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21.
We conducted a systematic review and meta-analysis to assess the outcomes and complications of naftopidil in treating elderly men with lower urinary tract symptoms secondary to benign prostatic hyperplasia and compared them with those administered with tamsulosin. A literature review was performed to identify the available randomised controlled trials concerning the comparison between naftopidil and tamsulosin for men with LUTS/BPH. We searched the following databases: the Cochrane Library Database, PubMed, Embase and Web of Science. Eleven publications involving 1,114 men (557 in the naf group and 557 in the tam group) were pooled in our analysis. We found no significant differences in the total IPSS, IPSS storage score, IPSS voiding score, quality of life index, peak urinary flow rate, average flow rate and post-void residual volumes. We assessed cardiovascular and sexual adverse events, acute urinary retention, surgical intervention, withdrawals due to any reason and withdrawals due to adverse events. The incidence of adverse events was similar among patients in naf and tam groups. In conclusion, naftopidil shared comparable efficacy and similar incidence of adverse events with tamsulosin and appears to be a promising agent for and alternative to tam. However, more prospective trials with high quality and long-term treatment duration are needed to verify this observation. 相似文献
22.
One of the hallmark characteristics of chronic diabetic wounds is the presence of biofilm‐forming bacteria. Bacteria encapsulated in a biofilm may coexist as a polymicrobial community and communicate with each other through a phenomenon termed quorum sensing (QS). Here, we describe the QS circuits of bacterial species commonly found in chronic diabetic wounds. QS relies on diffusion of signaling molecules and the local concentration changes of these molecules that bacteria experience in wounds. These biochemical signaling pathways play a role not only in biofilm formation and virulence but also in wound healing. They are, therefore, key to understanding the distinctive nature of these infections. While several in vivo and in vitro models exist to study QS in wounds, there has been limited progress in understanding the interplay between QS molecules and host factors that contribute to wound healing. Lastly, we examine the potential of targeting QS for both diagnosis and therapeutic intervention purposes. 相似文献
23.
Phase-Field-Based Axisymmetric Lattice Boltzmann Method for Two-Phase Electro-Hydrodynamic Flows 下载免费PDF全文
In this work, a novel and simple phase-field-based lattice Boltzmann (LB)
method is proposed for the axisymmetric two-phase electro-hydrodynamic flows. The
present LB method is composed of three LB models, which are used to solve the axisymmetric Allen-Cahn equation for the phase field, the axisymmetric Poisson equation for the electric potential, and the axisymmetric Navier-Stokes equations for the
flow field. Compared with the previous LB models for the axisymmetric Poisson
equation, which can be viewed as the solvers to the convection-diffusion equation,
the present model is a genuine solver to the axisymmetric Poisson equation. To test
the capacity of the LB method, the deformation of a single leaky or perfect dielectric
drop under a uniform electric field is considered, and the effects of electric strength,
conductivity ratio, and permittivity ratio are investigated in detail. It is found that
the present numerical results are in good agreement with some available theoretical,
numerical and/or experimental data. 相似文献
24.
25.
胸导管结扎预防食管癌术后乳糜胸的临床研究 总被引:6,自引:0,他引:6
目的 寻找减少或消除食管癌切除术后乳糜胸发生率的有效方法。方法 随机选取 45例 (A组 )食管癌患者 ,在食管癌切除加胃 食管残端吻合时 ,一期行预防性低位胸导管结扎术 (第 8胸椎水平以下 ) ;另 92例 (B组 )作对照组 ,仅做食管癌切除加胃 -食管残端吻合术。结果 两组患者在术后乳糜胸发生率 (A :1/ 45 ;B :9/ 92 ,P =0 0 3)、术后 48h胸腔引流量〔第 1个 2 4h :A :(2 5 4 33± 45 15 )ml,B :(4 93 6 1± 76 6 7)ml;第 2个 2 4h :A :(141 11± 2 5 5 3)ml,B :(32 3 39± 5 8 17)ml;P <0 0 5 )〕、3天内拨管率 (A :94 78% ;B :6 2 2 1% ,P =0 0 0 1)、并发症 (A :3/ 45 ,B :0 / 92 ,P =0 0 34)以及随访锁骨上淋巴结转移 (A :0 / 45 ,B :9/ 92 ,P =0 0 3)等方面有统计学意义。结论 术中行预防性低位胸导管结扎术可明显减少甚至消除食管癌患者术后乳糜胸的发生。 相似文献
26.
ffeSUtn6 Objectif Detenniner ie cusistence d' ostdoarthrite et d' ostdope dans la tste du femur. liChen 12 femmes (age moron 56 ans )atteintes d' ortdoorthrite de la hanche, on a Prdlevd la tste du femur durant la substitutiontotale de l' articulation de leur hanche. APrds das traitements, Ies tstes du femur furent studioes sons ie microscope dlectroniqued belang (soon ). ~flats to lesions ostdcorthritiques de differents degrds (azractdrithe per ba digs~nce du cartilage articulaire et d' hyp… 相似文献
27.
Porosity and accuracy of multiple-unit titanium castings 总被引:5,自引:0,他引:5
The objective of this investigation was to determine whether titanium could be used to cast reproducible multiple-unit dental restorations. A metal analog was machined to simulate preparations for a three-unit fixed partial denture. Castings were made with four different sprue designs at three temperatures. Marginal accuracy and porosity were evaluated. A total of 70 titanium castings were made with an argon/electric arc/vacuum/pressure casting machine. Ten castings were made in the conventional manner by use of gold-palladium alloy as a control to compare the marginal gap. The results revealed that the porosity was less when a large individual sprue (6-gauge) was used. It was also noted that the lower pattern burnout temperatures of 910 degrees C and 920 degrees C exhibited significantly smaller marginal gaps than did the higher temperature of 930 degrees C. 相似文献
28.
为了解分泌性中耳炎( O M E)对内耳听觉功能的影响,对 O M E220 例、304 耳分别进行纯音测听及声阻抗测定。结果表明,部分 O M E 患者骨导听阈升高,除造成传音性耳聋外,合并感音性耳聋( S N H L)为318% ,并随着病程延长, S N H L 发病率增高。提示应积极有效地治疗本病,应用扩血管及营养神经药物可防治 S N H L的发生。 相似文献
29.
蝶腭,筛前神经及鼻甲联合手术治疗常年性变应性鼻炎 总被引:1,自引:0,他引:1
在鼻内窥镜下为40例行蝶腭、筛前神经及鼻甲联合手术治疗常年性变应性鼻炎。结果:术后1月全部患者症状消失,显效100%;术后1年显效33例,占82.5%;有效6例,占15%,有效率为97.5%。提示该方法可广泛阻滞鼻腔副交感神经来源,降低鼻粘膜感觉灵敏部位敏感性以及感觉—副交感神经反射,破坏喷嚏反射弧的传入通路,使鼻粘膜对外界刺激敏感性下降,血管扩张减轻,腺体分泌减少,对常年性变应性鼻炎有明显疗效。 相似文献
30.
目的:探讨免疫细胞化学在细胞学诊断中的应用。方法:用常规技术和免疫细胞化学方法对70例胸腹水标本进行观察。结果:47例检出恶性和异型增生细胞,23例检测出良性和增生间皮细胞,CEA阳性率分别为55.3%,17.3%,差异显著。根据CEA、EMA、Keratin、Vimentin的表达有6例识别转移癌和增生间皮细胞。根据AFP、MG-7表达帮助确定6例肿瘤的原发灶。结论:免疫细胞化学能提高胸腹水细胞学诊断的准确性。 相似文献