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141.
142.
White cell (WBC) reduction of blood components has been receiving increased attention as a way of reducing transfusion-related complications such as WBC-associated HLA alloimmunization and transmission of cell-associated viral diseases. Currently available filters are limited to removing approximately 3 log10 (99.9%) of WBCs from red cells (RBCs). The performance of two experimental filters that were designed to remove 6 log10 WBCs from fresh RBCs during component preparation was evaluated. Both filters were able to meet this objective in less than 40 minutes with RBC losses of less than 15 percent under nonoptimized conditions. Filtered RBCs showed storage parameters within the normal range over a 42-day period. The use of these filters, if combined with a sterile docking device or if incorporated into a collection set, should provide the means to supply highly WBC-reduced RBCs with a normal shelf life. 相似文献
143.
144.
Andreas RR Weiss Christina Hackl Yorick Soeder Hans J Schlitt Marc-H Dahlke 《World journal of gastroenterology : WJG》2016,22(14):3869-3874
Esophageal reconstruction can be challenging when stomach and colon are not anatomically intact and their use as esophageal substitutes is therefore limited. Innovative individual approaches are then necessary to restore the intestinal passage. We describe a technique in which a short stump of the right hemicolon and 25 cm of ileum on a long, non-supercharged, fully mobilized ileocolic arterial pedicle were used for esophageal reconstruction to the neck. In this case, a 65 year-old male patient had accidentally indigested hydrochloric acid which caused necrosis of his upper digestive tract. An emergency esophagectomy, gastrectomy, duodenectomy, pancreatectomy and splenectomy had been performed in an outside hospital. A cervical esophagostomy and a biliodigestive anastomosis had been created and a jejunal catheter for enteral feeding had been placed. After the patient had recovered, a reconstruction of his food passage via the left and transverse colon failed for technical reasons due to an intraoperative necrotic demarcation of the colon. Our team then faced the situation that only a short stump of the right hemi-colon was left in situ when the patient was referred to our center. After intensified nutritional therapy, we reconstructed this patient's food passage with the right hemicolonapproach described herein. After treatment of a postoperative pneumonia, the patient was discharged from hospital on the 26 th postoperative day in a good clinical condition on an oral-only diet. In conclusion, individual approaches for long-segment reconstruction of the esophagus can be technically feasible in experienced hands. They do not always require arterial supercharging or free intestinal transplantation. 相似文献
145.
146.
一般认为,缺铁是美国等地区最为常见的营养缺乏病之一,尤其在行经期妇女中更为显著(Monsen et al,1967,Scott et al 1967)。一些学者(Hunding et al.1981,Clement etal.1982)已报告运动员存在相对低水平的铁储备,从而使人推测运动训练是否会促进体内铁储备释出的问题。近年来,越来越多的人参加长跑锻炼,特别是妇女参加长跑的人数日趋增多。可是对女长跑运动员的铁储备水平了解甚少。本文目的是通过对业余女子长跑运动员铁储备和血液指标的检测,了解她们的铁储备状况,并与一般女子的结果进行了比较。 相似文献
147.
A 9-yr-old female presented with a Wilm's tumor and a coagulopathy consistent with von Willebrand's disease. Factor VIII procoagulant activity (VIII C), factor VIII related antigen (VIIIR:Ag), and von Willebrand factor activity (VIII:vWf) were decreased. There was no evidence for a circulating inhibitor of the factor VIII molecular complex. von Willebrand's antigen II (vW AgII), which is deficient in hereditary von Willebrand's disease, was decreased below detectable levels in this patient. The coagulation studies, VIIIR:Ag, and vW AgII levels returned to normal following therapy of the Wilm's tumor. Wilm's tumor must be included as one of the malignancies associated with acquired von Willebrand's disease. Immunofluorescent studies of the tumor specimen showed normal endothelial staining of VIIIR:Ag by semiquantitative techniques and a lack of specific tumor adsorption of VIIIR:Ag The presence of normal amounts of tissue VIIIR:Ag has not previously been demonstrated in acquired von Willebrand's disease. Since we failed to demonstrate an inhibitor in the plasma in this patient, the etiology of the acquired von Willebrand's disease in this patient appears to differ from other cases of acquired von Willebrand's disease. The finding that vW AgII is decreased in this patient, similar to that reported in hereditary von Willebrand's disease, supports the close association of vW AgII to VIIIR:Ag, even though they are immunologically and biochemically distinct. 相似文献
148.
约5%的孕妇患有无症状性尿道感染。如果在怀孕的最初三月发现菌尿症而未予根治,可能约25%的人在后三个月或产褥期将继发急性肾盂肾炎。若在无症状阶段给予充分的治疗,可使并发症的危险减至最低程度。最近的临床研究表明,单剂量抗菌剂治疗 相似文献
149.
Five women suspected of having puerperal ovarian vein thrombosis (POVT) were examined with either computed tomography (CT) (five patients), ultrasonography (US) (three patients), magnetic resonance (MR) imaging (one patient), or a combination of these modalities. CT findings included tubular retroperitoneal mass (five patients), periuterine mass (four patients), enlarged uterus (four patients), fluid in the uterus (five patients), central ovarian vein thrombus (four patients), inferior vena cava thrombus (one patient), right hydroureter (one patient), and right ureteral compression (one patient). US findings were similar to CT findings except for an inability to demonstrate the right hydroureter and ureteral compression. MR imaging demonstrated the retroperitoneal mass and central ovarian vein thrombus. CT proved to be superior for the initial evaluation and subsequent diagnosis of POVT. US was useful for follow-up examinations, and MR imaging results confirmed a case of POVT that was suspected following CT. 相似文献
150.
Increased tumors but uncompromised fertility in the female descendants of mice exposed developmentally to diethylstilbestrol 总被引:11,自引:1,他引:10
Newbold RR; Hanson RB; Jefferson WN; Bullock BC; Haseman J; McLachlan JA 《Carcinogenesis》1998,19(9):1655-1663
Prenatal exposure to diethylstilbestrol (DES) has been associated with the
subsequent development of reproductive tract abnormalities, including poor
reproductive outcome and neoplasia, in experimental animals and humans.
Experimental animal studies with chemical carcinogens have raised the
possibility that adverse effects of DES may be transmitted to succeeding
generations. To evaluate this possibility and to determine if there is a
sensitive window of developmental exposure, outbred CD-1 mice were treated
with DES during three stages of development: group 1 was treated on days
9-16 of gestation (2.5, 5 or 10 microg/kg maternal body wt), the time of
major organogenesis; group II was treated once on day 18 of gestation (1000
microg/kg maternal body wt) just prior to birth; group III was treated on
days 1- 5 of neonatal life (0.002 microg/pup/day). Female mice (F1) in each
group were raised to sexual maturity and bred to control males. As
previously reported, fertility of the F1 DES-exposed females was decreased
in all groups. Female offspring (DES lineage or F2) from these matings were
raised to maturity and housed with control males for 20 weeks. The
fertility of these DES lineage female mice was not affected by DES exposure
of their 'grandmothers'. DES lineage mice were killed at 17-19 and 22-24
months of age. An increased incidence of malignant reproductive tract
tumors, including uterine adenocarcinoma, was seen in DES lineage mice but
not in corresponding controls; the range and prevalence of tumors increased
with age. Because uterine adenocarcinomas were seen in all three DES
groups, all developmental exposure periods were considered susceptible to
the adverse effects of DES. These data suggest that the reduced fertility
observed in the DES F1 female mice was not transmitted to their
descendants; however, increased susceptibility to tumor formation is
apparently transmitted to subsequent generations.
相似文献