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??Ultrasound characteristics of thyroid microcarcinoma PAN Fu-shun*??XIE Xiao-yan??LI Xiao-xi??et al. *Department of Ultrasound, the First Affiliated Hospital of Sun Yat-sun University, Guangzhou 510080,China
Corresponding author??XIE Xiao-yan??E-mail??xxy1992@live.cn
Abstract Objective To investigate the ultrasound characteristics of thyroid microcarcinoma. Methods The ultrasound imaging of thirty-four cases of thyroid microcarcinoma confirmed by surgery and pathology between January 2003 and January 2009 at the First Affiliated Hospital of Sun Yat-sun University was analyzed retrospectively. Results Thirty-two (94.1%) cases were detected as hypo-echo nodules. Twenty-eight (85.3%) cases were with irregular shape. Twenty-six (76.5%) cases were with irregular edges calcification. Blood flow was detected in 7 cases with CDFI and lymph node metastasis was found in 4 cases. Conclusion Hypo-echo nodules, regular shape, irregular edges and calcification are the ultrasound characteristic. Comprehending the characteristics may improve the pre-operation diagnosis efficacy.     

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??Diagnosis and treatment of nonfunctioning islet cell tumors SUN Cheng-Yi, JIANG Jian-Xin. Department of Hepatobiliary Surgery, Affiliated Hospital of Guiyang Medical College, Guiyang 550001, China
Corresponding author: SUN Cheng-Yi, E-mail: chengyisun@medmail.com.cn
Abstract Nonfunctioning islet cell tumors, malignant with a high incidence, onset occult. It is difficult to early diagnosis which mainly based on imaging examination. Ultrasound, CT, MRI can accurately locate the lesions, and can distinguish benign and malignant lesions. When diagnosed, surgical treatment should be actively. According to tumor location, size and benign or malignant tumour, different surgical approach was chosen.     

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??Role of surgery in treatment of recurrent or metastatic gastrointestinal stromal tumor WANG Ya-nong, ZHOU Ye. Department of Gastric and Soft Tissue Surgery, Fudan University Shanghai Cancer Center; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China
Corresponding author: WANG Ya-nong, E-mail: wang_yn_ch@163.com
Abstract Gastrointestinal stromal tumor (GIST) is the most common soft tissue sarcomas of the gastrointestinal tract. With the understanding of the mechanisms of GIST carcinogenesis, tyrosine kinase inhibitors (TKIs) have greatly improved the prognosis of patients with recurrent or metastatic GIST, compared to traditional surgery. However, 5% of complete response and gradually appearance of secondary tumor resistance to TKIs still encourage surgeons to evaluate the effect of TKIs combined with surgery. Surgical cytoreduction in patients with recurrent or metastatic GISTs in era of target therapy is the hot spot. The surgery in highly selected patients who have good response to TKIs should be considered fully in the multidisciplinary treatment.     

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??Ultrasonography in the diagnosis and differential diagnosis of thyroid nodules and evaluation ZHENG Yan-ling, LIU Bao-xian, XIE Xiao-yan, et al. Department of Ultrasound, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou510080, China
Corresponding author??XIE Xiao-yan,E-mail??xxy1992@live.cn
Abstract Thyroid nodule is very common. Ultrasound is the first choice in the evaluation of thyroid nodules. Conventional ultrasound is recommended as the initial evaluation for all patients with known or suspicious thyroid nodules. With the development of ultrasound techniques, contrast-enhanced ultrasound and elastography add a new dimension to ultrasound evaluation of thyroid nodules. Ultrasound-guided fine needle aspiration (FNA) helps differentiate benign nodules from malignancy, which has shown high diagnositic performance.     

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??Recurrent aphthous ulcer is the most common oral mucosal disease. Currently??there is no definitive methods for RAU??so alleviating the symptoms is commonly used as the first choice. Low level laser shining is found to have a significant effect on RAU in local therapy??such as anti-inflammation??promoting wound healing??pain relief and biological stimulation. It is suggested that low level laser therapy??LLLT??can be used as an alternative traditional medicine in the world.     

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??Teeth fractures include crown fracture?? root fracture and crown-root fracture. If the tooth fragment is available?? it can be bonded to the tooth. In young patients with immature?? still developing teeth?? it is advantageous to preserve pulp vitality by pulp capping or partial pulpotomy. Also?? this treatment is the choice in young patients with completely formed teeth. If displaced?? reposition the coronal segment of the tooth as soon as possible. As an emergency treatment a temporary stabilization of the loose segment to adjacent teeth can be performed. Sequential therapy for traumatized teeth with mid-root fracture or cervical third fracture or crown-root fracture could preserve the coronal fragment.     

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??Objective    To study the effect of different concentrations of ozone water on the expression of IL-6 in periodontal tissues of rat with periodontitis. Methods    A total of 70 male Wistar rats weighing??200 ± 20??g were chosen??randomly select five as normal control group??executed by cervical dislocation method????and the rest of the rats were made model of periodontitis. When the model was established??five periodontitis rats were randomly selected as no-treatment group??executed by cervical dislocation method??. The rest of periodontitis rats were randomly divided into ozone water treatment group and control treatment group for periodontal pocket rinsing. The general conditions and pathological changes of the periodontal tissues were observed. Immunohistochemical staining was conducted to determine the expression of IL-6 in the periodontal tissues. Results    The level of IL-6 in periodontal tissues of rats of no-treatment group was much higher than that in the normal control group??P < 0.05??. The level of IL-6 in the treatment groups was much lower than that in the no-treatment group??P < 0.05??. In each period of rinsing??at 15mg/L of ozone water treatment group??the expression of IL-6 in periodontal tissue was lower than that in other concentration groups ??5mg/L??10mg/L????P < 0.05????but there was no significant difference compared with the control treatment group. Conclusion    The ozone water can reduce the IL-6 level in periodontal tissues in rats and the effect is more obvious in concentration of 15mg/L??which has certain treatment effect on periodontitis.