血小板激活因子在心肌缺血再灌注损伤中的作用

用麻醉大鼠开胸冠状动脉结扎模型,研究血小板激活因子(PAF)在心肌缺血-再灌注损伤中的作用。观察指标及分组:(1)缺血及再灌注性心律失常:记录心电图室早个数对数值(1gPVC)、室速与室颤总时程对数值[1g(VT+VV)]及心律失常记分。分假结扎、缺血30min、缺血7min再灌注30man 3组,后二组各分为PAF拮抗剂BN50739(10mg/kg)预处理组、PAF(30ng·kg~(-1)·min~(-1))持续静滴及溶     

An experimental study of intravascular stent in abdominal aorta of atherosclerotic miniature pigs.

To study the effects of nitinol alloy stent in the treatment of atherosclerotic arterial stenosis, eight miniature pigs were subject to abdominal aortic balloon denudation and high-fatty food. Then 8 nitinol alloy stents were implanted into each abdominal aortas of pigs. The pigs were equally divided into two groups. One group was given captopril (3 mg / kg / d). All animals were sacrified) for pathological examination 6 to 10 months after stent implantation. The degree of arterial intima proliferation in the areas of stent implantation not significantly different from that of areas of balloon denudation alone; the atherosclerotic lesions were found at the arterial surface of stent implantation sites. The intima layer was rich in smooth muscle cells, with atherosclerotic plaque formed around the stent wire. On the other hand, significant decrease in arterial intima proliferation was found in group Ⅱ with no atherosclerotic plaque. The arterial stenosis resulting from atherosclerotic lesion could not be     

MA－4210型尿液分析仪潜血试验强阳性蛋白质试验阴性实验现象分析

实验发现血红蛋白尿浓度约为Ｈｂ＝１０－０．６ｍｇ／Ｌ时，使用尿液分析仪检测尿常规，可出现潜血试验（Ｂｌｄ）强阳性，但蛋白质半定量试验（Ｐｒｏ）阴性现象。分析此现象是因为Ｂｌｄ和Ｐｒｏ实验敏感性不同而产生的，与血红蛋白的珠蛋白结构无关。     

对分离性癔症心理治疗的忽视

心理治疗是治疗津症的主要而有效的方法，但在临床实践中，对分高性疲症治疗的主要方法则是药物治疗，对分离性疲症的心理治疗有所忽视。现将我院93例分离性疲症的治疗情况分析如下。1资料与方法76年以来收住院的93例最症均符合分离住遗症的疹断。其中男46例，女47例，平均年龄34．75士966岁（Z士SD）；已婚79例，未婚8例，离丧再婚6例；文盲15例，小学41例，初中30例，高中5例，中专2例；健康者76例，心身疾病史者6例，其他病史者11例；精神疾病家族史阳性25例，阴性68例。平均病程：41．0士6．58（x士SD）。内向性格者59例，外向性格者3…     

纹沼螺感染华支睾吸虫尾蚴的季节性动态观察

作者等于1978年以来在辽宁铁岭县对纹沼螺感染华支睾吸虫尾蚴的消长情况,作了季节性动态观察。结果表明:纹沼螺感染华支睾吸虫有明显的季节性变化,6月下旬和7月上旬感染率最高,分别为15.8%和19.2%;纹沼螺的感染率还和螺本身的生长、发育情况有密切关系,老螺的感染率远较当年生的成螺的感染率为高;雌螺的感染率明显高于雄螺的感染率。     

Eliminating Intensive Postoperative Care in Same-day Surgery Patients Using Short-acting Anesthetics

Background: A multidisciplinary effort was undertaken to determine whether patients could safely bypass the postanesthesia care unit (PACU) after same-day surgery by moving to an earlier time point evaluation of recovery criteria.

Methods: A prospective, outcomes research study with a baseline month, an intervention month, and a follow-up month was designed. Five surgical centers (three community-based hospitals and two freestanding ambulatory surgical centers) were utilized. Two thousand five hundred eight patients were involved in the baseline period, and 2,354 were involved in the follow-up period. Outcome measures included PACU bypass rates and adverse events. Intervention consisted of a multidisciplinary educational program and routine feedback reports.

Results: The overall PACU bypass rate (58%) was significantly different from baseline (15.9%, P < 0.001), for patients to whom a general anesthetic was administered (0.4-31.8%, P < 0.001), and for those given other anesthetic techniques (monitored anesthesia care, regional or local anesthetics; 29.1-84.2%, P < 0.001). During the follow-up period, the average (SD) recovery duration for patients who bypassed the PACU was significantly shorter compared to that for patients who did not bypass, 84.6 (61.5) versus 175.1 (98.8) min, P < 0.001, with no change in patient outcome. Patients receiving only short-acting anesthetics were 78% more likely (P < 0.002) to bypass the PACU after adjusting for various surgical procedures.     

肿瘤的血行转移与血粘状态的关系

肿瘤的转移是迄今尚未解决的医学难题之一。近年来,血行转移和高血粘状态的关系引起了人们广泛的兴趣。Dintenfass和Milton于1973年认为,肿瘤细胞能否成功的扩散和转移,血液的流体力学和流变学与其关系极大,即血粘度的升高和组织灌注效率的降低给肿瘤的转移提供了条件。避免血液瘀滞和涡流的出现,保证充足的血流,都可能有助于对抗肿瘤细胞的转移与留宿。