透出液蛋白丢失与连续性非卧床腹膜透析患者营养不良-炎性反应-动脉硬化综合征的相关性

Objective To investigate the impact of peritoneal albumin leakage on malnutrition-inflammation-atherosclerosis (MIA) syndrome in continuous ambulatory peritoneal dialysis (CAPD) patients. Methods A cross-sectional study of a cohort of 130 CAPD patients without edema or active infection was performed. In order to identify peritoneal transport characteristics in CAPD patients, a standard peritoneal equilibration test (PET) was carried out. For malnutrition and inflammation, serum albumin and high-sensitivity C-reactive protein (hs-CRP) levels were measured. Mean-carotid artery intima media thickness (IMT) was used to determine atherosclerosis. Residual glomerular filtration rate (rGFR) was defined as the average of 24-hour urinary urea and creatinine clearances. Results Pearson and Spearman correlation analysis showed that peritoneal albumin leakage amount was positively correlated with age, body mass index, night dwell time, blood glucose, 4 h D/P creatinine levels and hs-CRP levels (r=0.204, P<0.05 ;r=0.314, P<0.01; r=0.265, P<0.01; r=0.212, P<0.05; r=0.401, P<0.01; r=0.216, P<0.05); whereas it was negatively correlated with diastolic perssure, serum albumin levels, glucose level of dialyzate and peritoneal Kt/V (r=-0.209, P<0.05; r=-0.123, P<0.05; r=-0.271, P<0.01; r=-0.212, P<0.01). Overall, there was no correlation between peritoneal albumin leakage and IMT. Patients was significantly greater (P<0.01), and there was a positive correlation between peritoneal albumin leakage amount and IMT (r=0.650, P<0.01). Conclusions Peritoneal albumin leakage is significantly associated with peritoneal transport characteristics, malnutrition and inflammatory state in CAPD patients. High peritoneal albumin leakage amount is a risk factor for atherosclerosis in patients with rGFR less than 1 ml·min-1(1.73 m2)-1.     

用国产碘伏液作腹透消毒液的研究

为了减轻持续性不卧床腹膜透析(CAPD)的经济负担,特别是使用O型管组患者,我们试用价廉的国产碘伏液作O型管组消毒液,代替现时用的昂贵的进口的amukin消毒液。 方法 54名我院用O型管组作CAPD患者,随机分为二组,28例用amukin消毒液(0.5％次氯酸钠),26例用国产的0.5％碘伏(聚维酮碘,povidon iodine),观察其使用后的腹膜炎发生率,并将O型管分别浸干两     

腹膜透析全天护理热线咨询电话的内涵与实践

科学的发展需要概念的改变。在护理学的发展中 ,正是由于创立 ,发展和应用了一些新概念 ,而使得这门学科面目一新。作者在护理工作中很受下面两个概念的启发 ,特先简单介绍如下。1　新概念的启迪1.1　绿色化学的概念　近十多年来 ,绿色化学的浪潮正越来越重要地影响着人类的未来。绿色是生命的颜色 ,热爱绿色 ,也就是热爱生命。绿色化学认为依靠传统的控制技术对环境的保护和改善是有限的 ,实现环境保护的新水平 ,必须寻找新的途径。绿色化学早已渗透到护理科学中 ,护理科学正在开发和不断寻找新的途径。社区护理和整体护理模式 ,以及Ｏｒｅ…