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71.
Angelena M. W. Ho M.B.B.S. Caroline E. Blane M.D. Thomas F. Kling Jr. M.D. 《Skeletal radiology》1986,15(3):224-227
Dysplasia epiphysealis hemimelica can be diagnesed on plain radiographs of the affected areas. However, double contrast arthrography in three new cases provided additional information. The cartilaginous portions of the lesion at the articular surface of the bone were precisely demonstrated, aiding the orthopedic surgeon in deciding which patients should have surgery and planning the extent of operation necessary. 相似文献
72.
The influence of 3 different, preoperatively given glucocorticoids (30 mg/kg bw methylprednisolone, 3 mg/kg bw dexamethasone, 30 mg/kg hydrocortisone) on extravascular lung water (EVLW) was investigated in a randomised study consisting of 60 patients undergoing elective aortocoronary bypass surgery and compared to a control group having received 0.9% NaCl as placebo. EVLW-measurements were performed by using the double indicator dilution technique with indocyanine green and a microprocessed lung water computer. Besides EVLW-measurements haemodynamics and various laboratory data were studied before as well as after (15 min, 45 min, 5 h) extracorporeal circulation (ECC). ECC was followed by an increase in EVLW, which was less pronounced in the dexamethasone-group without being statistically significant (p = 0.1), however. Pulmonary gas exchange, too, did not differ statistically, in spite of a less pronounced (p = 0.1) deterioration of paO2 in the dexamethasone-group. Haemodynamics and laboratory data in the corticoid-group did not show any significant difference compared to the non-treated control group. It was concluded, that pretreatment with corticoids in pharmacological doses in cardiac surgery had no beneficial effects on extravascular lung water and pulmonary function. 相似文献
73.
The influence of different vasopressors (Akrinor, etilefrine, ephedrine, norfenefrine, ameziniummetilsulfate) on arterial perfusion pressure and oxygenator volume during extracorporeal circulation was compared to a control group. All substances led to an increase in perfusion pressure, thus demonstrating a direct influence on arterial vessels. The rise in arterial pressure after injection of ameziniummetilsulfate persisted during the investigation period, whereas norfenefrine led to a short-lasting, but massive increase. No rise in venous tone was noticed during the investigation period. 相似文献
74.
Cyril Gitiaux MD Emmanuel Roze MD PhD Kiyoka Kinugawa MD Constance Flamand‐Rouvière ST Nathalie Boddaert MD PhD Emmanuelle Apartis MD PhD Vassili Valayannopoulos MD Guy Touati MD Jacques Motte MD PhD David Devos MD PhD Karine Mention MD Dries Dobbelaere MD PhD Diana Rodriguez MD PhD Agathe Roubertie MD PhD Brigitte Chabrol MD PhD François Feillet MD PhD Marie Vidailhet MD Nadia Bahi‐Buisson MD PhD 《Movement disorders》2008,23(16):2392-2397
75.
Ferrari Julia Flamm-Horak Agathe Lischka-Lindner Agnes Knoflach Michael Schnabl Stefan Lang Wilfried 《Wiener Medizinische Wochenschrift》2008,158(15):425-428
Wiener Medizinische Wochenschrift - Eine klinische Verschlechterung innerhalb der ersten Stunden bis Tage bei Patienten, die mit einem ischämischen Schlaganfall oder einer TIA stationär... 相似文献
76.
A P Zingas G A Kling E Crotte E Shumaker P M Vazquez 《Journal of computer assisted tomography》1986,10(6):979-982
Nephrogenic adenoma of the urinary bladder is a rare benign tumor. It is generally accepted that the tumor represents metaplasia of the urothelium in response to chronic inflammation or injury. Its CT appearance can be similar to that of carcinoma of the bladder. 相似文献
77.
Agathe Boussaroque Bécaye Fall Marylin Madamet Cheikhou Camara Nicolas Benoit Mansour Fall Aminata Nakoulima Pierre Dionne Kadidiatou Ba Fall Bakary Diatta Yaya Diémé Boubacar Wade Bruno Pradines 《Antimicrobial agents and chemotherapy》2016,60(1):624-627
The kelch 13 (K13) propeller gene is associated with artemisinin resistance. In a previous work, there were no mutations found in 138 Plasmodium falciparum isolates collected in 2012 and 2013 from patients residing in Dakar, Senegal (M. Torrentino-Madamet et al., Malar J 13:472, 2014, http://dx.doi.org/10.1186/1475-2875-13-472). However, the N554H, Q613H, and V637I mutations were identified in the propeller region of K13 in 92 (5.5%) isolates in 2013 and 2014. There were five polymorphisms identified in the Plasmodium/Apicomplexa-specific domain (K123R, N137S, N142NN/NNN, T149S, and K189T/N). 相似文献
78.
79.
Juliana M. Kling Kathy L. MacLaughlin Peter F. Schnatz Carolyn J. Crandall Lisa J. Skinner Cynthia A. Stuenkel Andrew M. Kauntiz Diana L. Bitner Kristin Mara Karla S. Fohmader Hilsaca Stephanie S. Faubion 《Mayo Clinic proceedings. Mayo Clinic》2019,94(2):242-253
Objective
To evaluate the knowledge of and nature of training for menopause management in postgraduate residents.Participants and Methods
A cross-sectional, anonymous survey was e-mailed to trainees at all postgraduate levels in family medicine, internal medicine, and obstetrics and gynecology at US residency programs between January 11, and July 4, 2017. The survey was adapted from an existing instrument and included questions regarding knowledge of hormone therapy (HT) and other menopause management strategies, availability and type of training in menopause medicine, and demographic information.Results
Of the 703 surveys sent, a total of 183 residents representing 20 US residency programs responded (26.0% response rate). Most trainees were between 26 and 30 years of age (133 of 172 [77.3%]), female (114 of 173 [65.9%]), and believed it was important or very important to be trained to manage menopause (165 of 176 [93.8%]). Although most respondents answered some of the menopause competency questions correctly, important gaps were identified. Of 183 participants, 63 (34.4%) indicated they would not offer HT to a symptomatic, newly menopausal woman without contraindications, and only 71 (38.7%) indicated they would prescribe HT until the natural age of menopause to a prematurely menopausal woman. Of 177 respondents, 36 (20.3%) reported not receiving any menopause lectures during residency, and only 12 of 177 (6.8%) reported feeling adequately prepared to manage women experiencing menopause.Conclusion
Family medicine, internal medicine, and obstetrics and gynecology residency trainees recognize the importance of training in menopause management, but important knowledge gaps exist. Investing in the education of future clinicians to provide evidence-based, comprehensive menopause management for the growing population of midlife women is a priority. 相似文献80.
Podzamczer D Ferrer E Gatell JM Niubo J Dalmau D Leon A Knobel H Polo C Iniguez D Ruiz I 《Antiviral therapy》2005,10(1):171-177
OBJECTIVE: To describe the occurrence of a high early virological failure (VF) rate and development of resistance mutations in antiretroviral-naive patients receiving tenofovir, didanosine and efavirenz. METHODS: HIV-infected antiretroviral-naive patients with viral load > or =30 000 copies/ml were enrolled in a pilot randomized trial of tenofovir/didanosine (250 mg)/ efavirenz with (arm A) or without (arm B) lopinavir/r for the first 12 weeks. As six cases of early VF (a drop of <2 log at month 3, or a rebound of >1 log from the nadir) were detected (five in arm B and one in arm A who had previously stopped lopinavir/r) an unplanned interim analysis was performed. RESULTS: A total of 29 out of 36 enrolled patients completed at least 3 months of follow-up and were included in the interim analysis. An intent-to-treat analysis showed treatment failure in 7/15 (46.7%) patients in arm B (five VF, one lost, one switched) versus 2/14 (14.3%) in arm A (one lost, one switched) (P=0.109). The patient in arm A who interrupted lopinavir/r at day 3 and continued with tenofovir/didanosine/efavirenz later developed VF. At baseline, 6/6 VF patients had VL >100000 copies/ml and an advanced stage of disease (CD4 <200 plus CDC stage C or B3) versus 0/8 non-VF patients taking the triple drug regimen (P<0.001). At failure, G190S/E alone or associated with K103N and K101R mutations was detected in five patients, and K103N/L1001/V108l in the sixth patient. Additionally, L74V/I and K65R were detected in four and two patients, respectively. CONCLUSIONS: A high early virological failure rate and the occurrence of resistance mutations were detected in a group of antiretroviral-naive patients treated with tenofovir/didanosine/efavirenz. 相似文献