全文获取类型
收费全文 | 12407篇 |
免费 | 1053篇 |
国内免费 | 207篇 |
专业分类
耳鼻咽喉 | 133篇 |
儿科学 | 425篇 |
妇产科学 | 286篇 |
基础医学 | 973篇 |
口腔科学 | 211篇 |
临床医学 | 1735篇 |
内科学 | 3091篇 |
皮肤病学 | 260篇 |
神经病学 | 1067篇 |
特种医学 | 344篇 |
外科学 | 2684篇 |
综合类 | 32篇 |
预防医学 | 628篇 |
眼科学 | 408篇 |
药学 | 416篇 |
中国医学 | 9篇 |
肿瘤学 | 965篇 |
出版年
2023年 | 163篇 |
2022年 | 97篇 |
2021年 | 270篇 |
2020年 | 198篇 |
2019年 | 197篇 |
2018年 | 291篇 |
2017年 | 304篇 |
2016年 | 359篇 |
2015年 | 297篇 |
2014年 | 432篇 |
2013年 | 575篇 |
2012年 | 488篇 |
2011年 | 485篇 |
2010年 | 466篇 |
2009年 | 537篇 |
2008年 | 471篇 |
2007年 | 450篇 |
2006年 | 483篇 |
2005年 | 426篇 |
2004年 | 371篇 |
2003年 | 325篇 |
2002年 | 299篇 |
2001年 | 340篇 |
2000年 | 322篇 |
1999年 | 316篇 |
1998年 | 242篇 |
1997年 | 267篇 |
1996年 | 375篇 |
1995年 | 308篇 |
1994年 | 243篇 |
1993年 | 150篇 |
1992年 | 249篇 |
1991年 | 250篇 |
1990年 | 166篇 |
1989年 | 221篇 |
1988年 | 183篇 |
1987年 | 160篇 |
1986年 | 168篇 |
1985年 | 148篇 |
1984年 | 165篇 |
1983年 | 120篇 |
1982年 | 98篇 |
1981年 | 90篇 |
1980年 | 104篇 |
1979年 | 80篇 |
1978年 | 87篇 |
1977年 | 56篇 |
1976年 | 72篇 |
1975年 | 59篇 |
1972年 | 52篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
51.
Marie-Francoise Dresse Michele David Heather Hume Herve Blanchard Pierre Russo Nicolas Van Doesberg Georges E. Rivard 《Pediatric hematology and oncology》1991,8(4):329-334
The Kasabach-Merritt syndrome is characterized by thrombocytopenia and localized coagulopathy associated with a hemangioma. Most techniques applied to eradicate the tumor or accelerate its involution (surgery, radiation therapy, embolization) are invasive and require transfusion of large amounts of blood products. In some cases, medical treatment is the only alternative. Efficacy of steroids and antifibronolytic agents has already been described, but even this approach is associated with the administration of blood products. We report two cases of infants with Kasabach-Merritt syndrome associated with cardiac and hepatic hemangiomas. At admission, both had signs of cardiac failure. They were successfully treated with prednisone and epsilon-aminocaproic acid (EACA). Blood products were not required once the diagnosis was made. These observations have important implications for the management of patients with Kasabach-Merritt syndrome because they show that even in severe cases blood transfusions can be avoided by the use of prednisone and EACA. 相似文献
52.
A randomized controlled trial of sedation in the critically ill 总被引:2,自引:0,他引:2
LYNN PARKINSON RSCN JULIE HUGHES RSCN REA GILL MSc IMOGEN BILLINGHAM BM FRCA JANE RATCLIFFE MB ChB FRCP & IMTI CHOONARA MD MRCP 《Paediatric anaesthesia》1997,7(5):405-510
A randomized controlled trial comparing: a) a combination of oral chloral hydrate and promethazine to b) a continuous intravenous midazolam infusion, for maintenance sedation in critically ill children, was carried out. The level of sedation was assessed four hourly using a specifically devized sedation scale. Forty-four children entered the study of whom two were subsequently excluded. The number of satisfactory assessments (desired and actual levels of sedation equal) was significantly greater in the chloral hydrate and promethazine group (Chi-squared P <0.01; confidence intervals of the difference 0.06 to 0.20). The number of assessments at level 5 on the sedation scale (patient restless/distressed) was significantly greater in the midazolam group (Chi-squared P <0.05). The total number of satisfactory assessments in the two groups were only 61 and 48% respectively, suggesting that sedation can be considerably improved. Chloral hydrate and promethazine are more effective than midazolam as maintenance sedation in critically ill children. It is possible to prospectively study the efficacy of sedative drugs in critically ill children. 相似文献
53.
Robert G. Sammut MB BCh BAO MRCPsych 《Journal of advanced nursing》1997,26(1):20-24
A survey by questionnaire was carried out to examine the level of nursing staff satisfaction with the acute psychiatric services. Comparisons were made between views of older psychiatric hospitals and newer district general hospital units, and before and after the closure of Friern Barnet Hospital, London, England when the service was reorganized to include fewer beds. The importance of nurses having their say is emphasized, and areas in which improvements can be made are suggested. 相似文献
54.
An operating theatre fire and the steps taken to deal with it are described; the difficulties encountered in evacuating anaesthetised patients are highlighted. Measures which might be taken to prevent recurrence of these problems, and recommendations on the institution of fire drills for the safety of patients and staff are given. 相似文献
55.
Ralls PW; Johnson MB; Kanel G; Dobalian DM; Colletti PM; Boswell WD Jr; Radin DR; Halls JM 《Radiology》1986,161(2):451-454
FM sonography - a signal-processing technique that uses frequency and phase information as well as amplitude data - shows promise in evaluation of patients with diffuse liver disease. In a prospective blinded review of 37 patients with biopsy-proved liver disease and 42 healthy volunteers, FM sonography was clearly superior to traditional amplitude-based (AM) sonography in distinguishing healthy from diseased subjects. Statistically significant differences were seen in accuracy (FM, 98.7%; AM, 84.8%), sensitivity (FM, 97.3%; AM, 70.3%), and negative predictive value (FM, 97.7%; AM, 78.8%). Our data also suggest that current FM sonographic techniques cannot differentiate among histologic findings associated with different hepatic parenchymal abnormalities. It is unclear, therefore, whether FM imaging can reduce the numbers of patients who require biopsy for diagnosis or the frequency of biopsy procedures in patients with known disease. 相似文献
56.
A Boido F Novelli F Savelli F Sparatore S Russo W Filippelli V Susanna E Marmo 《Il Farmaco; edizione pratica》1989,44(3):279-301
Thirteen amidoderivatives of 3-methyl-3,4-dihydro-6-R-benzo-1,2,4-triazin-3-yl-acetic acids and of 3-methyl-3,4-dihydro-pyrido [3,2-e]/[3,4-e]-1,2,4-triazin- 3-yl-acetic acids were prepared and submitted to a wide pharmacological screening. The dihydrobenzotriazine and dihydropyridotriazine moieties were endowed with a wide pharmacogenic capacity; in fact, several compounds exhibited high antiinflammatory [(I c), (I d), (II d), (V f), (VI f)], diuretic [(I f), (I g), (I h)] and antihypertensive activities [(I d), (III d)], as well as minor effects on the C.N.S. 相似文献
57.
Terry Kwong MB BS FRACP Senior Fellow Elsa Valderrama MD Assistant Professor of Pediatric Pathology Carole Paley MD Assistant Professor of Pediatrics Norman Ilowite MD Associate Professor of Pediatrics 《Seminars in arthritis and rheumatism》1994,23(6)
Childhood sarcoidosis is a rare disorder with protean manifestations. The case of a child with prolonged fever, hepatosplenomegaly, pancytopenia, and systemic necrotizing vasculitis manifesting as fever, rash and skin infarctions, digital pregangrene, and foot drop is reported. This is the first case of systemic necrotizing vasculitis reported in sarcoidosis. The fulminant course of the disease required treatment with intravenous pulsed cyclophosphamide and high doses of corticosteroids. The spectrum of vasculitis in childhood and adult sarcoidosis is reviewed. 相似文献
58.
From mid-October 1989 to mid-July 1990 all newly admitted residents to Bury Local Authority Residential Homes were comprehensively medically screened. In a series of 100 residents eight had early Parkinson's disease (six of them hitherto undiagnosed). Seven showed evidence of Vitamin C deficiency. Of the seven showing evidence of deficiency, four suffered from early Parkinson's disease. Of the 93 without evidence of Vitamin C deficiency only four had Parkinson's disease. This indicates a significantly higher prevalence of Parkinson's disease in the group with Vitamin C deficiency (P less than 0.001 using Fisher's exact). 相似文献
59.
60.