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61.
Serkan ?zkul Akif Turna Ahmet Demirkaya Burcu Aksoy Kamil Kaynak 《Journal of thoracic disease》2014,6(12):1731-1735
Background
Chemical pleurodesis can be palliative for recurrent, symptomatic pleural effusions in patients who are not candidate for a thoracic surgical procedure. We hypothesized that effective pleurodesis could be accomplished with a rapid method of pleurodesis as effective as the standard method.Methods
A prospective randomized ‘non-inferiority’ trial was conducted in 96 patients with malignant pleural effusion (MPE) who are not potentially curable and/or not amenable to any other surgical intervention. They were randomly allocated to group 1 (rapid pleurodesis) and to group 2 (standard protocol). In group 1, following complete fluid evacuation, talc slurry was instilled into the pleural space. This was accomplished within 2 h of thoracic catheter insertion, unless the drained fluid was more than 1,500 mL. After clamping the tube for 30 min, the pleural space was drained for 1 h, after which the thoracic catheter was removed. In group 2, talc-slurry was administered when the daily drainage was lower than 300 mL/day.Results
No-complication developed due to talc-slurry in two groups. Complete or partial response was achieved in 35 (87.5%) and 33 (84.6%) patients in group 1 and group 2 respectively (P=0.670). The mean drainage time was 40.7 and 165.2 h in group 1 and group 2 respectively (P<0.001).Conclusions
Rapid pleurodesis with talc slurry is safe and effective and it can be performed in an outpatient basis. 相似文献62.
63.
CATHRIN THEIS M.D. HANKE MOLLNAU M.D. SEBASTIAN SONNENSCHEIN M.D. TORSTEN KONRAD M.D. EWALD HIMMRICH M.D. KARSTEN BOCK M.D. EBERHARD SCHULZ M.D. DENISE KÄMPFNER M.D. SIMON GERHARDT M.D. BLANCA QUESADA OCETE M.D. THOMAS MÜNZEL M.D. THOMAS ROSTOCK M.D. 《Journal of cardiovascular electrophysiology》2014,25(8):889-895
64.
JÜRGEN KUSCHYK M.D. GORAN MILASINOVIC M.D. Ph.D VOLKER KÜHLKAMP M.D. PAUL R. ROBERTS M.D. MARKUS ZABEL M.D. FRANCK MOLIN M.D. STEPHEN SHOROFSKY M.D. Ph.D F.H.R.S. KURT D. STROMBERG M.S. PAUL J. DEGROOT M.S. FRANCIS D. MURGATROYD M.D. SOLO STUDY INVESTIGATORS 《Journal of cardiovascular electrophysiology》2014,25(1):29-35
65.
66.
Possible hazardous effects of hydrofluoric acid and recommendations for treatment approach: a review
Hydrofluoric acid (HF) is commonly used for conditioning the glass ceramics either prior to cementation or for intraoral repair
in prosthetic and restorative dentistry. The present study offers a review of chemical properties of HF used, highlight the
possible hazardous effects of this agent, and to recommend the treatment approach for potential risks. Available published
information documented in PubMed, Medline, and Picarta literature databases was reviewed. Additional information was derived
from scientific reports, medical and chemical textbooks, handbooks, product information, manufacturers’ instructions, Internet
web sites of the HF manufacturers. No report was found on the incidence of the hazardous effects of HF in dentistry. Reports
from other fields presented incidences of acute and chronic symptoms in exposure to HF. While acute symptoms include skin
or nail burns, chronic ones involve systemic toxicity, eye injuries, inhalation and ingestion-related symptoms that can be
even fatal. HF can be harmful and particularly aggressive to soft tissues, but symptoms may not be apparent immediately after
exposure. The hazardous effects are not based on the pH value, but on the toxicity of HF. Potential hazards of HF known from
other applications than dentistry should be considered also in dental applications. Especially the clinicians, who often deal
with adhesive cementation or repair of glass ceramics, should take necessary precautions for possible hazards of HF. 相似文献
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69.
G. Gürleyik E. Gürleyik A. Yilmazcan A. Özcan I. Onaran S. Ünalmiser 《Acta chirurgica Belgica》2013,113(1):33-36
The leakage of colonic anastomoses increases perioperative morbidity significantly. The purpose of the study was to investigate the influence of neurotensin, an intestinal trophic peptide, on the healing of colonic anastomosis. Forty-two Wistar-albino rats were separated into three equal groups: Group 1 (control group) — segmental resection of the left colon and end-to-end anastomosis; Group 2 (dexamethasone group) — resection and anastomosis, plus 0.1 mg/kg/day of dexamethasone; Group 3 (neurotensin group) — same surgical procedure plus 300 pg/kg/day of neurotensin. Bursting pressure and tissue hydroxyproline content were determined as parameters of the anastomosis strength and healing on the 3rd and 7th days postoperatively. On the 3rd day, mean bursting pressures were 141.4, 146.7 and 73.1 (p = 0.0001) cm of water in the control group, dexamethasone and neurotensin groups respectively. On the 7th day, bursting pressures were measured as 237.4, 100.6 (p = 0.0001) and 72.7(p = 10-6) cm of water, in the control group, dexamethasone and neurotensin groups respectively. Between the 3rd and 7th days, bursting pressures were increased significantly in the control group (p = 0.0001), decreased in the dexamethasone (p = 0.048), and maintained their lowest values in the neurotensin (p = 0.96) groups. On the 7th day, mean hydroxyproline levels were measured as 9.20, 3.30 (p = 0.007), 2.86 (p = 0.007) pg, in the control group, dexamethasone, and neurotensin groups respectively. Between the 3rd and 7th days, tissue hydroxyproline levels were increased significantly in the control group (p = 0.004), decreased in the dexamethasone (p = 0.03), and maintained their lowest values in the neurotensin (p = 0.87) groups. The anastomosis resistance to intraluminal pressure was weak, tissue collagen content was insufficient, and healing was inadequate in the dexamethasone and neurotensin groups in respect to the control group. We concluded that neurotensin impaired the healing, and affected the strength of the colonic anastomosis. 相似文献
70.
Ercan Erdogan Mehmet Akkaya Ahmet Bacaksiz Abdurrrahman Tasal Osman S?nmez Mehmet Ali Elbey Seref Kul Mehmet Akif Vatankulu Murat Turfan ?mer G?ktekin 《Clinics (S?o Paulo, Brazil)》2013,68(10):1333-1337