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101.
Objective
To assess the prevalence of urinary incontinence (UI) in a group of female athletes and to explore its impact on their lives.Methods
In total, 106 female athletics, basketball, and indoor football athletes were recruited. Data were collected through a questionnaire and a focus group and analyzed via Pearson's χ2 test, 2-way analysis of variance, and thematic analysis.Results
Urinary incontinence was experienced by 41.5% of the athletes. Its prevalence across the 3 types of sport was similar and was not affected by age. However, athletes who experienced UI had a lower body weight (P = 0.011) and a lower body mass index (P = 0.035). Most (95.5%) athletes had never discussed their condition with a health professional. In the focus group, all athletes described preventive urination to avoid urine leakage. It was mentioned that UI affected their performance and made them feel uncomfortable and frustrated.Conclusion
Urinary incontinence is a prevalent condition among athletes that is not openly discussed. However, it causes regular changes in their physical performance and daily life. More research is needed to increase awareness of UI and to design interventions. 相似文献102.
Tam A Krishnamurthy S Pillsbury EP Ensor JE Gupta S Murthy R Ahrar K Wallace MJ Hicks ME Madoff DC 《Journal of vascular and interventional radiology : JVIR》2008,19(1):80-87
PURPOSE: To assess the safety and diagnostic accuracy of percutaneous image-guided splenic biopsy in patients known to have or suspected of having malignancy. MATERIALS AND METHODS: Data from all image-guided splenic biopsies performed at a single institution from January 1992 to March 2007 were retrospectively reviewed. One hundred fifty-six splenic biopsies were performed in 147 patients (78 male and 69 female patients; mean age, 54.9 years; age range, 13-81 years). The most common indications for biopsy were suspected recurrent lymphoma (n = 101, 64.7%), suspected metastatic disease (n = 39, 25%), and unknown diagnosis (n = 16, 10.3%). All biopsies were performed with computed tomographic (n = 86), ultrasonographic (n = 68), or fluoroscopic (n = 2) guidance. Most biopsies (91%) were performed with 22-gauge needles, with a mean of 2.8 passes. The mean lesion size was 3.2 cm (range, 0.8-13 cm). Final diagnosis was confirmed with splenectomy (n = 39), histopathologic correlation with concurrent biopsy or surgical specimen (n = 52), or clinical or imaging follow-up ranging from 2 weeks to 14 years (n = 44). Complications were recorded. RESULTS: Sufficient tissue for pathologic analysis was obtained in 144 of the 156 biopsies (diagnostic yield, 92.3%). The overall sensitivity, specificity, and diagnostic accuracy were 83.4%, 87.8%, and 84.7%, respectively. Complications occurred in 26 biopsies (16.7%), with a 1.9% (n = 3) major complication rate and a 14.7% (n = 23) minor complication rate. Splenectomy was necessary in two patients. CONCLUSIONS: Splenic biopsy in the evaluation of new or recurrent neoplasm is a minimally invasive procedure with low complication rates and a high diagnostic yield. 相似文献
103.
Alda Tam Joe E. Ensor Holly Snyder Sanjay Gupta Jean-Bernard Durand Michael J. Wallace 《Cardiovascular and interventional radiology》2009,32(6):1217-1226
The purpose of this study was to report our clinical experience with image-guided drainage of pericardial effusions in oncology
patients. IRB approval was obtained for this retrospective, HIPAA-compliant study. From November 2002 to January 2008, 40
patients underwent 43 image-guided drainages of pericardial effusions. The medical records were reviewed to analyze the technical
aspects of the procedures, complications, and clinical outcomes. Thirty-three pericardial drains were placed and 10 pericardiocenteses
were performed. The technical success rate was 100%. Thirty-three procedures were performed under computed tomographic (CT)
guidance, five under ultrasound (US) guidance, and five using both CT and US guidance. There were no technical, procedure-related
complications. Delayed postprocedure complications and arrhythmias occurred in 11 cases, for an overall complication rate
of 25.6%. All complications occurred in patients who had undergone drain placement. Nine patients developed new or worsening
arrhythmias and six of these patients required transfer to a higher level of care or the initiation of pharmacological management.
In 58.6% of drain placements, including 4 of 11 patients who developed complications, the catheter could have been removed
earlier. The median overall survival was 6.47 months (95% CI: 2.37, 12.7). In conclusion, image-guided pericardial drain placement
is safe and feasible. Due to the frequency of delayed postprocedure arrhythmias, follow-up monitoring in a telemetry unit
is recommended. Prompt catheter removal after drainage may reduce the incidence of delayed post-catheter-insertion arrhythmias. 相似文献
104.
Merino Hernández M Aranguren Castro J Callén Blecua M Elorz Lambarri J Etxeberria Agirre A Galdiz Iturri JB Irízar Aranburu I Lekue Alkorta I Lizarraga Azparren MA Maeztu López de Alda M Marqués González ML Martínez González A Merino Hernández M Merino Nazábal JM Rotaeche del Campo R Villar Alvarez M;Direccion de Asistencia Sanitaria de Osakidetza-Servicio Vasco de Salud 《Anales de pediatría (Barcelona, Spain : 2003)》2006,64(6):557-572
105.
Tasha Glenn Peter C Whybrow Natalie Rasgon Paul Grof Martin Alda Christopher Baethge Michael Bauer 《Bipolar disorders》2006,8(5P1):424-429
Background: Approximate entropy (ApEn) measures regularity in time series data, while traditional linear statistics measure variability. Using self-reported mood data from patients with bipolar disorder, this preliminary study addressed whether ApEn could distinguish (i) the 60 days prior to the start of a manic or depressed episode from the 60 days prior to a month of euthymia, and (ii) the 60 days prior to a manic episode from the 60 days prior to a depressed episode.
Methods: Self-reported mood data from 49 outpatients with bipolar disorder receiving standard treatment were analysed. The data contained 27 episodes (12 manic and 15 depressed), and 43 periods of 1 month of euthymia. For the 60 days prior to episode or euthymia, the ApEn, linear statistics and the correlation between linear and non-linear measures were calculated.
Results: ApEn was significantly greater in the 60 days prior to a manic or depressive episode than the 60 days prior to a month of euthymia. The onset of an episode was associated with greater irregularity in mood. Variability was also significantly larger and correlated with ApEn. ApEn was significantly greater in the 60 days prior to a manic episode than in the 60 days prior to a depressed episode, whereas measures of variability were not significantly different. Mood in the 60 days prior to mania was more irregular than prior to depression.
Conclusions: Non-linear measures may complement traditional linear measures in the analysis of longitudinal data in bipolar disorder. A larger study is indicated. 相似文献
Methods: Self-reported mood data from 49 outpatients with bipolar disorder receiving standard treatment were analysed. The data contained 27 episodes (12 manic and 15 depressed), and 43 periods of 1 month of euthymia. For the 60 days prior to episode or euthymia, the ApEn, linear statistics and the correlation between linear and non-linear measures were calculated.
Results: ApEn was significantly greater in the 60 days prior to a manic or depressive episode than the 60 days prior to a month of euthymia. The onset of an episode was associated with greater irregularity in mood. Variability was also significantly larger and correlated with ApEn. ApEn was significantly greater in the 60 days prior to a manic episode than in the 60 days prior to a depressed episode, whereas measures of variability were not significantly different. Mood in the 60 days prior to mania was more irregular than prior to depression.
Conclusions: Non-linear measures may complement traditional linear measures in the analysis of longitudinal data in bipolar disorder. A larger study is indicated. 相似文献
106.
Alda R D Sampaio Carlos E A Chagas Thomas P Ong Fernando S Moreno 《Food and chemical toxicology》2007,45(4):563-567
5-Azacytidine is being used for reactivation of tumor suppressor genes. However, its administration during DNA repair pontentiates hepatocarcinogenesis. We observed chemopreventive activities by vitamin A and beta-carotene during early hepatocarcinogenesis. Thus, in the present study we evaluated vitamin A and beta-carotene chemopreventive potential during early hepatocarcinogenesis potentiated by 5-azacytidine. Wistar rats received vitamin A (VAA group), beta-carotene (betaCA group) or corn oil (CO and COA groups). After three weeks of treatment, all animals were initiated with 1,2-dimethylhydrazine. Twelve hours later VAA, betaCA and COA groups received a single dose of 5-Azc. Hepatocytes were selected/promoted by 2-acetylaminofluorene and 70% partial hepatectomy. All animals were sacrificed six weeks after initiation. Compared to CO group (without 5-azacytidine), COA group presented higher (p<0.05) nodule multiplicity, larger (p<0.05) gamma-GT positive lesions that occupied a larger (p<0.05) area of liver section. Compared to COA group, VAA group presented decreased (p<0.05) nodule multiplicity while betaCA group tended to present smaller gamma-GT positive lesions and to decrease occupied liver section. These results reinforce vitamin A and beta-carotene chemopreventive potential. Considering that 5-azacytidine potentiates hepatocarcinogenesis, more studies are needed to elucidate the efficacy and safety of this drug for cancer control. 相似文献
107.
Silveira AM Gazzinelli G Alves-Oliveira LF Bethony J Gazzinelli A Carvalho-Queiroz C Alvarez MC Lima-Silva FC Prata A LoVerde PT Correa-Oliveira R 《Transactions of the Royal Society of Tropical Medicine and Hygiene》2004,98(9):514-519
The effect of the intensity of infection (eggs per gram faeces, epg) on the production of interferon-gamma (INF-gamma), interleukin (IL)-10 and IL-13 by peripheral blood mononuclear cells (PBMCs) from individuals living in a Schistosoma mansoni-endemic area was evaluated. In vitro stimulation of PBMCs with soluble egg antigen (SEA) resulted in significantly higher secretion levels of IFN-gamma in egg-negative individuals compared with those with an intensity of infection of more than 100 epg. In contrast, the egg-positive group produced significantly higher amounts of IL-10. Levels of IL-13 did not differ significantly between egg-positive and egg-negative groups. These findings suggest that IL-10 is an important cytokine in the control of the T helper cell (Th) type 1 responses during human S. mansoni infection, shifting the immune response from Th0 in egg-negative individuals from an endemic area to a Th2 polarization in chronic infected individuals. 相似文献
108.
Inmaculada Insa Pineda Anna Huguet Miguel Marta Chamorro Fernández Marta Espadas Tejerina Cristina Luz Gómez González José A. Alda 《Psychiatry》2020,83(3):231-243
Objective: To evaluate the prevalence of ADHD in a group of parents of children with ADHD compared with the general population. To compare academic level, unemployment aid rate and marital separations/divorce of this parents sample. Methodology: The experimental group was formed by the parents of 60 children with ADHD. The control group was formed by the parents of 60 healthy children. To assess the retrospective and current ADHD symptomatology among the parents of the sample the Wender Utah Rating Scale (WURS) and the Attention Deficit Hyperactivity Disorder-rating scale (ADHD.rs) were used. Also, the Hollingshead Four-Factor Index of Socioeconomic status (SES-Child) was used. Results: 20.33% of the mothers in the case group met criteria for a retrospective diagnosis of ADHD, while none of the control group mothers met criteria (p < .01). Regarding fathers, there was a retrospective ADHD diagnosis in 25% of the case group compared to 10% in the control group (p < .01). In terms of the current symptoms, 25.42% of the mothers and 21.43% of fathers in the case group met diagnostic criteria for probable ADHD compared to 1.67% in the control group (p < .01 in both genders). Parents in the case group had a lower academic level (p < .01), received more unemployment aid (p = .02) and reported a higher rate of marital separation or divorce (p = .02). Conclusions: Parents of children with ADHD have a higher incidence of retrospective and current ADHD diagnosis and they also present worse socioeconomic factors. 相似文献
109.
Superoxide anions produced by inflammatory cells play an important part in the pathogenesis of acid and pepsin induced oesophagitis in rabbits. 总被引:5,自引:0,他引:5 下载免费PDF全文
BACKGROUND: Reactive oxygen metabolites have been associated with gastrointestinal injury. OBJECTIVE: To investigate whether mucosal reactive oxygen metabolites are involved in acid and pepsin induced oesophagitis, and if so, which specific metabolites. METHODS: The effects of free radical scavengers and the anti-inflammatory drug ketotifen on rabbit oesophagitis induced by acidified pepsin were studied. Isolated oesophageal cells were obtained before and after oesophageal injury and the generation of superoxide anion and hydrogen peroxide was analysed by flow cytometry. The presence of inflammatory cells was determined by indirect immunofluorescence with a mouse antirabbit CD11b antibody. RESULTS: Of the free radical scavengers tested, superoxide dismutase, which reacts with the superoxide anion, significantly reduced oesophagitis, whereas catalase, which reacts with hydrogen peroxide, had only a mild effect and dimethylsulphoxide had no effect. Ketotifen significantly reduced the inflammation and also prevented the induction of oesophagitis. Isolated cells obtained from the oesophageal mucosa after acidified pepsin exposure generated increased amounts of superoxide anions, which were mainly produced by CD11b positive cells. CONCLUSIONS: Reactive oxygen metabolites, especially superoxide anion, produced by inflammatory cells play a significant part in the genesis of oesophagitis induced by acid and pepsin in rabbits and might be a target for future medical therapy. 相似文献
110.
Joanna R Santos-Oliveira Carmem BW Giacoia-Gripp Priscilla Alexandrino de Oliveira Valdir S Amato Jose Ângelo L Lindoso Hiro Goto Manoel P Oliveira-Neto Marise S Mattos Beatriz Grinsztejn Mariza G Morgado Alda M Da-Cruz 《BMC infectious diseases》2010,10(1):1-6