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F Aydin† C Cokluk‡ N Senturk† K Aydin‡ MT Canturk† AY Turanli† 《Journal of the European Academy of Dermatology and Venereology》2006,20(5):588-590
Stevens-Johnson syndrome (SJS) is a severe cutaneous eruption that most often appears as an adverse reaction to medication. In this report, we present two patients diagnosed with SJS, which developed in patients with brain tumour, after receiving cranial irradiation and phenytoin. Concomitant application of these two therapies may play an important role in the occurrence of the disease. 相似文献
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Harrys A Torres Parag Mahale Ethan D Miller Thein H Oo Catherine Frenette Ahmed O Kaseb 《World journal of hepatology》2013,5(6):332-335
The use of direct-acting antiviral agents (e.g., telaprevir, boceprevir) has improved response rates in patients with hepatitis C virus (HCV) genotype 1 infections. Substantial number of drug-drug interactions are anticipated with the use of telaprevir, a cytochrome P450 3A and P-glycoprotein substrate and inhibitor. Herein we describe a patient with HCV-associated hepatocellular carcinoma treated simultaneously with a telaprevir-containing regimen and localized chemotherapy (transcatheter arterial chemoembolization) with doxorubicin. No clinically relevant interactions or adverse events developed while on antiviral therapy. 相似文献
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Pharmacodynamics of fish oil: protective effects against prostate cancer in TRAMP mice fed with a high fat western diet 下载免费PDF全文
Saw CL Wu TY Paredes-Gonzalez X Khor TO Pung D Kong AN 《Asian Pacific journal of cancer prevention》2011,12(12):3331-3334
Numerous epidemiological studies suggest that frequent consumption of fish would decrease certain major inflammatory-related chronic diseases including cancer. Aims: To investigate the cancer chemoprotective effect of fish oil (FO) in Transgenic Adenocarcinoma of Mouse Prostate (TRAMP) mice fed a FO diet (10% Menhaden fish oil; FO group) versus a 20% high fat diet (HF group; typical of a Western diet), both with a total content of 20% fat and equal calories. Methods: For each diet, two experimental arms were performed. The mice were put on diet at 8th or 12th week of age for periods of 14 and 10 weeks, the experiments being terminated when the mice reached 22 weeks of age. The animals were monitored weekly for health, and upon necropsy were examined for whole body metastasis, and prostate tissues were confirmed with histopathology. Results: At the end of the study, the FO group had significantly reduced prostate tumor weight (p<0.05) compared to the HF group. The incidence of palpable tumors and carcinomas was also lowered. Finally, there was no metastasis found in the FO group, whereas in the HF group, 16.7% of the mice were found to have metastases. Conclusions: This is the first study showing the beneficial effects of FO against prostate cancer having a HF diet, suggesting potential beneficial effects of FO in humans consuming HF in their diet. 相似文献
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Tomoya Hirota Anthony Guerrero Norman Sartorius Daniel Fung Bennett Leventhal Say H. Ong Hitoshi Kaneko Suporn Apinuntavech Abang Bennett Jegannathan Bhoomikumar Keun‐Ah Cheon Oyunsuren Davaasuren Susan Gau Brian Hall Evgeny Koren Tuan van Nguyen Tin Oo Susan Tan Masaru Tateno Manivone Thikeo Tjhin Wiguna Mark Wong Yi Zheng Norbert Skokauskas 《Psychiatry and clinical neurosciences》2019,73(2):84-89
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