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991.
992.
Anderson Rech MS Regis Radaelli MS Adriano M. De Assis PhD João R. Fernandes MS Aline Longoni PhD Magdolna M. Vozari‐Hampe PhD Ronei S. Pinto PhD Cristiane Matté PhD 《Muscle & nerve》2014,50(1):79-86
Introduction: In this study we examined oxidative stress and skeletal muscle damage resulting from acute strength, aerobic, or concurrent exercise in rats. Methods: The animals were divided into control (C), strength (SE), aerobic (AE), and combined (CE) exercise groups. They were euthanized at 3 different time‐points (6, 24, and 48 h) after acute exercise. Results: SE exercise rats had increased dichlorofluorescein oxidation at 6 h post‐exercise and decreased superoxide dismutase activity at all time‐points. Glutathione peroxidase activity and sulfhydryl levels were increased in the AE group at 48 h post‐exercise. Serum lactate dehydrogenase activity was increased in the SE and CE groups at 24 h and in the AE group at 48 h. Echo intensity was elevated at 24 h for all groups. Conclusions: Forty‐eight hours was sufficient for complete recovery from oxidative stress and muscle damage in the SE and CE groups, but not in the AE group. Muscle Nerve 50 : 79–86, 2014 相似文献
993.
Jennifer L. Goldstein PhD MS Gwen Dickerson BS Priya S. Kishnani MD Catherine Rehder PhD Deeksha S. Bali PhD 《Muscle & nerve》2014,49(5):775-776
Introduction: We have identified a large consanguineous Lebanese family with 5 individuals with severe childhood‐onset recessive sensory loss associated with deafness and variable optic atrophy. Methods: Autozygosity mapping was performed in all affected individuals, followed by whole‐exome sequencing (WES) in 2 individuals. Results: WES identified a homozygous missense mutation (c.916G>A, p.G306R) in the cerebral riboflavin transporter SLC52A2, recently shown to cause Brown‐Vialetto‐Van‐Laere syndrome (BVVLS), which is considered primarily a motor neuronopathy. Our patients have a phenotype distinct from BVVLS, characterized by severe progressive sensory loss mainly affecting vibration and proprioception that evolves to include sensorineural hearing loss in childhood, variable degrees of optic atrophy, and marked upper extremity weakness and atrophy. Treatment of 3 patients with 400 mg/day riboflavin over 3 months produced definite clinical improvement. Conclusions: Mutations in SLC52A2 result in a recognizable phenotype distinct from BVVLS. Early recognition of this disorder is critical, given its potential treatability. Muscle Nerve 50 : 775–779, 2014 相似文献
994.
Preoperative Prediction of Failure Following Two-Stage Revision for Knee Prosthetic Joint Infections
Fady Youssef SabryLeonard Buller BA Sarim AhmedAlison K. Klika MS Wael K. Barsoum MD 《The Journal of arthroplasty》2014
While two-stage revision is the gold standard for treatment of knee prosthetic joint infection (PJI), it is not without risk. The purpose of this study was to develop a tool to preoperatively predict the probability that a two-stage revision would fail to eradicate knee PJI. 3,809 surgical cases were retrospectively reviewed and data were collected from 314 charts. Overall, 105 (33.4%) cases failed to eradicate PJI using this procedure. Univariate analysis identified multiple variables independently associated with reinfection. Logistic regression was used to generate a model (bootstrap-corrected concordance index of 0.773) predicting failure of infection eradication. Preoperative knowledge of a high probability of failure may improve risk assessment, lead to more aggressive management, and allow for time to consider alternative therapies. 相似文献
995.
996.
The meaning of (quality of) life in patients with eating disorders: A comparison of generic and disease‐specific measures across diagnosis and outcome 下载免费PDF全文
997.
998.
Denise M. Gaughan ScD Paul D. Siegel PhD Michael D. Hughes PhD Chiung‐Yu Chang ScD Brandon F. Law MS Corey R. Campbell MS Jennifer C. Richards MS Stefanos F. Kales MD Marcia Chertok BS Lester Kobzik PhD Phuong‐son Nguyen PhD Carl R. O'Donnell PhD Max Kiefer MS Gregory R. Wagner MD David C. Christiani MD 《American journal of industrial medicine》2014,57(7):748-756
999.
Occupational injuries in Ohio wood product manufacturing: A descriptive analysis with emphasis on saw‐related injuries and associated causes 下载免费PDF全文
1000.
Agreement between upper respiratory diagnoses from self‐report questionnaires and medical records in an occupational health setting 下载免费PDF全文