非匹配负波对遗忘型轻度认知障碍诊断和预后的价值

Objective To evaluate the value of event-related potential mismatch negativity(ERP-MMN)for diagnosis and prognosis of amnestic mild cognitive impairment(aMCI).Methods 181 people were enrolled in this study,including 102 aMCI patients and 79 normal people and all of them underwent the clinical symptom and performance of neuropsychologieal measures and cranium imaging and examination of MMN.aMCI patients were judged to progress to Alzheimer's disease(AD)or not by clinical symptom and performance of neuropsychological measures during 1 year follow-up period.Through analysis of peak latency (PL)and amplitude(Amp),the value of MMN in diagnosis of aMCI and normal subjects was assessed,judging aMCI progress to AD or not.Results In contrast to normal control subjects(NC),PL of MMN in subjects of aMCl was significantly longer and Amp was significantly shorter,PL of MMN(312.7±25.7)ms vs(285.1±28.8)ms(t=6.81,P<0.01),Amp(3.5 ±1.3)μV vs(4.7±1.1)μV(t=-6.37,P<0.01).Moreover,PL of MMN in subjects of aMCl which would progress to AD was significantly longer than of subjects of aMCI which would not progress,(332.2±24.1)ms vs(307.5 ±24.0)ms(t=2.75,P=0.007).However.significantly difference was not observed in Amp of MMN and neuropsychological measures between subjects of aMCI would progress and not.Conclusions MMN can be used in auxiliary diagnosis and judging prognosis of aMCI.It is appropriate when is required to reflect and monitor periodic cognitive state of subjects of aMCI.     

继承与发展传统骨科 打造特色品牌专科--与时俱进的广州市正骨医院

广州市正骨医院（原名广州市越秀区正骨医院）是一家有51年历史,以中医骨伤为主的专科医院。几代正骨人以坚持不懈的求索奋斗打造了“正骨”金色品牌。     

铜仁地区1452例阴道分泌物检测结果分析

目的:了解妇科阴道疾病的病原体检出率,为临床预防和治疗提供参考。方法:对1452例门诊妇科患者阴道分泌物进行白带常规检查和细菌性阴道病的检测。结果:BV检出率为32.4%,假丝酵母菌检出率为23.7%,假丝酵母菌+BV检出率为12.9%滴虫+BV检出率为5.1%,滴虫检出率为3.45%。结论:BV的检出率高,在阴道分泌物检查时即使清洁度正常也要注意查找病原菌,并应注意混合感染。     

思密达保留灌肠联合口服锌制剂治疗小儿腹泻56例临床分析

目的探讨思密达保留灌肠联合口服锌制剂治疗小儿腹泻的临床应用价值。方法将112例小儿腹泻患儿随机分为观察组和对照组各56例,对照组给予常规治疗方法,观察组在对照组的基础上给予思密达保留灌肠联合口服锌制剂,比较两组疗效。结果观察组总有效率94.64%,对照组总有效率74.98%,两组比较有显著性差异(χ2=8.3913,P<0.01)。结论采用思密达保留灌肠联合口服锌制剂治疗小儿腹泻具有良好的临床疗效,值得临床推广。     

健康体检满意度问卷调查结果分析与质量控制

体检客户满意度是指体检者在医院接受体检服务过程中的满意程度,是体检者对其体检过程的直接体验和亲身体会,是了解体检医疗服务质量的重要信息来源。体检中心是21世纪的朝阳产业,健康体检作为一种新型健康消费方式,成为人们了解自身健康状况、早期发现疾病、早期治疗疾病及规范健     

依达拉奉治疗进展性脑梗死的疗效观察

目的 观察依达拉奉治疗进展性脑梗死的临床疗效.方法 80例进展性脑梗死患者分为治疗组和对照组,对照组静脉滴注丹红,口服阿司匹林、普伐他汀等药,治疗组加用依达拉奉.结果 依达拉奉治疗组治疗14 d后神经功能缺损评分及有效率显著优于对照组(P＜0.05).结论 依达拉奉治疗进展性脑梗死疗效确切.     

非匹配负波对遗忘型轻度认知障碍诊断和预后的价值

Objective To evaluate the value of event-related potential mismatch negativity(ERP-MMN)for diagnosis and prognosis of amnestic mild cognitive impairment(aMCI).Methods 181 people were enrolled in this study,including 102 aMCI patients and 79 normal people and all of them underwent the clinical symptom and performance of neuropsychologieal measures and cranium imaging and examination of MMN.aMCI patients were judged to progress to Alzheimer's disease(AD)or not by clinical symptom and performance of neuropsychological measures during 1 year follow-up period.Through analysis of peak latency (PL)and amplitude(Amp),the value of MMN in diagnosis of aMCI and normal subjects was assessed,judging aMCI progress to AD or not.Results In contrast to normal control subjects(NC),PL of MMN in subjects of aMCl was significantly longer and Amp was significantly shorter,PL of MMN(312.7±25.7)ms vs(285.1±28.8)ms(t=6.81,P<0.01),Amp(3.5 ±1.3)μV vs(4.7±1.1)μV(t=-6.37,P<0.01).Moreover,PL of MMN in subjects of aMCl which would progress to AD was significantly longer than of subjects of aMCI which would not progress,(332.2±24.1)ms vs(307.5 ±24.0)ms(t=2.75,P=0.007).However.significantly difference was not observed in Amp of MMN and neuropsychological measures between subjects of aMCI would progress and not.Conclusions MMN can be used in auxiliary diagnosis and judging prognosis of aMCI.It is appropriate when is required to reflect and monitor periodic cognitive state of subjects of aMCI.     

联合检测孕妇血清雌三醇和胎盘泌乳素监测胎盘功能

目的:探讨血清雌三醇(E3)和胎盘泌乳素(HPL)联合测定监测胎儿-胎盘功能的应用价值。方法:对237例28孕周以上正常孕妇及63例疾病组孕妇E3和HPL水平进行放射免疫分析(R IA)测定。结果:妊娠合并高血压、胎儿宫内发育迟缓、妊娠合并糖尿病孕妇E3与HPL水平明显低于相同孕周的正常对照组;E3与HPL之间两者呈正相关;疾病组E3与HPL测定阳性率低于联合测定。结论:联合测定能大幅提高胎儿-胎盘功能低下的诊断率。     

高龄人工髋关节置换术患者的体位观察与护理

人工髋关节置换是指用生物相溶性和机械性能良好的材料制成的一种类似人体骨关节的假体,利用手术方法用人工髋关节假体来替换有病变的髋关节,其目的是解除疼痛,     

抗生素化学效价的快速高通量分析方法

为适应菌种的大规模筛选,以红霉素发酵为研究对象建立一套抗生素化学效价的高通量分析方法.该方法以硫酸显色法测定红霉素化学效价原理为基础,分析了检测器、微孔板介质、样品前处理操作条件等对检测的影响,结果表明该方法分析快速,结果稳定,且操作简单,试剂和样品用量少,适合高通量平行分析大批量样品.