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排序方式: 共有206条查询结果,搜索用时 312 毫秒
161.
Probable Alzheimer disease: diagnosis with proton MR spectroscopy 总被引:25,自引:0,他引:25
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Intracranial hemorrhagic lesions: evaluation with spin-echo and gradient-refocused MR imaging at 0.5 and 1.5 T 总被引:4,自引:0,他引:4
Twenty patients with intracranial hemorrhage were examined with magnetic resonance (MR) imaging at 0.5 and 1.5 T within 2 hours on the two imagers for lesions less than 30 days old and within 24 hours for lesions older than 30 days. MR studies included T1- and T2-weighted spin-echo (SE) and T2*-weighted gradient-refocused (GR) pulse sequences at each field strength. The number of lesions identified and the characteristics (ie, signal intensity of the margin, body, and core) of each hemorrhagic lesion were assessed and compared by means of the three pulse sequences at each field strength. Lesion depiction and characterization were superior (P less than .01) at 1.5 T with T2-weighted SE sequences. Improved depiction and characterization of lesions 300 or more days old (P less than .01) accounted for this result. With the GR sequence, depiction and characterization were similar at both field strengths. The GR sequence did not provide significant additional information about hemorrhage at 1.5 T in this series, but it improved depiction and characterization of hemorrhage at 0.5 T. 相似文献
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GS Sandhu R Raju TK Bhattacharyya Shaktivardhan 《Medical Journal Armed Forces India》2008,64(1):43-45
Background
To predict the neonatal outcome in high risk obstetric cases by admission cardiotocography (CTG) testing.Methods
A total of 150 consecutive high risk obstetric patients meeting the inclusion criteria were subjected to admission CTG testing in this prospective study. The CTG tracing was categorized based on Royal College of Obstetricians and Gynaecologists (RCOG) criteria. Specific foetal and neonatal outcome measures were studied and correlated with the admission CTG testing.Result
Foetal distress during labour developed in 15% of patients with a normal test and in 73% of patients with an abnormal test. The admission test had a sensitivity of 66.7%, specificity of 93.3% and a positive predictive value of 53.3% for predicting an Apgar score < 5 at birth. Neonatal admission to neonatal intensive care unit was required in 1% of patients with a normal test and 33% of patients with an abnormal test (p <0.01).Conclusion
The result of admission cardiotocography testing could be used to identify patients likely to develop adverse foetal outcomes and help in optimal utilization of labour room resources.Key Words: Admission cardiotocography, High risk obstetrics, Labour management 相似文献168.
Kremmidiotis G; Lensink IL; Bilton RL; Woollatt E; Chataway TK; Sutherland GR; Callen DF 《Human molecular genetics》1999,8(3):523-531
Batten disease (juvenile neuronal ceroid lipofuscinosis) is a recessive
neurodegenerative disorder of childhood. The gene, CLN3, was recently
identified and found to encode a novel 438 amino acid protein of unknown
function. In order to gain insight into the function of the Batten disease
protein (CLN3p), we investigated its subcellular localization. Protein
constructs incorporating CLN3p fused to the green fluorescence protein or
an eight amino acid peptide tag were transiently expressed in fibroblasts,
HeLa and COS-7 cells. A juxtanuclear, asymmetric localization pattern was
observed that correlated with the Golgi apparatus in all three cell types.
However, a proportion of transiently transfected cells exhibited a punctate
vesicular distribution throughout the cytoplasm in addition to or without
the Golgi localization. In order to account for localization patterns
arising from intracellular protein transport disruption due to exaggerated
overexpression in transiently transfected cells, we isolated a stably
transfected cell line expressing only one copy of the CLN3 -GFP DNA
construct. Fluorescence and biochemical analyses using this cell line
demonstrated that CLN3p is an integral membrane protein that localizes
primarily in the Golgi apparatus. The functional implications of this
finding are discussed.
相似文献
169.
Yoen TK van der Linden Koop Bosscha Hubert A Prins Daniel J Lips 《World journal of gastrointestinal surgery》2015,7(8):145-151
AIM: To compare the safety of single-port laparoscopic cholecystectomies with standard four-port cholecystectomies.METHODS: Between January 2011 and December 2012 datas were gathered from 100 consecutive patients who received a single-port cholecystectomy. Patient baseline characteristics of all 100 single-port cholecystectomies were collected(body mass index, age, etc.) in a database. This group was compared with 100 age-matched patients who underwent a conventional laparoscopic cholecystectomy in the same period. Retrospectively, per- and postoperative data were added. The two groups were compared to each other using independent t-tests and χ2-tests, P values below 0.05 were considered significantly different.RESULTS: No differences were found between both groups regarding baseline characteristics. Operating time was significantly shorter in the total single-port group(42 min vs 62 min, P 0.05); in procedures performed by surgeons the same trend was seen(45 min vs 59 min, P 0.05). Peroperative complications between both groups were equal(3 in the single-port group vs 5 in the multiport group; P = 0.42). Although not significant less postoperative complications were seen in the single-port group compared with the multiport group(3 vs 9; P = 0.07). No statistically significant differences were found between both groupswith regard to length of hospital stay, readmissions and mortality. CONCLUSION: Single-port laparoscopic cholecystectomy has the potential to be a safe technique with a low complication rate, short in-hospital stay and comparable operating time. Single-port cholecystectomy provides the patient an almost non-visible scar while preserving optimal quality of surgery. Further prospective studies are needed to prove the safety of the single-port technique. 相似文献
170.
Curt Lofgren Nguyen X Thanh Nguyen TK Chuc Anders Emmelin Lars Lindholm 《Cost effectiveness and resource allocation : C/E》2008,6(1):1-16