新疆维吾尔族妇女外阴癌53例临床分析

目的: 探讨新疆维吾尔族妇女外阴癌的发病情况、临床表现、诊断治疗及预后.方法: 对新疆医科大学附属肿瘤医院1990年12月～2004年8月收治的85例外阴癌患者中53例维吾尔族患者的临床资料进行回顾性分析.平均发病年龄51.5岁;Ⅰ期3例,Ⅱ期 30例,Ⅲ期14 例,Ⅳ期 6例;45例行手术治疗,8例非手术治疗.结果:手术病人和非手术病人复发率比较差异有统计学意义(P<0.05).总的平均5年生存率为60.5%,各期生存率差异有统计学意义(P<0.05),Ⅰ、Ⅱ期生存率高于Ⅲ期.结论: 早期发现、早期诊断、早期治疗预后尤为重要.手术切除是外阴癌的主要治疗手段,手术方式的选择应个体化.     

Analysis of early treatment of 12 cases with congenital knee dislocation北大核心CSCD

Objective To investigate the curative effect of the Pavlik harness and polyester material casting bandage for the early treatment of congenital knee dislocation (CDK). Methods The clinical data of 12 patients (13 knees) with CDK treated in Provincial Hospital Affiliated to Shandong First Medical University from December 2011 and January 2019 were studied retrospectively. There were 3 males and 9 females. The median age at the initial visit was 3 days (1-29 days). Eleven patients had unilateral CDK, and 1 patient had bilateral CDK. There were 5 cases (5 knees) with dislocation and 7 cases(8 knees) with subluxation. Associated musculoskeletal anomalies were observed in 7 patients, which included developmental dysplasia of the hip (DDH) in 6 patients, bilateral DDH and right clubfoot in 1 patient. The Pavlik harness was applied to keep the knee in position for 1.5-2.0 months if passive flexion achieved 90°or more. If passive flexion was below 90°, the polyester material casting bandage was employed to increase knee flexion, and the bandage was changed once a week. After passive flexion reached 90°, the patient was treated with the Pavlik harness for 1.5-2. 0 months. Cases with DDH who worn the Pavlik harness were evaluated by ultrasonography in the follow - up period, and cases with clubfoot were treated with Ponseti polyester material casting bandages. Results Three children (4 knees) were directly fixed with Pavlik harness for 1.5-2. 0 months, 9 children (9 knees) were fixed with Pavlik harness for 1.5-2.0 months after 1-8 times (average 2. 9 times) of plaster fixation. No plaster and Pavlik harness complications were found during the treatment. Twelve patients were followed up for 29. 8 months on average (12.0 to 65. 0 months). Ten patients (11 knees) were rated excellent, and 2 patients (2 knees) were rated good. Conclusions The Pavlik harness and polyester material casting bandage for early treatment of CDK is simple, effective and safe. Associated musculoskeletal anomalies can also be corrected in the treatment process. The knee joint dislocation should be treated at first. © 2022 Chinese Journal of Applied Clinical Pediatrics. All rights reserved.     

木屑及其水解残渣快热解特性研究

生物质水解残渣中主要含有木质素和少量未水解完全的纤维素和半纤维素。研究了木屑以及水解残渣在氮气氛围下的TG和DTG曲线,着重探索残渣的裂解特性,并与木屑的热解特性作了比较,给出残渣热裂解一级平行动力学模型及其频率因子和活化能。研究表明:木质素是木质纤维素类热裂解产生焦碳的主要来源。随着升温速率的提高,生物质热裂解温度和速率明显提高。     

肘关节损伤系统临床研究

近年来,骨科的发展日新月异,新的理论、技术、器材以及对疾病的认识等方面都有了很大的进展。在创伤骨科方面,长骨骨干骨折的治疗已经不再是一个难题,但对关节内骨折的治疗还存在许多问题,主要原因是其损伤机制复杂、对患肢功能影响大、致残率高、治疗难度大以及并发症多等。尤其是肘关节损伤,由于其解剖结构复杂、功能要求高、损伤机制复杂,在临床上还存在许多悬而未决的难题,获得满意的疗效仍具有很大的挑战性。     

1例17α-羟化酶缺陷症患者股骨颈骨折的护理

先天性肾上腺增生症是一类常染色体隐性遗传病(CAH),主要由于肾上腺皮质激素生物合成过程中所必需的酶存在缺陷,致使皮质激素合成不正常[1].     

桡骨头骨折的手术内固定治疗

目的了解桡骨小头骨折手术内固定的治疗效果。方法对42例桡骨小头骨折手术内固定治疗的疗效进行随访分析。采用Mason骨折分类,和BrobergandMorrey肘功能评定方法,对骨折类型、手术固定方法等因素对预后的影响进行分析。结果本组42例获得随访,随访时间9个月～5年6个月。骨折均获得骨性愈合。按照BrobergandMorrey肘部评分标准进行判定,优11例,良21例,可7例,差3例,总的优良率为76%。微型钢板组的疗效优于单纯螺钉组(P=0.01)和克氏针组(P=0.04),单纯螺钉组和克氏针组之间的疗效差异不显著(P=1)。MasonⅡ型组的疗效明显优于MasonⅣ型组(P=0.03)。结论桡骨头骨折的内固定治疗能够改善肘关节的关节功能。对MasonⅡ型骨折和微型钢板固定方法的疗效较好。     

基因芯片在筛选宫颈癌相关基因中的应用研究

目的：通过研究宫颈癌组织和正常宫颈组织中差异表达的基因，筛选出与宫颈癌相关的基因群，并进一步研究其表达和初步功能。方法：以含2048条人类全长基因的cDNA基因表达谱芯片，检测3例宫颈癌标本和正常宫颈标本的基因表达谱，计算机分析比较两种组织中差异表达的基因。结果：3例宫颈癌差异表达基因分别有197条、429条和665条，共同差异表达的基因有64条。结论：宫颈癌同其他肿瘤一样，是多种基因结构和功能改变的结果，有关宫颈癌特异性相关基因及其作用有待进一步研究。     

踝关节骨折后的下胫腓骨性连接

目的研究下胫腓骨性连接对患者的症状和功能的影响,并探讨其对临床工作的启发。方法对14例术后出现下胫腓骨性连接的踝关节骨折的患者(共14踝)进行平均22.8个月(11～54个月)随访,采用Philips等踝关节临床评分系统对随访结果评分。结果主观症状:除3例患者主诉在长时间行走或劳动后有一过性酸痛外,其他病人均无不适主诉,所有患者均无明显生活或工作障碍;踝关节功能:跖屈平均为47.9°,较健侧差3.5°(0～10°),背伸平均为20°,较健侧差8.6°(0～20°);所有病人的X线片上均无明显骨性关节炎表现;Philips等踝关节临床评分平均为90.8分(82～98分),其中优71.4%,优良率100%。结论骨折后形成的下胫腓骨性连接通常不会引起明显的症状和功能障碍,一般无需进一步治疗。