双平面经直肠超声在诊断射精管囊肿中的应用价值

目的　探讨双平面经直肠超声在诊断射精管囊肿中的应用价值。方法　血精症、前列腺增生症患者与正常人均进行常规经腹和经直肠超声检查。发现有射精管囊肿者 ,测量射精管囊肿的三个径及对应前列腺的厚径 (D)、宽径 (W) ,并计算射精管囊肿的检出率和体积及前列腺的 D/ W值。结果　经直肠超声检查对射精管囊肿的检出率显著高于经腹超声检查 (15 .3%和 1.7% ;P<0 .0 1) ;血精症与前列腺增生症患者射精管囊肿的检出率显著高于正常人 (34.4 8%、 13.0 2 %和 2 % ;P<0 .0 1) ;增生前列腺 D/ W值与其内射精管囊肿体积呈正相关 [(0 .6 5± 0 .16 ) cm3和 (0 .6 7± 0 .2 7) cm3;r=0 .80 3,P<0 .0 0 1]。结论　射精管囊肿的发现对临床医师早期诊断前列腺及精囊疾病有重要意义。双平面经直肠超声正是能够早期发现射精管囊肿的一种实用性强而且准确度高的检查方法     

动态脑电图分级对昏迷患者预后的评估价值

目的观察动态脑电图检测对昏迷患者预后的评估价值。方法在98例不同病因昏迷患者急性期进行动态脑电图检测和格拉斯哥昏迷评分(GCS),随访患者3个月的预后,将动态脑电图检测和GCS评分结果与患者的预后结果进行相关分析。结果脑电图异常分级与GCS评分显负相关(r=0.751,P<0.001),脑电图分级为Ⅰ级:GCS为7.0±0.7,Ⅱ级时GCS为7.3±1.2,Ⅲ级时GCS为4.0±0.0,Ⅴ级时GCS为3.2±0.4;动态脑电图异常分级在死亡或植物状态组和残疾生存组与康复组比较差异均有统计学意义,GCS评分在死亡或植物状态组与康复组比较差异有统计学意义,而残疾生存组与康复组比较差异没有统计学意义。动态脑电图对植物状态和残疾生存患者预后的评估在敏感性(81.25%)、特异性(100%)和对预后评估的准确率(91.89%)方面均比GCS评分高。结论急性期动态脑电图检测对植物状态和残疾生存患者预后的评估有确切肯定的价值。     

CXCR4在人多发性骨髓瘤细胞的表达及对肿瘤细胞生物学行为的影响

目的　探讨CXCR4在多发性骨髓瘤 (MM)细胞上的表达和CXCR4 SDF 1α相互作用对MM肿瘤细胞生物行为及ICAM 1表达的影响。方法　采用免疫荧光标记和流式细胞仪表型检测分析MM细胞上CXCR4和粘附分子的表达 ;采用体外微孔隔离室实验进行SDF 1诱导的MM细胞迁移实验 ;ELISA方法测定血浆中sICAM 1的水平。结果　①新鲜MM细胞及MM细胞株不同程度地表达功能性CXCR4 [(5 0 .4± 2 7.3) % ],其表达水平与体外对SDF 1α诱导的迁移能力 [(2 3.6± 17.2 ) % ]密切相关 (P <0 .0 1) ;②SDF 1α可上调MM细胞表达粘附分子ICAM 1,ICAM 1的表达和可溶性ICAM 1的产生与CXCR4表达有一定相关性。结论　SDF 1α CXCR4对介导粘附分子的调节效应在MM细胞的生物行为中起重要的作用。     

新生儿家庭访视实习课教学方法探讨

产褥期是孕产妇死亡的高发时期[1],新生儿死亡中约2/3死于新生儿早期.新生儿家庭访视是社区护士为了保障产后妇女和新生儿的健康,在新生儿期对该家庭进行的定期的、以实施预防保健为主的护理服务活动,是护理本科生学习社区护理学必须掌握的知识与技能.我院2004年在<社区护理学>课程中增加了新生儿家庭访视实习课,取得较为满意的效果.现介绍如下.     

Study on the immunological safety of universal plasma in the Chinese population in vitro

Background

The prepared procedure for universal plasma in the Chinese population has been developed. However, the immunological safety with the level of antibodies, soluble immune complexes and complements is necessary to investigate.

胫骨平台粉碎性骨折复位后注射透明质酸钠的疗效观察

目的探讨胫骨平台粉碎性骨折,复位固定后关节腔内注射透明质酸钠疗效观察。方法对68例胫骨平台粉碎性骨折病人,切开复位内固定后,随机分为观察组和对照组,每组34例。观察组术后给予常规治疗护理、康复训练,术后第7天开始,膝关节腔内注射透明质酸钠2ml和1%利多卡因0.5ml,每周1次,共3次。对照组仅给予常规治疗护理、康复训练。两组病人术后3个月时,按Lysholm膝关节功能评分标准进行评分。结果经治疗后,观察组患者得分均高于对照组,两组得分差异有显著性(P<0.05)。结论胫骨平台粉碎性骨折,复位固定后关节腔内注射透明质酸钠能促进关节软骨愈合及功能恢复。     

Object detection in optical remote sensing images by integrating object-to-object relationships

ABSTRACT

In recent years, deep-learning-based methods for remote sensing image interpretation have undergone rapid development, due to the increasing amount of image data and the advanced techniques of machine learning. The abundant spatial and contextual information within the images is helpful to improve the interpretation performance. However, the contextual information is ignored by most of the current deep-learning-based methods. In this letter, we explore the contextual information by taking advantage of the object-to-object relationship. Then, the feature representation of the individual objects can be enhanced. To be specific, we first build a knowledge database which reveals the relationship between different categories and generate a region-to-region graph that indicates the relationship between different regions of interest (RoIs). For each RoI, the features of its related regions are then combined with the original region features, and the fused features are finally used for object detection. The experiments conducted on a public ten-class object detection dataset demonstrate the validity of the proposed method.     

抗心磷脂抗体在狼疮肾炎患者中的临床意义

背景:以往的研究表明,在系统性红斑狼疮及抗磷脂抗体综合征患者中,升高的抗心磷脂抗体滴度与血管血栓形成、血小板减少及反复流产的发生明显相关.但有关抗心磷脂在狼疮性肾炎患者中的临床意义的研究报道却不完全统一.目的:探讨抗心磷脂抗体在中国狼疮性肾炎患者中的阳性率及临床意义.设计:前瞻性单一样本的随访观察.单位:深圳市第四人民医院香蜜湖风湿病分院,广东医学院深圳风湿病研究所.对象:选择2001-03/2003-10于深圳市第四医院香蜜湖风湿病分院风湿科门诊就诊或住院的狼疮性肾炎患者97例.均符合美国风湿病学学会(ACR).1997年修订的狼疮性肾炎的诊断和分类标准.纳入对象均对检测项目知情同意.方法:记录患者入院后的临床资料和辅助检查结果.应用酶联免疫吸收法检测患者血清中的抗心磷脂抗体,阳性判断标准为测定值超过100 U/mL.大剂量口服强的松联合环磷酰胺静脉冲击治疗以诱导缓解,然后逐渐将强的松减量,将环磷酰胺换成硫唑嘌呤以维持疗效.同时使用其它药物控制可能合并的高血压、高血脂与关节痛等症状.每半年对纳入对象进行定期随访,记录狼疮性肾炎患者的临床资料及实验室检查结果,共3年.主要观察指标:患者的性别、年龄、系统性红斑狼疮病情活动指数,血栓形成、病理妊娠等临床表现及肾功能等实验室检查结果.结果:实验共纳入狼疮性肾炎患者97例,83例进入结果分析,14例脱落.在入选的97例患者中,其发病后被确诊时抗心磷脂抗体阳性者有38例(39%),高血压,血小板减少及雷诺现象在伴有抗心磷脂抗体阳性的狼疮性肾炎患者中更为常见.IgG型抗心磷脂抗体阳性狼疮件肾炎患者更易发生血管血栓形成:抗心磷脂抗体阳性狼疮性.肾炎患者更易发生流产、早产和死胎以及慢性肾功能不全恶化.结论:抗心磷脂抗体在狼疮性肾炎患者中的阳性率为39%,抗心磷脂抗体阳性的患者更易出现高血压,血小板减少及雷诺现象,抗心磷脂抗体阳件对预测狼疮性肾炎出现血管血栓形成、病理妊娠及慢性肾功能不全恶化可能有一定作用.     

Increased oxidative protection by high active vitamin E content and partial radiation crosslinking of UHMWPE

Vitamin E stabilization successfully improved long‐term oxidation resistance of wear‐resistant ultra‐high‐molecular‐weight polyethylene (UHMWPE) used for joint implants. Stabilization can be achieved by blending an antioxidant into the UHMWPE resin powder before consolidation and irradiation. Balancing the wear resistance and vitamin E content in the blend is the current challenge with this approach, because vitamin E hinders crosslinking of UHMWPE during irradiation, which decreases wear resistance. The vitamin E concentration in the blend is generally limited to less than 0.3 wt%. Wear‐ and oxidation‐resistant UHMWPE has been obtained previously by consolidating blends of pre‐irradiated UHMWPE powders (XPE) into an unmodified polyethylene matrix (PE), where the improvement in wear rate depended on the radiation dose and fraction of XPE. We hypothesized that increasing the vitamin E content in the unirradiated matrix would not compromise wear and would further improve the oxidative stability of XPE/PE blends. Pin‐on‐disk wear testing showed that the XPE/PE blends containing 0.1–1.0 wt% vitamin E in the matrix had comparable wear rates. We used an aggressive accelerated aging test in the presence of the pro‐oxidant squalene and oxidation induction time (OIT) test and found that higher amounts of vitamin E resulted in stronger oxidation resistance for XPE/PE blends. The mechanical strength and toughness of the blends were not affected by changing the vitamin E content in the matrix. Stabilizing UHMWPE with higher vitamin E content may extend the service life of UHMWPE implants. © 2017 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 36:1860–1867, 2018.