地尔硫静脉注射对偏头痛急性发作的疗效

目的：观察地尔硫静脉注射对偏头痛的疗效。方法：偏头痛急性发作病人３４例（男性６例，女性２８例；年龄３１±ｓ５ａ），采用地尔硫注射液１０ｍｇ加入２５％葡萄糖液２０ｍＬ中静脉注射，所有病人均仅注射１次。结果：头痛消失或缓解者２９例，有效率为８５％，无１例出现不良反应。结论：地尔硫对偏头痛急性发作疗效满意，值得进一步验证应用。     

血管紧张素转换酶抑制剂——甲巯丙脯酸

甲巯丙脯酸(Captopril,CPT)是新近发现的新型抗高血压药物。它作用于肾素-血管紧张素-醛固酮(R-A-A)系统,不仅对原发性高血压病,而且对除原发性醛固酮增多症以外的继发性高血压均有降压作用。此外,本药还用于治疗难治性充血性心力衰竭和肾血管性高血压的诊断等方面。现就其作用机理、临床应用和不良反应等温习如下:作用机理 R-A-A系统在调整血循环中的作用已获公认,其对高血压的产生可归纳见图1: 肾素系由肾球旁装置分泌的蛋白水解     

血清心肌肌钙蛋白T检测对非典型心肌梗塞的诊断价值

目的:着重探讨心肌肌钙蛋白T(cTnT)测定在非典型心肌梗塞诊断价值。方法:应用半定量方法对43例非典型心肌梗塞患者cTNT、CK、LDH进行检测。结果:心肌梗塞后cTNT升高持续时间长于CK、LDH,在非典型心肌梗塞后第七天CK无一例阳性,LDH阳性23%,而cTNT阳性47%。cTNT与CK,cTNT与LDH之间有非常显著性差异(P<0.01)。结论:心肌梗塞中cTNT持续时间特别长,且特异性高,所以cTNT对非典型心肌梗塞有独特的诊断价值。     

生脉注射液对损伤心肌细胞乳酸脱氢酶及心肌细胞超微结构的影响

本实验运用体外培养心肌细胞,观察了中药生脉注射液对阿霉素引起心肌细胞损伤时,心肌细胞内乳酸脱氢酶释放及超微结构的影响。结果表明,生脉注射液30、100、300mg/L 对阿霉素1 mg/L 作用4 h 引起的培养心肌细胞乳酸脱氢酶释放没有影响;对其引起的心肌细胞超微结构损伤也无改善作用。结果提示:生脉注射液对阿霉素引起的心肌损害的保护作用,可能是在整体情况下产生的。     

MYOCARDIAL ENZYME LEAKAGE AND SUCCINIC DEHYDROGENASE ACTIVITY OF MITOCHONDRIA CORRELATED WITH MORPHOLOGICAL CHANGES IN THE ANOXIC ISOLATED PERFUSED RAT HEART

Langendorff isolated perfused rat heart system was used to study the myocardial enzyme leakage and succinic dehydrogenase activity of mitochondria, and to investigate their correlation with the morphological changes due to anoxia-induced injury. 84 male Wistar rats were used and divided into the aerobic control group and the anoxic group. Besides the mitochondrial structural changes and the myccardial cell menbrane permeabilily defects observed, the SDH activity of mitcchondria was reduced and the CPK release increased. The morphological, functional and biochemical changes in anoxic rat heart correlated with each other very well.     

Influence of Shengmai Capsule (生脉胶囊) on recovery of living capacity in patients after myocardial infarction

ABSTRACT Objective： To observe the effect of long-term application of Shengmai Capsule （生脉胶囊, SMC） on recovery of patients after myocardial infarction. Methods： A total of 120 myocardial infarction patients were assigned into two groups. Changes of angina pectoris, electrocardiogram （ECG）, living capacity and heart function in patients were observed after 6-month treatment. Results： The total effective rate in alleviating angina pectods was 90.0% and that in improving ECG figure was 93.3% in the treatment group, both were significantly higher than those in the control group, 73.4% and 70.0% respectively （P〈0.05）. The Karnofsky Performance Status scores of heart function were increased and the Activity of Daily Living scores in living capacity decreased in both groups, but the improvements were better in the treatment group （P〈0.01 and P〈0.05）. The parameters of cardiac function, including cardiac output, stroke volume, cardiac index and ejection fraction, were increased in both groups, but the increments in the treatment group were more significant （P〈0.01 or P〈0.05）. Conclusion： Long-term application of SMC could effectively prevent and treat angina pectoris, improve the living capacity and accelerate the recovery of heart function in patients after myocardial infarction.     

Observation on Therapeutic Effects of Shengmai Powder (生脉散)in Treating Acute Viral Myocarditis

Objective: To evaluate the clinical efficacy of Shengmai Powder (SMP, 生脉散) in treating a-cute viral myocarditis objectively. Methods: One hundred and twenty-four patients with acute viral myocarditis were randomized into the treated group (SMG, n = 64) and the control group(CG, n = 60 ). Such myo-cardial nutrient medicine as ATP, CoA , Vit-C, were given to both groups. And to the treated group, 40 ml of Shengmai Injection per day was given intravenously for 2 weeks, which was followed by oral intake of Shengmai granule, one package three times daily for another 2 weeks in total. The same anti-arrhythmia agents were applied to both groups, and no fructose-1, 6-diphosphate (FDP) for either. Semi-quantitative scoring method was adopted to observe such symptoms as chest stuffiness, palpitation and chest pain before treatment and four weeks after treatment. Meanwhile, EGG, dynamic ECG by Holter monitor, left ventricular end-diastolic dimension (LVEDD), left ventricular ejection fraction (LVEF), serum neut     

1,6-二磷酸果糖治疗冠心病97例

目的：比较国产与进口１，６－二磷酸果糖（ＦＤＰ）对冠心病心绞痛的作用。方法：冠心病心绞痛病人１０７例，以单盲、对比法分为国产ＦＤＰ组（６６例，年龄６１±ｓ７ａ）；进口ＦＤＰ组（３１例，年龄６２±１０ａ）；对照组（２０例，年龄５９±８ａ）。国产或进口ＦＤＰ组均以１０ｇ溶于注射用水１００ｍＬ中，对照组用５％葡萄糖１００ｍＬ，３组均作静脉滴注，１０～１４ｍｉｎ内滴完，ｂｉｄ，共７ｄ。结果：国产与进口ＦＤＰ及对照组抗心绞痛症状疗效依次为８３％，８１％及２５％；心电图改善率依次为６７％，６２％及１２％；国产与进口ＦＤＰ组组间比较均Ｐ＞０．０５，２组均优于对照组（Ｐ＜０．０１）。且２组不良反应相似，均较轻微。结论：国产与进口ＦＤＰ治疗冠心病心绞痛疗效均有效。     

多烯康胶丸对老年急性心梗病人通便作用的临床观察

<正> 保持大便通畅是医护急性心梗(AMI)的重点措施之一。本文报告浙江普陀山制药厂生产的鱼油制剂——多烯康胶丸对老年AMI病人大便情况的影响。     

宗教信仰与大学生心理健康的相关性

目的 探讨大学生人群宗教信仰与心理健康的相关性,为大学生心理健康干预提供参考.方法 使用DUREL量表及K10量表对宁夏2所高校1410名大学生进行调查,并对调查结果进行统计分析.结果 1278名学生完成调查,其中信仰佛教229名(17.9％),伊斯兰教381名(29.8％),其它教79名(6.2％),无信仰589名(46.1％);K10量表评分正常范围的643名(50.3％),2级393名(30.8％),3级172名(13.4％),4级70名(5.5％).IR维度与K10总分显著相关(r=0.111,P=0.000),控制性别、民族后IR维度与心理健康水平的相关性仍有统计学意义(OR=l.05,95％ CI:1.01 ～ 1.10).结论 宗教信仰与大学生心理健康评分显著相关,需要前瞻性研究进一步验证因果关系.