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71.
Masatoshi Masuo Haruhito Takano Satoru Takamoto Jun Tanaka Shigehiro Kitamura Toshikazu Saito 《Circulation journal》2004,68(4):392-395
Pulmonary artery obstruction is a rare complication of acute thoracic aortic dissection. A 74-year-old woman was admitted to hospital with respiratory distress. Computed tomography scan showed right pulmonary artery occlusion and a thoracic aortic dissection of the Stanford A type. Lung perfusion scan revealed a defect in the entire right lung field. These findings mimicked acute pulmonary thromboembolism accompanying aortic dissection. On the other hand, pulmonary angiography revealed a round smooth defect of the right pulmonary artery, indicating an extrinsic compression. The patient finally died of cardiac tamponade. Autopsy disclosed that the right pulmonary artery was compressed by a hematoma in the adventitial space around the pulmonary artery. Such a mechanism of pulmonary artery obstruction caused by acute aortic dissection is unique, and is distinct from that caused by chronic non-dissecting aortic aneurysms, which themselves compress the pulmonary arteries. This complication inevitably follows aortic rupture; therefore, emergency operation to repair the dissected aorta must be performed to avoid the following catastrophic event. 相似文献
72.
73.
Takahiro Kametani Yuichiro Otani Toshikazu Ohigashi Tadahiko Kubo Tomohiko Sakuda Daisuke Furuta Yayoiko Ito Yuya Shigenobu Masaki Kakimoto Akihiro Kawahara Yuka Kikuchi Tomoki Kobayashi Daisuke Miyamori Nobusuke Kishikawa Keishi Kanno Masanori Ito 《Internal medicine (Tokyo, Japan)》2021,60(8):1311
We herein report a case of aortitis induced by granulocyte colony-stimulating factor (G-CSF) that coincided with lung injury, splenomegaly, and cutaneous manifestations during treatment for recurrent extraosseous mucinous chondrosarcoma. Computed tomography revealed large-vessel vasculitis, splenomegaly, and pulmonary interstitial changes. Treatment with prednisolone was successful. Because sarcoma is a rare disease, this case is valuable for showing clinicians that G-CSF preparations could cause aortitis regardless of the patient''s underlying diseases or therapeutic pharmacological backgrounds. 相似文献
74.
Kobayashi Toshikazu Omori Yuko Ono Yusuke Karasaki Hidenori Mizukami Yusuke Makino Naohiko Motoi Fuyuhiko Unno Michiaki Ueno Yoshiyuki Furukawa Toru 《Journal of gastroenterology》2021,56(6):581-592
Journal of Gastroenterology - Intraductal papillary mucinous neoplasm (IPMN) of the pancreas is categorized into four distinct types: the gastric, intestinal, pancreatobiliary, and oncocytic. Each... 相似文献
75.
76.
Takatsugu Yamamoto Mizue Tamura Toshikazu Hamauzu Akiko Nakayama Kazuo Kawasugi Masahide Kamakura Tadatoshi Kinoshita Yasushi Kuyama Masami Yamanaka Li-man Wang Masaki Sanaka Satoru Mineshita 《Journal of gastroenterology》1997,32(2):241-245
A 45-year-old man with intestinal Behçet's disease noticed an enlarged right cervical lymph node, and was diagnosed with diffuse large cell type, non-Hodgkin's lymphoma. The intrapelvic lymph tract was markedly deformed because of recurrent ileocecal ulceration, and conventional lymphoscintigraphy with a common tracer did not abolish the suspicion that lymphoma cells may have invaded the lymph nodes. Dynamic lymphoscintigraphy with a new tracer,99mtechnetium-diethylene triamine pentaacetic acid-human serum albumin, because of its high detection sensitivity, was very useful for excluding this suspicion, and for determining the clinical stage of lymphoma. Combination induction chemotherapy led to complete remission without any adverse effects, but subsequent supportive therapy with same protocol could not be completed because of progression of the intestinal lesions. Special management for the intestinal lesions, such as bowel rest, may be essential with chemotherapy for patients with intestinal Behçet's disease. 相似文献
77.
Yoshioka K Yoshida T Takakura Y Umekawa T Kogure A Toda H Yoshikawa T 《Metabolism: clinical and experimental》2005,54(4):488-491
To clarify whether polymorphisms G1704T and G82S of the RAGE gene were related to microalbuminuria, we performed a case-control study in Japanese type 2 diabetic patients. Polymorphisms G1704T and G82S of the RAGE gene were examined with genomic DNA obtained from 116 type 2 diabetic patients with microalbuminuria (urinary albumin/creatinine ratio between 30 and 300 mg/g of creatinine) (microalbuminuria group), and 232 patients with normoalbuminuria (urinary albumin/creatinine ratio <30 mg/g of creatinine) (normoalbuminuria group). The genotype distribution and T allele frequency of G1704T (9.9%) and S allele frequency of G82S (14.2%) in the microalbuminuria group did not significantly differ from those (T allele frequency, 8.4%; S allele frequency, 12.3%) in the normoalbuminuria group. There were no differences among the genotypes of G1704T and G82S of the RAGE gene regarding age, duration of diabetes, body mass index, glycosylated hemoglobin (HbA1c), blood pressure, and serum lipid levels. These data suggest that G1704T and G82S polymorphisms of the RAGE gene are not related to microalbuminuria in Japanese type 2 diabetic patients. 相似文献
78.
79.
Hepatic resection under in situ hypothermic hepatic perfusion 总被引:2,自引:0,他引:2
Kaiho T Tanaka T Tsuchiya S Yanagisawa S Takeuchi O Miura M Saigusa N Kitakata Y Miyazaki M 《Hepato-gastroenterology》2003,50(51):761-765
BACKGROUND/AIMS: Temporary inflow occlusion of the portal triad has been used frequently in hepatectomy to minimize bleeding. On the other hand, Pringle's maneuver produces ischemic-reperfusion injury especially in patients with underlying liver disease. METHODOLOGY: Thirty-seven cases of hepatic resections were performed with intermittent Pringle's maneuver (IP group; n = 17) and in situ hypothermic perfusion (CP group; n = 20). In the CP group, hepatic inflow was continuously occluded, and 4-degree Centigrade Ringer's lactate was administered by drip during resection. Hepatic outflow occlusion was not performed. RESULTS: All patients tolerated the procedures well. Cold perfusion technique significantly decreased both the times required and the blood loss in hepatectomy (p < 0.05). Serum hyaluronic acid levels gradually increased after the induction of hepatectomy and peaked 10 minutes after reperfusion in the both groups. Thereafter, it decreased and showed a significantly lower level in the CP group until 60 minutes after reperfusion (p < 0.05). Hepaplastin levels remained significantly higher in the CP group one week after operation (p < 0.05). CONCLUSIONS: Using the technique of in situ hypothermic perfusion, we can prolong the ischemic time safely with minimal systemic influence even in cases with underlying liver diseases. This may compare favorably with intermittent Pringle's maneuver in terms of reducing hepatic sinusoidal endothelial cell damage during hepatectomy and reperfusion. 相似文献
80.
Matsumoto K Morishita R Tomita N Moriguchi A Komai N Aoki M Matsumoto K Nakamura T Higaki J Ogihara T 《Heart and vessels》2003,18(1):18-25
Hepatocyte growth factor (HGF) is a unique growth factor with many protective functions. Previously, we demonstrated that
HGF stimulated growth of endothelial cells without replication of vascular smooth muscle cells (VSMC) and that angiotensin
(Ang) II significantly decreased local HGF production in VSMC. Moreover, we also reported that high glucose significantly
decreased local vascular HGF production. Therefore, we examined effects of Ang II blockade on vascular HGF expression and
endothelial injury in diabetic hypertensive rats. An angiotensin-converting enzyme inhibitor (quinapril) and an Ang II type
1 receptor antagonist (GA-0113) or vehicle was administrated to diabetic spontaneously hypertensive rats (SHR-DM), in whom
diabetes was induced by streptozotocin. Endothelial function was evaluated by the vasodilator response to acetylcholine, and
the expression of vascular HGF and its receptor, c-met, was examined by immunohistochemistry. Both quinapril and GA-0113 significantly
improved the vasodilator response to acetylcholine (P < 0.01), while vehicle did not as compared to untreated normotensive Wistar-Kyoto rats (WKY). We next examined the effects
of Ang II blockade on vascular HGF expression in SHR-DM. Importantly, the vascular HGF level was markedly decreased in SHR-DM
as compared to WKY, while Ang II blockade by quinapril or GA-0113 significantly increased positive staining for HGF in SHR-DM.
Similarly, staining of its specific receptor, c-met, was less in the blood vessels of SHR-DM as compared to WKY. In contrast,
Ang II blockade also significantly increased c-met production in SHR-DM. The present data demonstrated the improvement of
endothelial dysfunction by Ang II blockade in SHR-SM, accompanied by an increase in vascular HGF and c-met.
Received: June 7, 2002 / Accepted: September 21, 2002
Acknowledgments We wish to thank Rie Kosai and Keiko Yamaguchi for their excellent technical assistance. This work was partially supported
by grants from the Japan Health Sciences Foundation, a Grant-in-Aid from The Ministry of Public Health and Welfare, a Grant-in-Aid
for the Development of Innovative Technology, a Grant-in-Aid from Japan Promotion of Science, and through Special Coordination
Funds of the Ministry of Education, Culture, Sports, Science and Technology, the Japanese Government.
Correspondence to N. Tomita 相似文献