proper calculation of the number of participants in a study diminishes
the likelihood of errors, which are often associated with adverse consequences
in terms of economic, ethical and health aspects. 相似文献
107.
Julia Carracedo Paula Buendía Ana Merino Sagrario Soriano Elvira Esquivias Alejandro Martín-Malo Pedro Aljama Rafael Ramírez 《Experimental gerontology》2013
Renal dysfunction is closely associated with endothelial damage leading to cardiovascular disease. However, the extent to which endothelial damage induced by uremia is modulated by aging is poorly known. Aging can render endothelial cells more susceptible to apoptosis through an oxidative stress-dependent pathway. We examined whether senescence-associated to oxidative stress determines the injury induced by the uremia in endothelial cells. 相似文献
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José L. Sierra-Sánchez Amparo Martínez-González Fernando García-Sala Bonmatí José F. Ma?es-Ferrer Alejandro Brotons-Oliver 《Medicina oral, patología oral y cirugía bucal》2014,19(1):e74-e81
Objective: To evaluate the predictability of narrow-diameter implants as a treatment option in routine clinical practice. A literature review was performed of studies reporting clinical results obtained with these implants. Survival rates, peri-implant bone loss and related complications were evaluated. The working hypothesis was that narrow-diameter implants offer clinical results similar to those obtained with implants of greater diameter.
Material and Methods: A Medline-PubMed search covering the period between 2002 and 2012 was carried out. Studies published in English and with a follow-up period of at least 12 months were considered for inclusion. A manual search was also conducted in different journals with an important impact factor.
Results: Twenty-one studies meeting the screening criteria were included in the literature review. A total of 2980 narrow-diameter implants placed in 1607 patients were analyzed.
Conclusions: The results obtained from the literature indicate that narrow-diameter implants are a predictable treatment option, since they afford clinical results comparable to those obtained with implants of greater diameter.
Key words:Narrow implant, survival rate, peri-implant bone loss, related complications. 相似文献