练习太极拳时心血管呼吸和代谢功能的改变

太极拳是中国传统的武术健身运动。近二、三十年来,北美和西方其他国家许多医学界和武术界人士对太极拳的健身作用越来越感兴趣。太极拳被认为是一种柔和的、放松的运动,可作为对慢性病者的一种放松性的康复性体操,同时,也是一种对一般中老年和青年人的健身运动。     

椎体强化的生物力学回顾(上)

介绍：骨质疏松的椎体其强度和刚度都会降低，这就意味着椎体的破坏负荷与抵抗压缩变形的能力均降低。强度和刚度的降低量与骨质疏松的严重程度呈正比。因为这些特性与骨小梁的密度有很大的相关性。椎体压缩性骨折后强度和刚度值与骨折前相比进一步降低。其临床结果是：（1）骨质疏松导致椎体强度降低，继而导致最初的骨质疏松性骨折，骨折后的椎体有进一步压缩性骨折的倾向。[第一段]     

七氟醚预处理对体外循环冠状动脉旁路移植术病人围术期心肌的保护作用

目的探讨七氟醚预处理对体外循环(CPB)下冠状动脉旁路移植术(CABG)病人心肌的保护作用。方法择期CPB下CABG病人40例,ASAⅡ级或Ⅲ级,随机分为2组(n=20):七氟醚组(S组)或异丙酚组(P组)。麻醉维持:P组靶控输注异丙酚,血浆靶浓度2～3μg/L,静脉输注芬太尼2～3μg·kg~(-1)·h~(-1);S组夹闭主动脉前,吸入0.5%～2%七氟醚,静脉输注芬太尼2～3μg·kg~(-1)·h~(-1),夹闭主动脉后靶控输注异丙酚,血浆靶浓度2～3μg/L,静脉输注芬太尼2～3μg·kg~(-1)·h~(-1)。于切皮前即刻、CPB前即刻、CPB后即刻、回ICU后即刻、6、12h记录心率(HR)、平均动脉压(MAP)、肺动脉楔压(PCWP)、中心静脉压(CVP)、心脏指数(CI)、体循环血管阻力指数(SVRI)。于麻醉诱导前、回ICU后即刻、6、12、24h采集静脉血,测定血清心肌肌钙蛋白I(cTnI)浓度。记录术后不良事件的发生情况。结果2组各时点MAP、PCWP、CVP、HR和SVRI比较差异无统计学意义(P>0.05);与切皮前即刻和P组比较,S组回ICU后各时点CI升高(P<0.05)。与P组比较,S组回ICU后各时点cTnI浓度降低(P<0.05)。2组病人术后均无死亡;2组心肌梗塞、房颤和心肌缺血的发生率差异无统计学意义(P>0.05);S组cTnI浓度>2ng/ml的发生率低于P组(P<0.05)。结论七氟醚预处理对体外循环下冠状动脉旁路移植术病人围术期心肌具有一定的保护作用。     

维吾尔族和汉族弱精子症病人精子mtDNA4977bp缺失相关性研究

目的探讨维吾尔族和汉族弱精子症病人精子mtDNA~(4977bp)缺失的相关性。方法本文采用聚合酶链反应(PCR)技术对60例标本分两组,维、汉各30例,其中精子活力正常标本(对照组)和弱精子症患者(观察组)各15例进行了精子线粒体DNA(mtDNA)缺失的研究。结果发现15例做内对照的维族精子活力正常人中仅有3例(20%)有mtDNA~(4977bp)缺失；而15例维吾尔族弱精子症患者中有10例(67%) mtDNA~(4977bp)缺失；两组4977bp缺失频率比较有显著性差异(P＜0．05)。15例做内对照的汉族精子活力正常标本中无mtDNA~(4977bp)缺失；15例汉族弱精子症患者中有12例(80%)mtDNA~(4977bp)缺失。两组4977bp缺失频率比较差异有显著性(P＜0．05)。同时发现维吾尔族男性不育症与汉族男性不育症mtDNA~(4977bp)缺失频率无显著性差异。结论维吾尔族和汉族mtDNA~(4977bp)缺失在弱精子症的发病中可能起重要作用。     

全科医生札记——布朗医生日记

伊萨贝尔和办公室以前的管理人员好像有点不同，就像马克．吐温提到的闪电与萤火虫的不同似的。她是个很实在的人，我的病人都很喜欢她。几个月前，她参与并完成了我们的总结报告，报告很有创意。于是我在便条上写道，“依莎贝尔，你做得非常出色”，并将它放在了她的办公桌上。今天我发现．那张便条仍放在桌子上，并且放在她收集的光盘上面。我想：赞美即使以便条的形式出现，也难以将它丢掉。[第一段]     

农药杀虫脒基对大鼠前脑细胞_(α2)—肾上腺受体与~3H-clonidine结合抑制效应研究

杀虫脒基(Chlordimeform,简称CDM)系甲脒类农药。结构式为在美已广泛地用于果树防病中,是有效的杀螨剂和杀虫剂。现我国也已生产和应用。CDM经口急性毒实验和经     

LIAN Fang (连 方)—An outstanding gynecologist

LIAN Fang,was born in Rongcheng City,Shandong Province in September 1957. In December 1982,she received her bachelor's degree. She has been engaged in clinical practice,scientific research and teaching at the Department of Gynecology,the Affiliated Hospital of Shandong University of Traditional Chinese Medicine.During this period,she received her master's degree from the Department of Gynecology of Integrated Chinese and Western Medicine in Nanjing     

Sinoatrial Node Electrogram Studies in Patients with Sick Sinus Syndrome

Sinoatrial node electrogram (SNE) was recorded successfully in recent years, using transvenous electrode catheter. Via SNE and intratrialelectrogram (IEG), one could measure sinoatrial conduction time(SACT) directly, observe sinoatrial node (SN) potential changes in cadiac cycles, diagnose some sinus arrhythmias which couldn't be confirmed by surface ECG. All these could offer accurate evidence for differential diagnosis of sick sinus syndrome (SSS). The authors recommend a modified method for the location of the electrode catheter, by which one can increase success rate of obtaining stable SNE. Using this method, the authors recorded SNE in 10 cases with SSS successfully.     

Effect of Some Thiol Chelators on Enzymatic Activities in Blood,Liver and Kidneys of Acute Arsenic（Ⅲ）Exposed Mice

The effects of meso 2,3-dimercaptosuccinic acid(DMSA),sodium 2,3-dimercaptopropane 1-sulfonate(DMPS)and S-adenosyl L-methionine(SAM)on the enzymatic acivities of mice were studied.The mice were given intraperitoneal(i.p.)injections of these chelating agents(1 mmol/kg) and 3 h later the activity of δ-aminolevulinic acid dehydratase(ALAD) in the blld,and aspartate aminotransferase(AST),alanine aminotransferase(ALT),γ-glutamyltranspeptidase(γ-GT）,alkaline phosphatase(ALP)in the liver and kidney were determined.The activity of blood ALAD was significantly increased by the administration of DMSA and SAM while DMPS had only a moderate effect.The activities of other hepatic enzymes changed little the mice were treated with these chelating agents,except for a significant reduction in hepatic ALP activity following DMPS administration.Arsenic(Ⅲ） administration markedly increased the activities of ALT and ALP in the liver and kidneys.The changes in the enzymatic activities by treatment with arsenic were prevented by injection of DMSA,DMPS and SAM,DMSA being the most effective.These results indicate that DMSA,DMPS and SAM wer not toxic to the liver or kidnys of mice and that treatment with DMSA is more effective than DMPS or SAM in protecting mice from acute hepatic or renal toxicity caused by arsenic.