天麻素联合利多卡因耳迷根穴位注射治疗特发性耳鸣的疗效分析

目的 探讨天麻素联合利多卡因耳迷根穴位注射治疗特发性耳鸣的疗效.方法 选取该院2012年5月-2015年12月收治的特发性耳鸣患者130例为研究对象,根据随机数字表法将其分为观察组(n=70)和对照组(n=60),其中对照组在基础治疗的基础上口服银杏叶制剂和金纳多口服片剂,观察组在对照组的基础上于耳迷根穴位注射利多卡因和天麻素.比较两组患者治疗前和治疗后耳鸣残疾量表(THI)评分、视觉模拟量表(VAS)评分、耳鸣响度、睡眠量表(SPIEGEL)评分、焦虑量表评分、抑郁量表评分和耳鸣分级的变化,评价两组的临床疗效.结果 治疗后,两组患者的THI评分、VAS评分、耳鸣响度、SPIEGEL评分、焦虑量表评分、抑郁量表评分和耳鸣分级较治疗前均明显降低,且治疗后观察组THI评分、VAS评分、耳鸣响度、SPIEGEL评分、焦虑量表评分、抑郁量表评分和耳鸣分级均低于对照组,两组比较均差异有统计学意义(P<0.05).对照组治疗的总有效率为58.3%,观察组治疗的总有效率为91.4%,两组总有效率比较差异有统计学意义(χ2=19.486,P<0.001).结论 耳迷根穴位注射天麻素和利多卡因可明显改善特发性耳鸣患者的生活质量,提高治疗特发性耳鸣患者的临床有效率.     

手术切除加局部烧灼治疗牙龈瘤36例报告

目的:探讨手术切除、局部烧灼保留牙齿治疗牙龈瘤的效果。方法:对36例病变区牙齿松动Ⅰ°以内的牙龈瘤采用手术切除后烧灼病变区牙周组织的治疗方法,并观察术后复发情况。结果:经6个月至4年随访,其中34例患者术后无肿瘤复发,有2例复发(P<0.05)。结论:采用手术切除瘤体后局部烧灼治疗牙龈瘤,其方法简单,疗效确定,可保存患牙。     

肺不张患者256例纤支镜结果分析

目的观察纤维支气管镜（纤支镜）对肺不张患者的病因诊断价值,并分析镜下表现特点。方法选择经我院临床及X线诊断为肺不张的患者256例为研究对象,按照年龄分为青年组、中年组和老年组。分析各组的病因分布特征,观察不同病因的镜下病变特点。结果中老年组占69.5%（178/256）,肺癌占56.3%（144/256）;青年组主要病因为炎症,占41.0%;肺癌中以鳞癌最常见,占57.6%（83/144）,镜下主要表现为管腔内新生物。结论纤支镜弥补了临床及X线无法进行病因诊断的缺陷,可依据镜下表现特点而明确诊断。     

重庆市民对种植义齿认知情况调查

目的:了解重庆市民对种植义齿的认知情况.方法:采用随机抽样方法抽取在我院进行常规体检的成年人共900名进行问卷调查,对调查结果进行统计学分析.结果:有13.9%的市民不知道什么是种植义齿,市民对于种植义齿最关注的问题是使用寿命和咬(牙)(合)的恢复,正在使用种植义齿的市民很少(5.7%),对于价格多数市民接受1000～3 000元/颗.结论:种植义齿的发展前景很好.     

经腹部超声及经阴道超声在子宫黏膜下肌瘤诊断中的应用

目的 评估经腹部超声及经阴道超声对小于3 cm的子宫黏膜下肌瘤的临床诊断价值.方法 收集西南医院妇产科经临床、剖腹探查或腹腔镜手术,术后病理证实为子宫黏膜下肌瘤患者124例,对其术前采取经腹部超声检查(TAUS)或经阴道超声检查(TVUS)结果 进行回顾性对比分析.结果 经腹部超声检查59例,诊断子宫黏膜下肌瘤35例,未检出24例,诊断符合率为59.3%;经阴道超声检查65例,诊断子宫黏膜下肌瘤59例,未检出6例,诊断符合率90.8%.两者差异有统计学意义(P<0.01).结论 TVUS对直径小于3 cm的子宫黏膜下肌瘤的检出具有明显优势.     

头花蓼对幽门螺杆菌粘附定植的影响

目的观察头花蓼水提物对幽门螺杆菌(Helicobacter pylori,H. pylori)粘附定植的影响。方法采用尿素酶活性比色法定量检测头花蓼水提物作用前后幽门螺杆菌尿素酶活性的影响;运用半固体布氏琼脂平板法检测不同浓度头花蓼对幽门螺杆菌鞭毛运动的影响;利用细胞爬片革兰染色观察不同浓度头花蓼作用后幽门螺杆菌在GES-1细胞表面粘附的变化并计算各组抑制率;采用Real-time PCR 技术检测头花蓼作用前后相关基因ureB、ureE、ureF、flaA、flaB、babA、alpA、alpB的mRNA转录水平。结果头花蓼水提物对幽门螺杆菌尿素酶活性具有抑制作用,抑制率为44.90±0.289。头花蓼浓度为1/2MIC、1/4MIC、1/8MIC分别作用后幽门螺杆菌菌膜晕圈直径显著小于对照组, 分别为(5.67±0.55)mm ,(8.5±0.50)mm ,(11.67±1.53)mm,差异有统计学意义(P<0.05);不同浓度头花蓼水提物均能抑制细菌粘附胃上皮细胞,各浓度组与对照组比较,差异有统计学意义(P<0.05)。头花蓼作用后,与对照组比较,下调了尿素酶结构基因ureB,尿素酶活性基因ureE、ureF、鞭毛相关基因flaB、flaA以及粘附素基因babA、alpA、alpB mRNA的转录水平,差异均具有统计学意义(P<0.05)。结论头花蓼对幽门螺杆菌具有明显的抑制作用,是通过抑制幽门螺杆菌尿素酶活性,减缓幽门螺杆菌的鞭毛动力,影响幽门螺杆菌对胃粘膜上皮细胞的粘附等方面发挥其抑菌作用。     

种植体联合牙半切剩余牙体共同支持下颌磨牙的三维有限元分析

BACKGROUND: Tooth hemisection contributes to preserving partial tooth structure and periodontal ligament that are able to reduce the resorption of alveolar bone. However, the traditional fixed partial denture (FPD) for dental restoration after hemisection jeopardizes the health of abutment tooth. Given this, the use of dental implant offers a new option for tooth restoration. OBJECTIVE: To analyze the feasibility of preserving a mandibular molar after hemisection by combining an inserted dental implant with the residual tooth by means of finite element analysis. METHODS: Based on the image data of a volunteer, three models with different ways of restorations were created: the model of combining implant and residual tooth after hemisection to support a molar crown (combined model), the model of implant to support a molar crown (implant model) and the model of FPD. Densities of two kinds of spongy bones were assigned respectively. Vertical load of 100 N was applied on the prosthesis. Biomechanical properties of different models were analyzed. RESULTS AND CONCLUSION: (1) Displacement of the tooth and implant: As the decrease of the density of spongy bone, displacements of the tooth and implant increased in the combined model. The implant displacement was higher in the combined model as compared with the implant model. For the combined model, the implant displacement was lower than that of the residual tooth. (2) Stress in the cortical bone: Stress in the cortical bone in models with low-density spongy bone was higher than that in the corresponding models with high-density spongy bone. Under the condition of high-density spongy bone, the highest values were obtained in the implant model, followed by the combined model and FPD model. Under the condition of low-density spongy bone, the highest values were obtained in the combined model, followed by the implant model and FPD model. (3) Strain in the spongy bone: Strain in the spongy bone in models with low-density spongy bone was higher than that in the corresponding models with high-density spongy bone. Under the condition of high-density spongy bone, the highest values were obtained in the FPD model, followed by the combined model and implant model. Under the condition of low-density spongy bone, the highest values were obtained in the combined model, followed by the FPD model and implant model. From the biomechanical point of view, it can be concluded that the combined use of an implant and residual molar after tooth hemisection is an acceptable treatment option under the condition of high-density spongy bone.     

醒脑开窍针刺法配合低分子肝素钙治疗进展性脑梗塞的疗效观察

目的：：对醒脑开窍针刺法联合低分子肝素钙治疗进展性脑梗塞的疗效进行临床评价。方法：对我院近年来收治的80例进展性脑梗塞患者进行随机平行分组,按照随机数字表随机分为治疗组与对照组各40例,两组患者均给予常规西医治疗方案(包括低分子肝素钙治疗),治疗组在此基础上加用中医醒脑开窍针刺法治疗,对两组患者治疗前、后的神经功能、日常生活能力评分等指标进行比较。结果：治疗14d后,治疗组NIHSS评分、BI指数均较同期对照组改善明显( P<0.05),且PT、APTT水平均较同期对照组明显升高( P<0.05),具有统计学意义。结论：醒脑开窍针刺法联合低分子肝素钙治疗进展性脑梗塞疗效理想,可显著促进神经功能恢复、提高生活能力,可能与其改善凝血功能机制有关。