全文获取类型
收费全文 | 8529篇 |
免费 | 400篇 |
国内免费 | 74篇 |
专业分类
耳鼻咽喉 | 106篇 |
儿科学 | 134篇 |
妇产科学 | 166篇 |
基础医学 | 962篇 |
口腔科学 | 171篇 |
临床医学 | 534篇 |
内科学 | 2295篇 |
皮肤病学 | 172篇 |
神经病学 | 491篇 |
特种医学 | 274篇 |
外科学 | 1629篇 |
综合类 | 19篇 |
一般理论 | 1篇 |
预防医学 | 228篇 |
眼科学 | 232篇 |
药学 | 444篇 |
中国医学 | 14篇 |
肿瘤学 | 1131篇 |
出版年
2024年 | 9篇 |
2023年 | 67篇 |
2022年 | 137篇 |
2021年 | 208篇 |
2020年 | 123篇 |
2019年 | 151篇 |
2018年 | 221篇 |
2017年 | 153篇 |
2016年 | 177篇 |
2015年 | 211篇 |
2014年 | 265篇 |
2013年 | 334篇 |
2012年 | 564篇 |
2011年 | 657篇 |
2010年 | 362篇 |
2009年 | 326篇 |
2008年 | 585篇 |
2007年 | 620篇 |
2006年 | 542篇 |
2005年 | 528篇 |
2004年 | 494篇 |
2003年 | 496篇 |
2002年 | 429篇 |
2001年 | 120篇 |
2000年 | 117篇 |
1999年 | 111篇 |
1998年 | 118篇 |
1997年 | 77篇 |
1996年 | 78篇 |
1995年 | 51篇 |
1994年 | 66篇 |
1993年 | 48篇 |
1992年 | 68篇 |
1991年 | 60篇 |
1990年 | 39篇 |
1989年 | 64篇 |
1988年 | 50篇 |
1987年 | 44篇 |
1986年 | 29篇 |
1985年 | 20篇 |
1984年 | 24篇 |
1983年 | 21篇 |
1982年 | 19篇 |
1981年 | 14篇 |
1980年 | 11篇 |
1979年 | 10篇 |
1978年 | 20篇 |
1977年 | 10篇 |
1975年 | 10篇 |
1974年 | 6篇 |
排序方式: 共有9003条查询结果,搜索用时 15 毫秒
91.
Nakamura T Ushiyama C Suzuki S Shimada N Sekizuka K Ebihara I Takahashi Y Tanaka A Koide H 《Nephron》2000,86(2):247
92.
Hisayuki Hiraiwa Minoru Hamazaki Satoru Tsuruta Hiroyoshi Hattori Jun-Ichi Mimaya Shirou Hasegawa Sumio Kohno Katsuhiko Aoki 《Pediatrics international》1998,40(6):604-607
Infantile hemangioendothelioma of the thymus is a rare disease. We describe a patient who developed a large anterior mediastinal mass, severe thrombocytopenia and massive pleural effusion at 1 month of age. Glucocorticosteroid and irradiation therapy had no effect on either the tumor size or clinical symptoms and the tumor was resected subtotally. Three months after the subtotal resection, the remaining tumor had almost disappeared and the symptoms had resolved. The patient has now been well for 1 year after surgery without evidence of recurrence. The tumor tissue was characterized by prominent vascular endothelial proliferation intermixed with a normal thymic structure, producing a picture consistent with that of an infantile hemangioendothelioma in the thymus, lmmunohistochemically, the tumor cells showed positive staining for vimentin, factor VIII and CD34. The DNA stemline and proliferative activity were examined by flow cytometry, which revealed a diploid stemline with a low growth fraction. DNA content and cell cycle analyses of the tumor tissue may be useful for predicting the biological behavior of the tumor. 相似文献
93.
Takeshi Hanagiri Ichiro Yoshino Mitsuhiro Takenoyama Tomoko So Hiroshi Fujie Satoru Imabayashi Ryozo Eifuku Takashi Yoshimatsu Toshihiro Osaki Ryoichi Nakanishi Yuji Ichiyoshi Akira Nagashima Kikuo Nomoto Kosei Yasumoto 《Cancer science》1998,89(2):192-198
Lung cancer-specific cytotoxic T lymphocytes (CTL) were induced by repeated stimulations of regional lymph node lymphocytes (RLNL) in lung cancer patients with either autologous or HLA-A-locus-matched tumor cells. To investigate the effect of interleukin-12 (IL-12), IL-12 was added during the stimulation of RLNL from HLA A24 / adenocarcinoma patients with either autologous tumor cells or HLA A24-positive adenocarcinoma cells (PC-9) in combination with, or instead of interleukin-2 (IL-2), and then the cytotoxic activity, cytokine production and populations of the lymphocyte subsets were examined. The addition of IL-12, or the substitution of IL-2 by IL-12 was found to enhance the cytotoxic activity and the cytokine production (IFN-γ, GM-CSF) of the CTL as compared with IL-2 alone. The cytotoxic activity and cytokine production were both partially inhibited by anti-MHC-class I monoclonal antibody. The CTL thus induced by IL-12 had a higher proportion of CD3+ /CD56+ cells than the CTL induced with IL-2 alone. The positively selected CD8+ /CD56– lymphocytes showed PC-9-specific cytotoxic activity, because the population did not show any cytotoxicity to K562 or A549 (HLA-A26/A30). However, the CD3+ /CD56+ lymphocytes were cytotoxic to both PC-9 and K562. In conclusion, IL-12 is considered to be a useful cytokine for both the induction of lung-cancer specific CTL and the augmentation of non-MHC-restricted cytotoxicity against tumor cells, and may be applicable for adoptive immunotherapy using CTL. 相似文献
94.
Dihydropyrimidine dehydrogenase activity in 150 healthy Japanese volunteers and identification of novel mutations. 总被引:4,自引:0,他引:4
95.
96.
97.
98.
99.
Satoru Kudose Dominick Santoriello Hanna Debiec Pietro A. Canetta Andrew S. Bomback M. Barry Stokes Ibrahim Batal Pierre Ronco Vivette D. D’Agati Glen S. Markowitz 《Kidney international》2021,99(1):247-255
- Download : Download high-res image (415KB)
- Download : Download full-size image