久坐族谨防“经济舱综合征”

如果你需要成天久坐在办公室面对电脑、或者痴迷游戏玩起来就忘记时间，再或者是风雨无阻的出租车司机、经常伏案工作到深夜的学者、下肢手术后活动困难的患者、通宵打麻将的人士……只要长期久坐不动是你的生活常态，你就需要了解一种叫深静脉血栓的疾病，因为它与另一种非常危险的急症——肺栓塞紧密关联。     

浅析针灸急救

针灸学从古至今一直运用于临床急救中.它因其方便、迅速、灵验,被历代医家所重视.现综合古今文献,总结出一些针灸治疗急性病的经验.     

With autosomal dominant polycystic kidney disease,aortic dissection follows an abdominal aneurysm ten years later:a case report

A case of aortic dissection with a repaired abdominal aneurysm with prosthetic graft ten years ago in a 45-year-old woman is presented.Stanford type B dissection and multiple renal cysts diagnosed by contrast enhanced CT and an iliac false aneurysm by intraoperational angiography.Four stents were deployed to repair these arterial lesions with one fenestrated.With her only son revealed also with renal cysts by ultrasonogram,the diagnosis of autosomal dominant polycystic kidney disease (ADPKD) was confirmed.     

术后早期炎性肠梗阻64例临床分析

术后早期肠梗阻约90％为术后早期炎性肠梗阻，今报告64例。     

Stanford B型夹层动脉瘤模型的建立

随着高血压及其他相关因素的增加，胸主动脉夹层动脉瘤(thoracic aortic dissection，TAD)的发生率逐年上升，但其发病机制一直不清。我们在平时临床工作中观察到TAD的发生与中膜结构的异常关系密切。根据这一发现和在前人研究工作的基础。我们设计了一种新的方法来建立符合病理生理的Standford B型夹层动脉瘤模型。     

外伤性脾破裂非手术治疗46例临床分析

目的探讨外伤性脾破裂非手术治疗的可行性、适应证及其治疗效果。方法回顾性分析我院1990年1月至2005年1月收治的外伤性脾破裂非手术治疗46例临床资料。结果非手术治愈43例,3例因提前下床活动致大出血而中转手术,其中1例并发膈下脓肿,仍经保守治疗痊愈。无死亡病例。结论在严格掌握适应证前提下非手术治疗外伤性脾破裂安全可行,年龄及腹腔外合并伤不是影响非手术治疗的主要因素。     

股骨颈应力性骨折1例

1　病案摘要患者男 ,18岁 ,某部新战士。右髋部疼痛半个月 ,于 2 0 0 3年5月 2 8日入院。患者于发病前 1周因反复进行障碍训练 ,始有右髋部疼痛 ,徒步行走时加重 ,休息后减轻 ,疼痛与气候变化无关 ,无外伤史及午后潮热、盗汗史。体格检查 :患肢无短缩、屈曲、外旋等畸形 ,髋关节活动度 :屈曲 6 0°,外展 30°,后伸 10°,髋部局部无肿胀 ,纵轴叩痛 (- ) ,右腹股沟中点偏下压痛 (+) ,大粗隆未见升高或降低 ,与 Nolanlon线关系正常 ,托马斯征(- ) ,屈氏试验 (- ) ,辅助检查 :类风湿因子、抗“O”及血沉均正常 ,骨盆 X线示 :右股骨颈外下 1/3…     

血栓闭塞性脉管炎患者血浆源性外泌体miR-223-5p对人血管平滑肌细胞的影响

目的 探究血栓闭塞性脉管炎（thromboangiitis obliterans,TAO）患者血浆源性外泌体中miRNAs对人血管平滑肌细胞（human vascular smooth muscle cell,HVSMC）的影响。方法 从TAO患者和健康对照的血浆中提纯外泌体,进行miRNA测序。通过生物信息学分析鉴定差异表达的miRNA(differentially expressed miRNA,DEmiRNA),用RT-qPCR进一步验证。将PKH67荧光标记的外泌体与HVSMC共培养,采用CCK-8法和流式细胞术分别检测HVSMC的细胞活力和凋亡。使用双荧光素酶报告分析并确认miR-223-5p的下游靶点。结果 在TAO患者和健康对照之间共发现39个DE-miRNA,其中miR-223-5p是显著上调的miRNA。TAO患者血浆外泌体或miR-223-5p模拟物能降低HVSMC的细胞活力并促进细胞凋亡,miR-223-5p抑制剂可削弱TAO患者血浆源性外泌体的抑制和促凋亡作用。血管内皮细胞黏附分子1(vascular endothelial cell adhesion mole...     

获得性血友病A并下肢筋膜间隔综合征误诊病例报告

1病例资料女,32岁。因双小腿肿胀3天急诊以“双下肢深静脉血栓(DVT)”收入院。患者3天前无明显诱因出现双小腿肿胀伴酸痛、行走乏力。查体:双小腿肿胀,皮色深,皮温凉,皮肤张力高,右侧近足靴处皮肤有明显淤血斑,Homan征及腓肠肌压痛阳性。左侧髌骨下10 cm处小腿周径为50 cm,右侧     

Depressant effect and mechanism of atorvastatin on the chronic rejection of aortic allograft in rats

Objective To investigate the depressant effect and mechanism of atorvastatin on the chronic rejection of aortic allograft in rats. Methods： The models of abdominal aorta transplantation were made with micro-surgery in rats. The recipients were divided into three groups： allograft control group, atorvastatin-treated group and isograft control group. Vascular intimal thickness in all of the groups were observed by histological examination. The expression of PCNA and α-SMA were determined by immunohistochemistry. The content of nitric oxide was determined by nitrate reductase chromatometry. Results： The vascular intimal thickness in rats of atorvastatin-treated group （11.60% ± 2.40% ） were lower than those in allograft control group （34.60 % ± 6.40 % ; P 〈 0.05） and higher than those in isograft control group （1.15 % ± 0.65 %; P〈 0.05 ）. The expression level of PCNA was decreased in atorvastatin-treated group （4.80% ± 0.80% ） than allograft control group （18.40% ± 1.80% ; P〈0.05） and higher than isograft group （1.20% ± 0.40% ; P〈0.05）. Conclusion： The expression of PCNA in the transplant aorta could be suppressed by atorvastatin, which resalted in relief of chronic rejection of aortic allograft.