Growth,yield and elemental status of rice (<Emphasis Type="Italic">Oryza sativa</Emphasis>) grown in fly ash amended soils

Fly ash (FA) from coal in Orissa (India) was used for amending soil at levels equivalent to 0, 1, 2.5, 5, 10 and 15 metric tons per ha in which, rice was grown and elemental residues of amended soil and plant parts were enumerated. FA amendments caused significant improvement in soil quality and germination percentage of rice seeds. Growth (shoot length, leaf area and pigment composition) and yield (panicle length, seeds per panicle, seed weight and yield per plant) of rice increased with an increase in FA amendments. Catalase and peroxidase activities of young leaves increased initially in plants cultivated at lower FA levels but declined sharply at higher FA levels while the protein content of seeds improved at higher FA levels. Sodium content of rice-roots did not change with FA amendments but the contents of K, P, Mn, Ni, Co, Pb, Zn, Cu, Cr, and Cd showed a progressive increase. Seeds of plants grown in FA amended soils accumulated Cu, Pb, Cr and Cd in amounts below allowable limits. Based on the data obtained we found that flooded-rice soil amended at 10 metric tons FA per ha level of FA not only improved the physical properties of the soil but also contributed to better growth and yield of rice.     

Current scenario of 1,4-diazepines as potent biomolecules--a mini review

The aim of this review is precisely to give a comprehensive account of the large volume of work carried out on 1,4-diazepines regardless of the degree of unsaturation in the diazepine system. This review mainly emphasizes recent work on the diazepines also including earlier work.     

SRY-negative 46,XX male with normal genitals, complete masculinization and infertility

XX maleness is a rare syndrome with a frequency of 1 in 20,000-25,000 males. XX males exist in different clinical categories with ambiguous genitalia or partially to fully mature male genitalia, in combination with complete or incomplete masculinization. In this study, we report a case of SRY-negative XX male with complete masculinization but infertility. The patient had fully mature male genitalia with descended but small testes and no signs of undervirilization. PCR analysis for SRY, ZFY, Amelogenin, AZFa, AZFb, AZFc genes, a pair of primers from heterochromatic region and six Y-STRs showed the absence of any Y-chromosome-derived material. Absence of SRY gene was confirmed by three independent PCRs for each of two sets of primers covering an increasing length of the gene. Sequence analysis of the coding regions of SOX9 and DAX1 genes did not reveal any mutation. Real-time PCR assay revealed normal copy number for SOX9 gene. Microsatellite analysis showed no evidence of 17q (SOX9 gene) or 22q duplication. Genotyping with X-STRs ruled out the possibility of any deletion on X chromosome. Development of the male phenotype in the absence of SRY probably resulted from the loss of function mutation in some unknown sex-determining gene, which normally inhibits the male pathway, or from a gain of function mutation in a gene downstream to SRY in male pathway.     

The epidemiology and clinical features of portal vein thrombosis: a multicentre study

Aliment Pharmacol Ther 2010; 32: 1154–1162

Summary

Background Reliable epidemiological data for portal vein thrombosis are lacking. Aims To investigate the incidence, prevalence and survival rates for patients with portal vein thrombosis. Methods Retrospective multicentre study of all patients registered with the diagnosis of portal vein thrombosis between 1995 and 2004. Results A total of 173 patients (median age 57 years, 93 men) with portal vein thrombosis were identified and followed up for a median of 2.5 years (range 0–9.7). The mean age‐standardized incidence and prevalence rates were 0.7 per 100 000 per year and 3.7 per 100 000 inhabitants, respectively. Liver disease was present in 70 patients (40%), malignancy in 27%, thrombophilic factors in 22% and myeloproliferative disorders in 11%. Two or more risk factors were identified in 80 patients (46%). At diagnosis, 65% were put on anticoagulant therapy. Thrombolysis, TIPS, surgical shunting and liver transplantation were performed in 6, 3, 2 and 8 patients, respectively. The overall survival at 1 year and 5 years was 69% and 54%. In the absence of malignancy and cirrhosis, the survival was 92% and 76%, respectively. Conclusions The incidence and prevalence rates of portal vein thrombosis were 0.7 per 100 000 inhabitants per year and 3.7 per 100 000 inhabitants, respectively. Concurrent prothrombotic risk factors are common. The prognosis is variable and highly dependent on underlying disease.     

Photoaggravated hand and foot psoriasis

The majority of patients with psoriasis benefit from ultraviolet radiation exposure, but psoriasis can deteriorate on exposure to sunlight in some people. We report a patient with longstanding palmoplantar psoriasis that showed an unusual evolution into photoaggravated psoriasis, with change of distribution from the palmar to the dorsal aspect of the hands, and confirmation by photoprovocation with solar-simulated radiation. The onset of photosensitivity should be suspected in patients with hand and foot psoriasis showing a similar change in distribution.     

Laugier-Hunziker syndrome: A case report and review of the literature

Laugier-Hunziker syndrome (LHS) is a rare acquired disorder characterized by diffuse macular hyperpigmentation of the oral mucosa and, at times, longitudinal melanonychia. Although LHS is considered a benign disease with no systemic manifestations or malignant potential, it is important to rule out other mucocutaneous pigmentary disorders that do require medical management. Prompt clinical recognition also averts the need for excessive and invasive procedures and treatments. To date, only four cases have been reported in the United States. We present a 77-year-old man who had clinical features typical of LHS and we then provide a review of the literature on LHS and its mimickers.     

Novel 2-Aminobenzamides as Potential Orally Active Antithrombotic Agents

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