标本溶血对电化学发光免疫法结果的影响

目的探讨标本不同程度溶血对电化学发光免疫法(ECLIA)测定结果的影响。方法将血液标本人为干预成不同程度的溶血标本,使用ECLIA检测各组标本中的甲状腺功能、肿瘤标志物、内分泌激素等共28项指标的浓度并做分析。结果标本溶血可使胰岛素(INS)浓度降低,使叶酸(FA)、神经元特异性烯醇化酶(NSE)浓度升高,重度溶血有使铁蛋白测定结果偏高的趋势,但差异无统计学意义,其余指标测定结果不受溶血的影响。结论除某些项目外大部分溶血标本的ECLIA测定结果没有受到影响。测定INS、FA、NSE时应绝对避免使用溶血标本,以确保结果准确。     

乘用车致行人头部损伤程度调查及分析

目的 缺乏保护的行人在道路交通事故中易受到伤害,行人头部损伤是导致其残疾和死亡的首要原因.方法 设置调查条件,调查2006～2010年间重庆、北京和山西等地行人交通事故.行人按年龄分为儿童(<15岁),青壮年(≥15岁或﹤65岁)和老年行人组(≥65岁),行人损伤按人体损伤鉴定标准分为轻伤、重伤和死亡.用AIS2005...     

创伤性脑水肿的在体研究

目的 探讨在体研究创作性脑水肿的方法。方法 选择１５个频率点,测量大鼠中度颅脑的创伤后伤区组织的电阻抗,分析脑水肿的变化。结果 伤后早期细胞外液电阻（Ｒｅ）明显下降,细胞内液电阻（Ｒｉ）无明显变化,Ｒｅ／Ｒｉ也明显下降;６ｈ后Ｒｅ略有升高,Ｒｉ明显下降,Ｒｅ／Ｒｉ明显增加;伤后２４～７２ｈ脑水肿达高峰,伤后７基本恢复。结论 伤后早期电阻抗的变化提示发生了血管源性脑水肿,伤后６ｈ电阻抗变化表明细胞内     

松质骨的一维撞击动力响应

基于对松质骨结构特征的观察,引入了描述松质骨的两相多孔弹性模型,对松质骨在一维撞击载荷作用下的动力响应进行了深入的分析。研究表明：由于松质骨中流体组分的扩散和流动,松质骨呈现着一种强烈的表观粘弹性行为以及能量耗散性质。     

ECG-6951D型心电图机定标原理分析与故障解决方案

心电图机的定标在临床中主要用于测量心电信号幅度大小和校正机器灵敏度。通过对ECG-6951D型数字心电图机定标的原理、技术流程以及电路进行分析,归纳总结定标电路常见的3种故障现象和故障处理方法,为数字心电图机维修提出解决方案。     

阿德福韦酯合清肝解毒汤治疗慢性乙型肝炎疗效和HBV-YMDD变异的关系

目的:观察阿德福韦酯联合清肝解毒汤治疗慢性乙型肝炎疗效与HBV-YMDD变异的关系。方法:用随机抽样法选取我院门诊慢性乙型肝炎患者,经患者同意自愿选择治疗方法,分联合治疗组和对照组各60例,联合组用阿德福韦酯和清肝解毒汤治疗,对照组用阿德福韦酯治疗,两组治疗后又根据HBV-DNA的情况各分HBV-DNA(-)组、野生组、变异组。观察两组用药18个月(近期)和停药后6个月(远期)HBV-YMDD变异率、HBV-DNA转阴率、HbeAb(+)、ALT、TBIL的变化,并进行统计分析。结果:两野生组近期ALT、TBIL,远期HBV-DNA转阴率、ALT、TBIL均有显著性差异(P0.05);联合野生组近期与远期ALT、TBIL比较均有显著性差异(P0.05),对照组无显著性差异。两野生组近期、远期HBV-DNA转阴率、ALT、TBIL与变异组比较均有显著性差异(P0.05);两变异组近期、远期HBV-DNA转阴率、ALT、TBIL及两组各自近期与远期间比较均无显著性差异(P0.05)。联合组近期和远期变异率较对照组的同期低(P0.05);联合组的近期和远期变异率无显著性差异(P0.05),对照组远期变异率较近期高(P0.05)。结论:HBV-DNA变异是影响慢性肝炎疗效的主要原因;联合用药可促进肝功能的恢复,提高HBV-DNA的转阴率,降低HBV-YMDD的变异率。     

侧碰假人颈部标定系统的实验研究

目的研究"侧碰假人颈部标定系统"的设计方法和加工技术。方法采用"摆臂撞击原理",设计"ES-2型侧碰假人颈部标定系统";开发国产化的新技术、新方法,研制该标定系统中的两个关键设备,即"摆臂装置"和"头颈弯曲角测量装置";根据ECE R95标准的相关技术要求,对该标定系统进行6次验证实验。结果摆臂装置产生的摆臂初始速度3.36～3.48 m/s、摆臂对吸能块的碰撞速度-时间曲线均符合ECE R95标准要求;头颈弯曲角测量装置能较为准确地检测出ES-2型侧碰假人头颈部的"最大前摆基本角"、"最大后摆基本角"和"最大头颈弯曲角"。结论 "ES-2侧碰假人颈部标定系统"简便、实用,基本满足ECE R95标准要求;其设计方法和加工技术具有一定的应用价值。     

Establishment of the model of motorcyclist ejection injury

Objective： To establish the device and model of motorcyclist ejection injury. Methods： Based on our laboratory devices, a motorcyclist ejection injury simulation system was developed. A total of ! 8 pigs were approved by the local animal experi- mentation and ethics committee to serve as the motorcyclist substitutes. In this ejection motion, the animal rode freely at the motor driver seat and was straightly accelerated by means of our custom motorcyclist ejection injury simulation system. When it was speeded up to the preset velocity （v=30, 40 or 50 km/h） at the preset position, the animal was ejected forward. Pathological and dynamic analyses were conducted, accompanied with the high-speed photograph, acceleration/velocity signal test, gross observation and light microscope examination as well as the abbreviated injury score-injury severity score （AIS-ISS） scale. Results： The high-speed photograph indicated that during the ejection procedure the motorcycle was first arrested and decelerated suddenly, and then the motorcycle driver was ejected forward, accompanied with the rotation motion in the air. Finally, the head, shoulder and thorax of the ejected animal impacted directly on the hard ground. Varying degrees of injury focusing on the liver, heart, lung and spleen were found. There existed a significant positive correlation between ISS and the ejection velocity of the motorcycle drivers （ISS=16.7±2.9 for 30 km/h, 25.0±0.0 for 40 km/h and 37.3±1.0 for 50 km/h）. The detailed injury characteristics were as follows： for the mildly injured animals, there were interlobar gaps or leaf gaps and lobar surface blood coagulation blocks in the liver, and mild lung hemorrhage; for the severely injured animals, there were liver comminuted laceration, moderate lung hemorrhage and heart injury. Animals suffering from the most severe injuries died half an hour later. Conclusion： The new injury model stated in this paper has a high stability and good repeatability, and is likely to be helpful to deeply investigate the injury mechanisms and protection countermeasures of motorcyclist ejection injury.     

联合检测四项生化指标对鉴别诊断良恶性胸腔积液的意义

目的探讨C反应蛋白质(CRP)、乳酸脱氢酶(LDH)、癌胚抗原(CEA)、腺苷脱氨酶(ADA)联合检测在鉴别胸腔积液性质中的应用价值。方法检测83例胸腔积液中的CRP、LDH、ADA、CEA。然后进行结果比较。结果良性组胸腔积液中的CRP、ADA水平明显高于恶性组(P<0.05),恶性组胸腔积液中的CEA、LDH明显高于良性组(P<0.05)。CRP+ADA+LDH+CEA联合检测鉴别诊断良恶性胸腔积液的敏感度、特异度和准确度要大大高于各单项指标检测。结论联合检测CRP、ADA、LDH、CEA在鉴别胸腔积液性质中有一定的临床意义。     

Animal study on lung injury caused by simulant segmented shock waves

ｓｕｇｇｅｓｔｓｔｈａｔｔｈｅｏｒｇａｎｓｗｉｔｈａｉｒｃａｖｉｔｙ,ｓｕｃｈａｓｔｈｅｌｕｎｇｓ,ｍａｙｐｒｏｂａｂｌｙｂｅｄａｍａｇｅｄｉｎｔｈｅｅｘｐａｎｓｉｎｇｄｕｒａｔｉｏｎｏｆｓｈｏｃｋｗａｖｅｓ,ｔｈｅｒｅｉｓｌｉｔｔｌｅｉｎｆｏｒｍａｔｉｏｎａｂｏｕｔｉｔ.13Ｔｈｅｐｕｒｐｏｓｅｏｆｔｈｉｓｓｔｕｄｙｉｓｔｏｉｎｖｅｓｔｉｇａｔｅｔｈｅｅｆｆｅｃｔｓｏｆｔｈｅｓｉｍｕｌａｎｔｐｒｅｓｓｕｒｅｗａｖｅｓｄｕｒｉｎｇｔｈｅｐｒｏｃｅｓｓｏｆｔｒａｎｓｍｉｓｓｉｏｎｏｆｓｈｏｃｋｗａｖｅｓ…