抵抗素样分子β在肠上皮化生型Barrett食管中的诊断价值

Barrett食管(Barrett's esophagus,BE)是一种镜下活检可见的食管黏膜肠上皮化生病变.抵抗素样分子β(resistin-like molecule beta.RELMβ)是一种新近发现的杯状细胞特异性蛋白[1].     

Expression of PirB in normal and injured spinal cord of rats

The expression of paired immunoglobulin-like receptor B (PirB) in normal and injured spinal cord of rats was investigated. The SD rat hemi-sectioned spinal cord injury (SCI) model was established. Before and 1, 3, 7, 10 days after SCI, the spinal cord tissues were harvested, and Western blot and immunohistochemistry were used to examine the expression and location of PirB. The results showed that the expression level of PirB in the normal spinal cord of SD rats was low. At the first day after SCI, the expre...     

HE染色质控组织的选取及优化

<正>良好的HE切片对病理诊断至关重要，高质量的HE染色红蓝对比鲜明；可见3种红色(大红、粉红和紫红),显示色彩亮丽、对比鲜明及细腻的细节；核染色质清晰^[1]。使用质控组织评估染色效果是HE染色质量控制的重要手段，以往质控组织多选用单一类型组织，存在较大的局限性，无法全面地反映不同类型标本的染色效果。本科室运用组织芯片进行HE染色质控，取得了良好的效果，同时也遇到了组织收集和芯片蜡块制备难度大、对质控人员能力要求高、质控时间偏长等问题，     

TFEB基因扩增性肾细胞癌1例

本文报道1例发生于64岁男性的TFEB基因扩增性肾细胞癌的病例。TFEB基因扩增性肾细胞癌是一种极为罕见的高级别侵袭性肾细胞癌, 其临床特征、生物学行为、形态学、免疫表型及分子病理学特征均不同于TFEB基因重排性肾细胞癌, 诊断时需要注意准确区分两者, 避免误诊。