全文获取类型
收费全文 | 3455143篇 |
免费 | 248724篇 |
国内免费 | 6110篇 |
专业分类
耳鼻咽喉 | 47161篇 |
儿科学 | 112685篇 |
妇产科学 | 94017篇 |
基础医学 | 499079篇 |
口腔科学 | 98423篇 |
临床医学 | 314266篇 |
内科学 | 665648篇 |
皮肤病学 | 77096篇 |
神经病学 | 272907篇 |
特种医学 | 129266篇 |
外国民族医学 | 693篇 |
外科学 | 518622篇 |
综合类 | 76055篇 |
现状与发展 | 14篇 |
一般理论 | 1256篇 |
预防医学 | 267708篇 |
眼科学 | 82844篇 |
药学 | 255133篇 |
74篇 | |
中国医学 | 7553篇 |
肿瘤学 | 189477篇 |
出版年
2021年 | 27497篇 |
2019年 | 27818篇 |
2018年 | 39084篇 |
2017年 | 29489篇 |
2016年 | 32965篇 |
2015年 | 37215篇 |
2014年 | 52447篇 |
2013年 | 78224篇 |
2012年 | 107920篇 |
2011年 | 114376篇 |
2010年 | 68247篇 |
2009年 | 64030篇 |
2008年 | 106804篇 |
2007年 | 113812篇 |
2006年 | 115067篇 |
2005年 | 111051篇 |
2004年 | 106826篇 |
2003年 | 102396篇 |
2002年 | 98852篇 |
2001年 | 163020篇 |
2000年 | 167359篇 |
1999年 | 140368篇 |
1998年 | 39872篇 |
1997年 | 34857篇 |
1996年 | 35047篇 |
1995年 | 33256篇 |
1994年 | 30573篇 |
1993年 | 28589篇 |
1992年 | 108258篇 |
1991年 | 105221篇 |
1990年 | 101954篇 |
1989年 | 98376篇 |
1988年 | 90213篇 |
1987年 | 88301篇 |
1986年 | 83066篇 |
1985年 | 79490篇 |
1984年 | 59019篇 |
1983年 | 50288篇 |
1982年 | 29368篇 |
1979年 | 53694篇 |
1978年 | 37864篇 |
1977年 | 31797篇 |
1976年 | 30146篇 |
1975年 | 32055篇 |
1974年 | 38834篇 |
1973年 | 37189篇 |
1972年 | 34711篇 |
1971年 | 32638篇 |
1970年 | 30278篇 |
1969年 | 28634篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
71.
Francesco S. Violante 《La Medicina del lavoro》2020,111(4):249
Background:Criteria for diagnosis and compensation of occupational musculoskeletal diseases varies widely between countries as demonstrated by the large differences between countries with comparable economics and social systems (for example, within the European Union). Several countries have a list of occupational diseases and sometimes these lists include diagnostic and attribution criteria, but these criteria are usually not very specific, and they may also be very different.Objectives:The aim of this paper is to explicitly define what are the information needed for an evidence-based diagnosis and attribution of an occupational musculoskeletal disease.Methods:Based on the general framework of evidence-based medicine, a review is presented of the information required to define: - when a musculoskeletal disease is present, according to the best available techniques; - how to define a relevant exposure to biomechanical risk factors, according to the best available techniques.Results:Criteria are presented to combine information regarding the diagnosis of a musculoskeletal disease and exposure to biomechanical risk factors for an evidence-based attribution of the disease to the occupational exposure. The criteria use a probabilistic model that combine epidemiologic and medical findings, workplace exposure assessment, and non-occupational factors evaluation.Discussion:The use of the proposed criteria may improve the process of diagnosis and attribution of an occupational musculoskeletal disease. In addition, it makes possible to associate a probability rank to the attribution and, ultimately, it may improve the overall quality of the decisional process of the occupational physician.Key words: Criteria, occupational disease, musculoskeletal system 相似文献
72.
Manisha Udhnani Megan Perez Liv S. Clasen Elizabeth Adeyemi 《Developmental neuropsychology》2020,45(2):79-93
ABSTRACTLanguage and executive functioning are major impairments in many neurodevelopmental disorders, but little is known about the relations between these constructs, particularly using parent-report. Thus, the current research sought to examine relations between executive function and language in two groups – Down syndrome (DS; n=41; Mage = 11.2) and autism spectrum disorder (ASD; n=91; Mage = 7.7). Results were as follows: in DS, executive function predicted pragmatic, but not structural language after covarying for age, sex, and social functioning; in ASD, executive function predicted both. Findings highlight the interrelatedness of language and executive functioning and may have implications for intervention development. 相似文献
73.
Karen Galta Sørensen Knut Øymar Ingvild Dalen Thomas Halvorsen Ingvild Bruun Mikalsen 《Pediatric allergy and immunology》2020,31(1):57-65
Background
Various trajectories for lung function and bronchial hyper-reactivity (BHR) from early childhood to adulthood are described, including puberty as a period with excessive lung growth. Bronchiolitis in infancy may be associated with increased risk of developing chronic obstructive pulmonary disease, but the development of respiratory patterns during puberty is poorly characterized for these children. We aimed to study the development and trajectories of lung function and BHR from 11 to 18 years of age in children hospitalized for bronchiolitis in infancy.Methods
Infants hospitalized for bronchiolitis at the University Hospitals in Stavanger and Bergen, Norway, during 1997-1998, and an age-matched control group, were included in a longitudinal follow-up study and examined at 11 and 18 years of age with spirometry and methacholine provocation test (MPT). The MPT data were managed as dose-response slope (DRS) in the statistical analyses. Changes in lung function and DRS from 11 to 18 years of age were analyzed by generalized estimating equations, including interaction terms.Results
z-scores for forced vital capacity (FVC), forced expiratory volume in first second (FEV1), FEV1/FVC ratio, and DRS were not different from 11 to 18 years of age in both the post-bronchiolitis and the control group. The trajectories from 11 to 18 years did not differ between the two groups. BHR at age 11 was independently associated with asthma at age 18.Conclusion
Children hospitalized for bronchiolitis had stable predicted lung function and BHR from 11 to 18 years of age. The lung function trajectories were not different from controls.74.
Grete Moth Morten B. Christensen Helle Collatz Christensen Anders H. Carlsen Ingunn S. Riddervold Linda Huibers 《Scandinavian journal of primary health care》2020,38(3):272-280
Abstract
Objective
Demands for out-of-hours primary care (OOH-PC) services are increasing. Many citizens call because of non-urgent health problems. Nevertheless, the patients’ motives for requesting medical help outside office hours remains an understudied area. This study aimed to examine motives for calling OOH-PC services in various age groups. 相似文献75.
Testing association of rare genetic variants with resistance to three common antiseizure medications
Stefan Wolking Claudia Moreau Anne T. Nies Elke Schaeffeler Mark McCormack Pauls Auce Andreja Avbersek Felicitas Becker Martin Krenn Rikke S. Møller Marina Nikanorova Yvonne G. Weber Sarah Weckhuysen Gianpiero L. Cavalleri Norman Delanty Chantal Depondt Michael R. Johnson Bobby P.C. Koeleman Wolfram S. Kunz Anthony G. Marson Josemir W. Sander Graeme J. Sills Pasquale Striano Federico Zara Fritz Zimprich Matthias Schwab Roland Krause Sanjay M. Sisodiya Patrick Cossette Simon L. Girard Holger Lerche EpiPGX Consortium 《Epilepsia》2020,61(4):657-666
76.
Kristen McAlpine Rodney H. Breau Dawn Stacey Christopher Knee Michael A.S. Jewett Philippe D. Violette Patrick O. Richard Ilias Cagiannos Christopher Morash Luke T. Lavalle 《Canadian Urological Association journal》2020,14(12):385
IntroductionShared decision-making incorporates patients’ values and preferences to achieve high-quality decisions. The objective of this study was to develop an acceptable patient decision aid to facilitate shared decision-making for the management of small renal masses (SRMs).MethodsThe International Patient Decision Aids Standards were used to guide an evidence-based development process. Management options included active surveillance, thermal ablation, partial nephrectomy, and radical nephrectomy. A literature review was performed to provide incidence rates for outcomes of each option. Once a prototype was complete, alpha-testing was performed using a 10-question survey to assess acceptability with patients, patient advocates, urologists, and methodological experts. The primary outcome was acceptability of the decision aid.ResultsA novel patient decision aid was created to facilitate shared decision-making for the management of SRMs. Acceptability testing was performed with 20 patients, 10 urologists, two patient advocates, and one methodological expert. Responders indicated the decision aid was appropriate in length (82%, 27/33), well-balanced (82%, 27/33), and had language that was easy to follow (94%, 31/33). All patient responders felt the decision aid would have been helpful during their consultation and would recommend the decision aid for future patients (100%, 20/20). Most urologists reported they intend to use the decision aid (90%, 9/10).ConclusionsA novel patient decision aid was created to facilitate shared decision-making for management of SRMs. This clinical tool was acceptable with patients, patient advocates, and urologists and is freely available at: https://decisionaid.ohri.ca/decaids.html. 相似文献
77.
Debbie I. Craig Monica R. Lininger Heidi A. Wayment Ann H. Huffman 《Research in sports medicine (Print)》2020,28(2):181-193
ABSTRACTWhile research on sport-related concussion has increased dramatically over the past decade, research investigating concussion reporting is in its early stages. The purpose of this project was to assess concussion reporting and work with stakeholders to develop and assess strategies to improve reporting. We used a multi-site, repeated measures design with three NCAA Division I football programs, including 223 athlete participants. A modified community-based participatory research (CBPR) approach was used to develop intervention strategies (Fall 2017 season) with stakeholders designed to increase concussion reporting intentions. Preseason and postseason surveys were administered to determine effectiveness. Main outcome measures included concussion knowledge, intervention effectiveness, and reporting intention measures. For all three programs, concussion knowledge was unrelated to reporting intentions. Two of the three programs implemented the intervention strategies and for these programs there was evidence that the interventions were effective. Specifically, athletes from these two programs perceived more support from coaches about reporting (P< 0.05; t= 2.83), received education more frequently (P< 0.05; t= 2.67), and reported being more likely to report concussion symptoms (P< 0.05; t= 2.14). Our study demonstrates that working with stakeholders to develop site-specific strategies to improve concussion reporting is an effective approach to help improve reporting behaviours. 相似文献
78.
Hedy S. Wald 《Medical teacher》2020,42(7):744-755
AbstractPublic health crises, including pandemics, are associated with significant health risk and concomitant stress, fear, decreased sense of control, and uncertainty. Deleterious impact on both physical and mental health can result, including for healthcare professionals and health professions trainees. Changes in governmental policies and hospital protocols for healthcare professionals as well as disruption of educational formats and requirements for trainees can ensue. Difficult anxiety-provoking realities of public health crises including pandemics which involve caring for many seriously ill patients, moral distress including difficult care decisions, personal health risk, and/or potential risk to one’s family can take a dire toll on the mental health of healthcare professionals at all stages of the professional lifecycle. Educational disruptions can create significant anxiety for trainees about completing requirements and achieving competencies. Within this, coping skills may be challenged and strengths may be elucidated as well. Such crises create an imperative for medical educators to support trainees’ wellbeing through adaptive flexibility for curriculum innovation and culturally sensitive resilience and wellbeing interventions. Strategies (‘tips’) to optimize resilience and wellbeing with an integrative resilience approach of individual, learning environment, and organization/systems factors are presented. 相似文献
79.
80.
Vitamin D can be synthesized in the skin via sunlight exposure as well as ingested through diet. Vitamin D deficiency is currently a major global public health issue, with increasing prevalence in both low and high latitude locations. This cross-sectional analysis aimed to compare the intensity of individual Ultraviolet B radiation levels between women of the same ethnicity living in England and Brazil, respectively; and to investigate the association with circulating 25(OH)D concentrations. We analysed data from 135 Brazilian women (England, n = 56, 51° N; Brazil, n = 79, 16° S) recruited for the D-SOL study (Interaction between Vitamin D Supplementation and Sunlight Exposure in Women Living in Opposite Latitudes). Serum 25(OH)D concentrations were analysed by high performance liquid chromatography tandem mass spectrometry (HPLC-MS), individual UVB radiation via UVB dosimeter badges and dietary intake via 4-day diet diaries. Anthropometric, skin phototype, sociodemographic and lifestyle patterns were also assessed. Mean serum 25(OH)D concentration of England residents was significantly lower than Brazil residents. Daily individual UVB radiation level showed a strong significant positive correlation with serum 25(OH)D concentrations. The required UVB radiation to achieve 75 nmol/L was 2.2 SED and 38.8% of the total variance in 25(OH)D concentrations was explained uniquely by daily individual UVB radiation, after controlling for the influence of age and body mass index. Thus, these results highlight the strong positive association between serum 25(OH)D concentrations and individual UVB radiation and the influence of different individual characteristics and behaviours. Collectively, these factors contribute to meaningful, country-specific, public health strategies and policies for the efficient prevention and treatment of vitamin D inadequacy. 相似文献