Effects of seawater immersion combined with open abdominal injury on the expression of NF-κB,and IκBαof small intestine in rats

Objective To observe effects of seawater immersion combined with open abdominal injury on the expression of NF-κB,and IκBαas well as the change pattern in rats. Methods Ninety-one Wistar rats were randomly divided into 3 groups: the control group (n =7), the open abdominal injury group(n =42) and open abdominal injury combined with 1-hour seawater immersion group ( n =42). The expression of NF-κB,andIκBαin small intestine tissues was measured by Western blot and statistical analyses were also made in the study. Results The expression of NF-κB,in the seawater immersion combined with open abdominal injury group increased significantly 3 hours after injury, when compared with that of the open abdominal injury group(P<0. 05), whereas the expression of NF-κB, of the pure injury group was slightly lower than that of the control group, but no statistical differences could be seen between them(P>0.05). The change pattern in the expression of IκBαwas quite the opposite to that of NF-κB. Conclusions NF-κB seemed to be rapidly and persistently involved in the whole inflammatory response to trauma induced by opened abdominal injury and seawater immersion, when a comparison was made with the pure open abdominal injury group. Injuries for the rats in the open abdominal injury combined with seawater immersion group were serious, and the feedback mechanism for NF-κB was not established for quite a long time.     

纤维支气管镜检查者心理疏导

加强接受纤维支气管镜(以下简称纤支镜)检查病人的心理疏导对提高疾病确诊率有重要意义。由于纤支镜检查病人多有紧张、恐惧心理影响正常操作，为此我们对50例接受纤支镜检查的病人进行心理疏导，与对照组50例相比。现报道如下。     

急性心肌梗死35例溶栓治疗的观察及护理

急性心肌梗死(AMI)早期溶栓治疗已成为选择性AMI患者最重要的紧急疗法.冠状动脉闭塞后溶栓效果与发生闭塞后开始治疗的时间呈明显正相关.     

改良11肋间切口在肾脏手术中的应用

我院2002—2004年采用改良第11肋间切口进行肾脏手术11例，疗效满意，报告如下。     

看过这部电影能救你的命——和洋快餐说再见

《给我最大号》在美国上演,这部纪录片长98分钟,记录了故事的主人公摩根·斯普尔洛克在30天里吃麦当劳的整个记录。在拍片之前,主人公身高1.9米,体重不足84公斤。为了证明绝非做假,斯普尔洛克特别请三位医生为整个实验过程做记录,定期追踪他的健康状况。然后,他出发上路,到美国20个城市拜访医生、健康顾问、厨师、小孩,探讨健康与快餐的关系。实验开始,他每日三餐,只吃麦当劳销售食品,包括饮料,并且不买大套餐。在试验的两星期后,医生警告他,他的肝脏受到严重损伤,应当停止试验,但他没有听医生劝告,继续实验,三周左右,他的心脏开始出现异常,…     

老年不稳定型转子间骨折的内固定选择及术后并发症原因分析

目的：探讨不稳定型老年转子间骨折的内固定方法选择及术后发生并发症的原因．方法：对手术治疗的65例不稳定型老年转子间骨折进行回顾分析．结果：65例随访12～82个月(平均36．2个月)，优良率81．5％．并发症主要为髋内翻畸形5例、内固定松动断裂3例和术后诱发原有合并症2例．结论：对老年不稳定转子间骨折的治疗，应针对不同的骨折类型，以及患的全身状况，选择最适合的内固定，主要选用股骨近端交锁髓内钉(PFN)和动力性髋部钉(DHS)，外固定架和多枚钉固定不宜采用．     

甘露消毒丹内服加中药外敷治疗带状疱疹33例

2000年3月—2005年10月,笔者采用甘露消毒丹内服,同时加用中药外敷治疗带状疱疹患者33例,取得显著疗效,现报道如下。1临床资料1·1一般资料本组男19例,女14例,年龄最大83岁,最小19岁;病程最长12 d,最短2 d;病变发生部位:头面部5例,颈背部4例,胸肋部12例,腰背部9例,臀部3例;临床     

统计推断中的检验效能分析

检验效能是假设检验中判断检验好坏的重要指标，但由于检验效能模型构造的复杂性和计算上的难度，使得检验效能的研究鲜有报道。简要的论述了检验效能在统计推断中的作用，并介绍了ＰＡＳＳ统计软件     

优降糖致低血糖与精神失常一例报告

病例:男,60岁。因高血压20年,头晕及胸闷加重3天入院。平素无多饮、多食和多尿史。家庭无精神失常史。体检:BP17.5/12kPa,营养一般,意识清楚。肺正常,心浊音界向左扩大,心率76次/分,A_2>P_2,无杂音。尿常规与肝功能正常。血肌酐137mmol/L,尿素氮5.5mmol/L。心电图示左室肥厚劳损。给极化液、复方