全文获取类型
收费全文 | 27236篇 |
免费 | 1483篇 |
国内免费 | 149篇 |
专业分类
耳鼻咽喉 | 299篇 |
儿科学 | 411篇 |
妇产科学 | 357篇 |
基础医学 | 3431篇 |
口腔科学 | 801篇 |
临床医学 | 1832篇 |
内科学 | 7115篇 |
皮肤病学 | 515篇 |
神经病学 | 1625篇 |
特种医学 | 819篇 |
外科学 | 4684篇 |
综合类 | 134篇 |
一般理论 | 1篇 |
预防医学 | 860篇 |
眼科学 | 661篇 |
药学 | 1735篇 |
1篇 | |
中国医学 | 69篇 |
肿瘤学 | 3518篇 |
出版年
2023年 | 156篇 |
2022年 | 320篇 |
2021年 | 540篇 |
2020年 | 303篇 |
2019年 | 385篇 |
2018年 | 514篇 |
2017年 | 423篇 |
2016年 | 531篇 |
2015年 | 509篇 |
2014年 | 672篇 |
2013年 | 816篇 |
2012年 | 1236篇 |
2011年 | 1384篇 |
2010年 | 756篇 |
2009年 | 628篇 |
2008年 | 1110篇 |
2007年 | 1257篇 |
2006年 | 1218篇 |
2005年 | 1257篇 |
2004年 | 1164篇 |
2003年 | 1220篇 |
2002年 | 1100篇 |
2001年 | 910篇 |
2000年 | 924篇 |
1999年 | 884篇 |
1998年 | 316篇 |
1997年 | 249篇 |
1996年 | 268篇 |
1995年 | 217篇 |
1994年 | 194篇 |
1993年 | 172篇 |
1992年 | 692篇 |
1991年 | 626篇 |
1990年 | 578篇 |
1989年 | 660篇 |
1988年 | 555篇 |
1987年 | 512篇 |
1986年 | 520篇 |
1985年 | 475篇 |
1984年 | 306篇 |
1983年 | 237篇 |
1982年 | 136篇 |
1980年 | 110篇 |
1979年 | 219篇 |
1978年 | 172篇 |
1977年 | 138篇 |
1974年 | 110篇 |
1971年 | 123篇 |
1970年 | 100篇 |
1969年 | 126篇 |
排序方式: 共有10000条查询结果,搜索用时 31 毫秒
141.
Satoshi Tobe Kazunori Yoshida Masahiro Yamaguchi Haruko Nishimura Masahito Kawata 《The Japanese Journal of Thoracic and Cardiovascular Surgery》2006,54(7):308-310
Papillary fibroelastoma (PFE) is a rare and benign cardiac tumor typically found on the valvular endocardium. In most cases,
PFE is identified incidentally on echocardiography or during cardiac surgery. The patient was a 73-year-old man who had been
treated for hepatocellular carcinoma for 5 years. On echocardiography, a 2.5-cm diameter mass was detected in the pulmonary
trunk just above the pulmonary valve. Through a transpulmonary arterial approach with cardiopulmonary bypass, the mass identified
on the commissure of the right and posterior pulmonary cusp was surgically excised together with the attached endocardium.
Despite the benign histology of PFE, lethal embolic events such as stroke, myocardial infarction, and pulmonary embolism are
reported in some cases. To prevent such complications, tumor identification and surgical excision are essential. 相似文献
142.
Cysts and tumors of the seminal vesicle are uncommon, and their coexistence is extremely rare. We report a case of multiple papillary tumors inside a seminal vesicle cyst associated with ipsilateral renal agenesis in a 17-year-old man. Surgical excision of the cyst and tumors was performed without any morbidity and histology revealed well differentiated papillary adenocarcinoma. 相似文献
143.
144.
145.
146.
Maki Kihara Tatsuya Sugita Yuichiro Nagai Naokatsu Saeki Ichiro Tatsuno Katsuyoshi Seki 《Gynecological endocrinology》2006,22(2):110-113
OBJECTIVE: We present a case of spontaneous ovarian hyperstimulation caused by pituitary gonadotroph macroadenoma, and include a review of the literature. CASE REPORT: A 27-year-old woman presented with irregular menstruation and bilateral multicystic enlargement of the ovaries. Serum estradiol (E(2)) levels were marginally elevated for the follicular phase but within the physiological range. Serum luteinizing hormone (LH) was extremely low, follicle-stimulating hormone (FSH) was normal, and prolactin (PRL) was high. Magnetic resonance imaging disclosed a pituitary macroadenoma. Immunohistochemical examination of the surgically removed adenoma showed intense reactivity for FSH and LH. After the operation, E(2), LH and PRL levels were normalized, the ovaries returned to a normal morphology, and regular menstrual cycles were resumed. CONCLUSION: A review of the literature showed that ovarian hyperstimulation caused by pituitary gonadotroph adenoma is not always accompanied by elevated FSH levels. High PRL and E(2) and low LH were reported in the majority of the cases, but E(2) may stay within the range observed in normal menstrual cycles. 相似文献
147.
Shigetoshi Yoshida Yasuo Sekine Yukio Saitoh Kazuhiro Yasufuku Takekazu Iwata Takehiko Fujisawa 《Annals of thoracic and cardiovascular surgery》2005,11(1):7-11
BACKGROUND: Although rabbits have often been used as an experimental model for the analysis of lung preservation, there are no reports of long-term survival after rabbit lung allotransplantation. The purpose of this study was to establish a lung allotransplantation model for the evaluation of acute lung rejection in the rabbit and to investigate the transplantation techniques in the rabbit. METHODS: Left unilateral lung allotransplantations were performed in 10 pairs of Japanese white male rabbits, weighing from 2.8 to 3.7 kg. Rabbits were divided into two groups. Group A rabbits (n=5) received Cyclosporine A (CsA) (20 mg/kg/day) orally for 5 days postoperatively, while Group B rabbits (n=5) received no CsA. All rabbits were sacrificed at the fifth postoperative day for histological examinations. RESULTS: Anastomoses of the pulmonary vein were achieved by using the atrial cuff technique. Satisfied blood flow was obtained in all arterial and venous anastomosis sites. Bronchial anastomosis was also well healed and all rabbits could maintain adequate spontaneous ventilation. In Group A, histopathology revealed that three cases were grade A0, one was grade A1 and the other was A2. In Group B, three cases lived for five days, and histopathology showed two cases were grade A2 and one case was grade A3. CONCLUSION: We established a left unilateral lung allotransplantation model in the rabbit and observed suppression of acute rejection of the transplanted lung by CsA. This study suggests that the rabbit is also an experimental model suited for the analysis of lung preservation as well as lung allotransplant rejection. 相似文献
148.
Results of low- and high-dose-rate interstitial brachytherapy for T3 mobile tongue cancer. 总被引:2,自引:0,他引:2
Naoya Kakimoto Takehiro Inoue Toshihiko Inoue Shumei Murakami Souhei Furukawa Ken Yoshida Yasuo Yoshioka Hideya Yamazaki Eiichi Tanaka Kimishige Shimizutani 《Radiotherapy and oncology》2003,68(2):123-128
PURPOSE: To evaluate the treatment results of low-dose-rate (LDR) and high-dose-rate (HDR) interstitial brachytherapy (ISBT) for T3 mobile tongue cancer. MATERIAL AND METHODS: Between 1974 and 1992, 61 patients with T3 mobile tongue cancer were treated with LDR ISBT using (192)Ir hairpins with or without single pins. In addition, between 1991 and 1999, 14 patients were treated with HDR ISBT. For nine patients treated with ISBT alone, the total dose was 59-94 Gy (median 72 Gy) within one week in LDR ISBT and 60 Gy/10 fractions/5 days in HDR ISBT. For 66 patients treated with a combination therapy of external beam radiotherapy (EBRT) and ISBT, the total dose was 12.5-60 Gy (median 30 Gy) of EBRT and 50-112 Gy (median 68 Gy) within 1 week in LDR ISBT or 32-60 Gy (median 48 Gy)/8-10 fractions/5-7 days in HDR ISBT. RESULTS: The 2- and 3-year local control rates of all patients were both 68%. The 2- and 3-year local control rates of patients treated with LDR ISBT were both 67%, and those with HDR ISBT were both 71%. The local control rate of patients treated with HDR ISBT was similar to those with LDR ISBT. CONCLUSIONS: ISBT for T3 mobile tongue cancer is effective and acceptable. The treatment result of HDR ISBT is almost similar to that of LDR ISBT for T3 mobile tongue cancer. 相似文献
149.
Masashi Hamada Ritsuko Hanajima Yasuo Terao Noritoshi Arai Toshiaki Furubayashi Satomi Inomata-Terada Akihiro Yugeta Hideyuki Matsumoto Yuichiro Shirota Yoshikazu Ugawa 《Clinical neurophysiology》2007,118(12):2672-2682
OBJECTIVE: Repetitive paired-pulse transcranial magnetic stimulation (TMS) at I-wave periodicity has been shown to induce a motor-evoked potential (MEP) facilitation. We hypothesized that a greater enhancement of motor cortical excitability is provoked by increasing the number of pulses per train beyond those by paired-pulse stimulation (PPS). METHODS: We explored motor cortical excitability changes induced by repetitive application of trains of four monophasic magnetic pulses (quadro-pulse stimulation: QPS) at 1.5-ms intervals, repeated every 5s over the motor cortex projecting to the hand muscles. The aftereffects of QPS were evaluated with MEPs to a single-pulse TMS, motor threshold (MT), and responses to brain-stem stimulation. These effects were compared to those after PPS. To evaluate the QPS safety, we also studied the spread of excitation and after discharge using surface electromyograms (EMGs) of hand and arm muscles. RESULTS: Sizes of MEPs from the hand muscle were enhanced for longer than 75min after QPS; they reverted to the baseline at 90min. Responses to brain-stem stimulation from the hand muscle and cortical MEPs from the forearm muscle were unchanged after QPS over the hand motor area. MT was unaffected by QPS. No spreads of excitation were detected after QPS. The appearance rate of after discharges during QPS was not different from that during sham stimulation. CONCLUSIONS: Results show that QPS can safely induce long-lasting, topographically specific enhancement of motor cortical excitability. SIGNIFICANCE: QPS is more effective than PPS for inducing motor cortical plasticity. 相似文献
150.
Motoaki Nakamura Dean F Salisbury Yoshio Hirayasu Sylvain Bouix Kilian M Pohl Takeshi Yoshida Min-Seong Koo Martha E Shenton Robert W McCarley 《Neuropsychopharmacology》2007,62(7):773-783
BACKGROUND: Overall neocortical gray matter (NCGM) volume has not been studied in first-episode schizophrenia (FESZ) at first hospitalization or longitudinally to evaluate progression, nor has it been compared with first-episode affective psychosis (FEAFF). METHODS: Expectation-maximization/atlas-based magnetic resonance imaging (MRI) tissue segmentation into gray matter, white matter (WM), or cerebrospinal fluid (CSF) at first hospitalization of 29 FESZ and 34 FEAFF, plus 36 matched healthy control subjects (HC), and, longitudinally approximately 1.5 years later, of 17 FESZ, 21 FEAFF, and 26 HC was done. Manual editing separated NCGM and its lobar parcellation, cerebral WM (CWM), lateral ventricles (LV), and sulcal CSF (SCSF). RESULTS: At first hospitalization, FESZ and FEAFF showed smaller NCGM volumes and larger SCSF and LV than HC. Longitudinally, FESZ showed NCGM volume reduction (-1.7%), localized to frontal (-2.4%) and temporal (-2.6%) regions, and enlargement of SCSF (7.2%) and LV (10.4%). Poorer outcome was associated with these LV and NCGM changes. FEAFF showed longitudinal NCGM volume increases (3.6%) associated with lithium or valproate administration but without clinical correlations and regional localization. CONCLUSIONS: Longitudinal NCGM volume reduction and CSF component enlargement in FESZ are compatible with post-onset progression. Longitudinal NCGM volume increase in FEAFF may reflect neurotrophic effects of mood stabilizers. 相似文献