Chamberless Endodontic Access for Treatment of Calcified Anterior Central Incisors

IntroductionModern techniques for treating maxillary anterior central incisors with calcified canals emphasize maintaining coronal dentin with small crown access. Alternatively, traditional retrograde surgical procedures are focused on creating an apical seal predominately limited to the remaining resected apical one third of the root canal space. A treatment option for calcified anterior teeth, with avoidance of traditional orthograde access, is presented. Chamberless endodontic access (CEA) to the canal is chosen in this case, leveraging a previous surgical treatment and osseous defect to create straight line canal access.MethodsA tooth presenting with a chronic apical abscess and an apparent previous apical surgery was instrumented and obturated using a CEA avoiding the traditional orthograde approach to the root canal system. Straight line approach was achieved retrograde and canal instrumentation was performed using ultrasonic activated U-files. Canal obturation was accomplished with warm vertical condensation technique followed by placement of an apical retroseal.ResultsA successful 52-month outcome demonstrated the viability of CEA facilitating retrograde instrumentation and obturation.ConclusionsUse of CEA simultaneously protected the clinical crown and provided a successful clinical outcome. A viable option for treatment of an anterior calcified canal and abscess due to dental trauma, CEA mitigates many of the risks associated with the treatment of calcified root anatomy.     

Cardiac and Great Vessel Involvement in “Behcet's Disease”

Abstract Behcet's disease is a multisystem disorder and classified as “vasculitic syndrome with a wide variety of clinical manifestations.” Cardiac involvement is very rare but can occur with different presentations including: pericarditis, cardiomyopathy, endocarditis, endomyocardial fibrosis, intracavitary thrombosis, and coronary artery disease. Great vessel involvement is more common. Recurrent Phlebitis, commonly involving large vessels (superior vena cava, inferior vena cava, hepatic veins) and cerebral veins are the sole presentation in this regard. Arterial involvement is expressed by aneurysm or pseudoaneurysmal formation. Due to the wide variety of cardiovascular manifestations and the resulting high mortality, cardiac surgeons should be familiar with this disease. In this paper we review the articles and introduce our four cases presenting with aneurysm of ascending aorta with free aortic insufficiency, aneurysm of descending aorta, pulmonary artery aneurysm, and pseudoaneurysm of aortic arch.     

母胎界面血管内皮生长因子水平在妊娠高血压综合征中的意义

目的:血管内皮生长因子是一种对血管内皮细胞有特异高效的促有丝分裂因子,试验通过检测血管内皮生长因子在母血、脐带血以及胎盘母面和子面的水平,探索妊娠高血压综合征的发病因素和胎儿宫内发育迟缓发生的机制。方法:①试验对象:选取2006-10/2007-03在深圳市沙井医院就诊的正常孕妇及患有妊娠高血压综合征的孕妇各30人分别作为正常孕妇组和妊娠高血压综合征组,均为初产妇,两组孕妇年龄、孕周及体质量差异无显著性。纳入标准:正常孕妇及妊娠高血压综合征孕妇均无其他妊娠合并症或疾患,年龄24～35岁。患者对试验知情同意。②试验方法及评估:取母亲外周静脉血、新生儿脐带血及胎盘母面、子面标本各一块,酶联免疫吸附法检测母血、脐带血、胎盘母面及子面组织匀浆中的血管内皮生长因子含量,免疫组织化学染色及荧光染色观察血管内皮生长因子的表达。实验结果采用Excel2003软件进行两独立样本的t检验和Pearson相关分析。结果:纳入正常孕妇及患有妊娠高血压综合征的孕妇各30人,均进入结果分析。①免疫组织化学染色及荧光染色显示正常产妇胎盘子面内皮生长因子表达强阳性。②酶联免疫吸附结果显示,两组受试者胎盘母面、母血血管内皮生长因子含量差异无显著性(P>0.05);妊娠高血压综合征组胎盘子面、脐带血血管内皮生长因子含量与正常妊娠胎盘子面、脐带血相比较,差异显著(P<0.05)。结论:妊娠高血压综合征患者胎盘子面血管内皮生长因子水平下降,脐带血中血管内皮生长因子水平升高,提示母胎界面的异常可能与妊娠高血压综合征的发生有关。     

Astigmatism among Chinese school children

This study aims to provide information about the prevalence of astigmatism among Chinese school children in Hong Kong, and its relationship with age, sex and corneal toricity. Subjective refraction and corneal curvatures were performed on 383 school children from age six to 17 years. Although there is a high prevalence of myopia among Chinese populations, astigmatism does not seem to follow the same trend. Among school children from age six to 17 years, about 50 per cent suffer from astigmatism. For those with astigmatic errors, both corrected and corneal astigmatism remain constant and low. With-the-rule astigmatism predominates. These results are comparable to the data from Caucasian populations. The relationship between corrected astigmatism and corneal astigmatism also confirmed previous findings. The modified version of Javal's rule suggested by Grosvenor et al¹ would also serve as a good guide in determining the corrected astigmatism for the Chinese group.     

6-甲氧基正丁苯酞在大鼠肝微粒体中的代谢研究

报道了用GC/MS方法及衍生化技术研究6-甲氧基正丁苯酞(MBP)在大鼠肝微粒体中的代谢转化结果。6-甲氧基正丁苯酞在苯巴比妥(PB)诱导的大鼠肝微粒体中主要转化为3-羟基、γ-羟基取代物,6-羟基正丁苯酞与一个环氧化代谢产物。