PERIOSOFT碳纤维超声工作尖

随着现代科技的不断发展 ,超声波洁牙机已经广泛应用于口腔医学领域。作为口腔超声治疗设备的著名生产商 ,法国赛特力公司正致力于各种超声工作尖的研究、开发与生产。通过对超声工作尖的改进与创新 ,不断扩展超声洁牙机的临床应用范围。众所周知 ,虽然种植技术日趋成熟 ,但能否有效控制牙龈附着以上种植体表面的菌斑 ,依然是决定种植治疗远期成功率的一个重要因素。由于金属工作尖会划伤种植体表面 ,造成菌斑易于附着的粗糙面 ,所以一般不用于种植体的清洁。常用的种植体清洁工具为手用塑料器械。但受其形态及体积的限制 ,往往不能彻底去除…     

围手术期应用甲基强的松龙与地塞米松对脊髓型颈椎病髓内高信号转归及临床意义的比较

[目的]探讨围手术期应用甲基强的松龙(methylprednisolone,MP)与地塞米松(dexamethasone,DEX)对脊髓型颈椎病(cervical spondylotic myelopathy,CSM)术后MRI T2加权像髓内高信号(signal intensity,SI)转归及治疗效果的临床意义.[方法]回顾性研究2005年1月～2010年12月共109例存在颈脊髓MRI T2WI髓内高信号的CSM患者的临床资料,均采用前路颈椎间盘/椎体次全切除融合术(ACDF/ACCF),围手术期分别应用MP 56例(治疗组)、DEX 53例(对照组).分析患者性别、年龄、病程、术前JOA评分及髓内高信号类型等一般资料,对两组患者手术时间、术前和术后1、6及12个月时的髓内高信号强度比值、面积及神经功能改善率和并发症发生率进行比较.[结果]①两组患者一般资料的比较差异无统计学意义,但1型和2型髓内高信号患者间病程及术前JOA评分的比较差异有统计学意义.②两组患者术后髓内高信号强度比值及面积均下降,但高信号强度的比较在术后1个月时差异有统计学意义,高信号面积的比较在术后1、6个月时差异有统计学意义.③两组患者术后JOA评分均较术前增加,治疗组1、6个月时神经功能改善率均高于对照组,但术后12个月时差异无统计学意义.④两组患者并发症发生率比较差异无统计学意义.[结论]2型髓内高信号患者往往病程较长、术前神经功能减退明显.围手术期应用MP有利于减轻术后髓内高信号强度和面积,改善近期神经功能,且并不增加术后并发症,但两者术后12个月时的临床疗效相近.     

骨填充网袋治疗骨质疏松性椎体爆裂性骨折的临床应用

目的 评估骨填充网袋治疗骨质疏松性椎体爆裂性骨折的临床疗效及安全性。方法回顾性分析骨填充网袋治疗骨质疏松性椎体爆裂性骨折36例 。通过评估术前、术后3天、术后1年VAS评分、椎体前缘高度比及后凸Cobb角变化,观察骨水泥弥散及渗漏情况。结果35例手术顺利完成,骨水泥弥散良好,充盈满意,无渗漏,1例出现网袋松动。随访其术前、术后3天及1年VAS评分分别为:(8.35±1.32)、(2.01±1.12)、(1.98±1.34),椎体前缘高度比分别为:(47.3±9.4)%、(75.1±7.0)%、(74.1±7.1)%,Cobb角分别为:17.1°±7.3°、8.1°±5.4°、8.7°±5.5°,上述指标术后与术前相比差异有统计学意义(P<0.05),术后两者相比差异无统计学意义(P>0.05)。结论使用骨填充网袋治疗骨质疏松性椎体爆裂性骨折能够有效的缓解疼痛、纠正后凸,具有降低骨水泥外渗风险等优点。     

上消化道造影检查在胃癌术后早期的应用价值

目的 探讨上消化道造影在胃癌手术后早期的应用方法及价值.方法 对822例胃癌手术后早期应用上消化道造影检查及治疗患者的临床资料进行回顾性分析.结果 术后早期上消化道造影发现吻合口瘘、狭窄、动力性胃排空障碍等手术并发症,经及时治疗,大多数患者结局良好.结论 在胃癌术后早期进行上消化道造影检查能够及时、准确发现消化道外科并发症,指导临床制定方案,亦为快速康复外科提供循证医学证据.     

大鼠肾冷缺血再灌注损伤模型的建立

目的 建立大鼠肾冷缺血再灌注损伤(IRI)的模型.方法 封闭群SD大鼠24只,随机分为2组(n=12):A组(对照组),B组(实验组).A组切除右肾并游离左肾蒂,60 min后关闭腹腔切口.B组采用冷缺血再灌注模型,主要步骤:(1)冷灌注:右肾动脉插管对左肾原位灌注.通过右肾静脉插管将灌注液引流出体外,完成冷灌注后切除右肾,阻断左肾蒂.(2)冷缺血保存:将已充分游离的左肾牵至腹腔外,在自制保存袋中冷保存.(3)再灌注:60min后,去除保存袋,开放血流,再灌注左肾,左肾复位,缝合切口;2组大鼠均在术后24 h再次手术切除左.肾.肾组织进行光镜、电镜形态学检查,检测肾组织匀浆中超氧化物歧化酶(SOD)活力、丙二醛(MDA)含量,术前与术后24 h取血标本进行测定血尿素氮(BUN)、肌酐(Cr)评估肾功能.结果 (1)形态学检查(光镜与电镜超微结构):A组肾脏组织形态结构正常,B组损伤表现明显;(2)A组手术前后比较血浆BUN、Cr测定值差异均无统计学意义(P＞0.05).IR后的B组均高于术前,差异有统计学意义(P＜0.05);(3)IRI后A组肾组织匀浆SOD活力高于B组(P＜0.05),A组肾组织匀浆MDA含量测定值低于B组,差异有统计学意义(P＜0.05).结论 建立的模型要求条件简单、易行,可用于肾移植冷缺血再灌注损伤相关的研究;

Abstract：

Objective In this study,for studying IRI in kidney transplantation. ,we established the models of cold ischemia and reperfusion injury in rats. Methods Twenty four SD rats were randomly assigned to two groups:control (A) ,and experimental (B) group. Group A was only removed the right kidney. Cold ischemia reperfusion was performed as the follow-listed model in Group B. The main process of the model: ( 1) Perfusing left kidney: after resected the right kidney of the rat, one pipe was put in the remainder right renal artery to perfuse the left kidney. The perfusion flowed out through another pipe in the right renal vein. The blood vessels of left kidney were clipped after cold perfusion. (2) Cold ischemic conservancy : the operation table was leant to left side, and the left kidney was taken out of abdominal cavity then stored in a cold bag which was full of ice and water,but the vessels of that were intact. (3) Reperfusing left kidney: after 60 minutes, the clip was removed. Left kidneys of all rats in two groups were removed to be detected. Structure of the kidney was evaluated by light microscopy and electronic microscopy. Superoxide dismutase ( SOD) activity and malondialdehyde ( MDA) content in the renal tissues was examined,and the renal function was also assessed by determining the levels of blood urea nitrogen ( BUN) and serum creatinine (CR) before and 24 hours after operation. Results (1) Morphologic change (hematoxylin-eosin staining) :A normal morphology was observed by light microscopy and electon microscopy in group A.Significant injury was detected in group B. (2 ) In group A, there was not significant difference about BUN and CR between before and after operation (P ＞0. 05) ,but in Group B,those increased significantly at 24 hour after operation (P ＜0. 05). (3) Activity of SOD in renal tissues in group A was higher than those in group B (P ＜ 0. 05 ) , meanwhile, Content of MDA in group A was lower than those in group B ( P ＜0. 05 ).Conclusion The rat renal cold ischemia reperfusion model we established is feasible regardless of experimental conditions, and can be studied as the events following IRI in kidney transplantation.