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81.
Kashiwakura Y Katoh Y Tamayose K Konishi H Takaya N Yuhara S Yamada M Sugimoto K Daida H 《Circulation》2003,107(16):2078-2081
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Association studies of variants in the genes involved in pancreatic beta-cell function in type 2 diabetes in Japanese subjects 总被引:1,自引:0,他引:1
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Itani T Tachi N Takeyama H Ebara T Takanishi T Murata K Inoue T Suzumura H Kurungkraiong S Khuvasanont T Batino JM 《Industrial health》2006,44(1):17-21
An intervention based on the methodology developed by the International Labour Office, the Work Improvement in Small Enterprises (WISE) was carried out to improve work condition of small-scale enterprises and the informal sector in the Philippines, Thailand and Japan. Through the evaluation of the efficacy of the approaches based on participatory methodology, it is concluded that the method is an efficient measure to improve work condition in small workplaces. It is also pointed out that the activities of supporting experts such as introduction of the methodology and evaluation of the activity are necessary. The important roles of the experts are 1) to encourage managers and workers to sustain the activities for work improvement, 2) to analyse the effectiveness and problems of the implemented improvements, 3) to give appropriate suggestions for the further improvement, and 4) to get materials for demonstrating the effectiveness of WISE activities on improving work conditions and productivity to other managers and workers who have not participated in the activity. 相似文献
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Prevalence of Arrhythmias and Their Risk Factors Mid- and Long-Term After the Arterial Switch Operation 总被引:5,自引:0,他引:5
Hayashi G Kurosaki K Echigo S Kado H Fukushima N Yokota M Niwa K Shinohara T Nakazawa M 《Pediatric cardiology》2006,27(6):689-694
Early results of the arterial switch operation (ASO) for transposition of the great arteries (TGA) are good, but there are
few mid- and long-term data on postoperative arrhythmias, especially in Japan. In this study, clinical data on 624 1-year
survivors who had an ASO between 1976 and 1995 were collected from six institutes in Japan up to October 2002. Sixty (9.6%)
1-year survivors had significant arrhythmias. Bradycardia occurred in 22 patients, including complete atrioventricular block
(CAVB) in 12, sick sinus syndrome (SSS) in 6, and second-degree atrioventricular block in 4. Syncope developed in 2 with CAVB
and 2 with SSS. Ten patients with bradycardia underwent permanent pacemaker implantation. Supraveutricular tachycardia (SVT)
was seen in 25 patients, including paroxysmal supraventricular tachycardia in 16, atrial flutter in 7, and atrial fibrillation
in 2. Six patients with SVT received antiarrhythmic medication. SVT was transient in 20 and persistent in 5. Ventricular arrhythmias
occurred in 13 patients, including nonsustained ventricular tachycardia in 5, paroxysmal ventricular contractions with couplets
in 5, ventricular flutter in 2, and sustained ventricular tachycardia in 1. Four patients with ventricular arrhythmias received
antiarrhythmic medication. Of the study patients, 8 died 1 year or more after ASO. Death was directly related to arrhythmia
in 1 patient and was due to nonsustained ventricular tachycardia with severe congestive heart failure. The presence of a ventricular
septal defect (VSD) was a risk factor for postoperative arrhythmia. Patients with TGA and VSD had more arrhythmias than those
with TGA and an intact ventricular septum (13.7 vs 8.7%, p < 0.05), and this was especially true for CAVB (3.9% vs 1.0%, p < 0.05). In 36 patients clearly documented time onset of postoperative arrhythmia arrhythmia developed in 18 (50%) after
less than 1 year and in 15 (42%) after more than 5 years. In summary serious arrhythmias after ASO were uncommon, but postoperative
arrhythmias, such as unpaced CAVB, SSS, and VT, were related to morbidity and mortality. VSD was a risk factor for postoperative
arrhythmia, especially CAVB. Approximately half of the arrhythmias developed late. Lifelong monitoring with respect to arrhythmia
is needed for patients after ASO. 相似文献
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Purpose Several methods of revascularization after mesenteric ischemia have been proposed. Using a new route, we performed retrograde loop bypass grafting to the superior mesenteric artery (SMA) with a ringed expanded polytetrafluoroethylene (ePTFE) graft.Methods We anastomosed the graft to the infrarenal aorta, which ran behind the left renal hilum, turned ventral, and was anastomosed to the SMA in an antegrade fashion hemodynamically. Five patients underwent this procedure, which resulted in remarkable symptomatic relief.Results There were no postoperative deaths or serious complications, although some patients suffered paralytic ileus. All of the grafts remained patent during long-term follow-up, ranging from 17 to 72 months (mean: 37.8 months). Postoperative angiograms showed good configuration of the graft, which did not compress the renal vessels.Conclusion Infrarenal aorta-SMA bypass relieved mesenteric ischemia and achieved good long-term graft patency. Thus, we consider it to be an effective and durable vascular procedure to reduce postoperative mortality and morbidity. 相似文献
90.
Surgical strategy for treating renal cell carcinoma with thrombus extending into the inferior vena cava 总被引:4,自引:0,他引:4
Jibiki M Iwai T Inoue Y Sugano N Kihara K Hyochi N Sunamori M 《Journal of vascular surgery》2004,39(4):829-835
OBJECTIVE: A surgical strategy for treating malignant renal tumors with thrombus extending into the inferior vena cava (IVC) was assessed. METHODS: We retrospectively reviewed the records for all patients with renal cell carcinoma (RCC; n=30) or Wilms tumor (n=1) with tumor thrombus extending into the IVC who underwent surgical intervention at our institution between January 1980 and December 2001. Tumors were classified preoperatively according to the cephalad extension of thrombus, and intraoperative procedures were selected on the basis of degree of extension. Patients with RCC underwent radical nephrectomy and removal of thrombus with (n=11) or without (n=19) IVC resection. Partial normothermic cardiopulmonary bypass without cardiac arrest was used in 4 patients. The Pringle maneuver was performed in 8 patients. Infrarenal abdominal aortic cross-clamping was used in 8 patients to maintain systemic blood pressure. IVC cross-clamping and the Pringle maneuver were performed in 5 patients with suprahepatic thrombus extension. Temporary placement of a filter in the IVC or plication of the IVC above the hepatic vein was performed before hepatic mobilization, to decrease the risk for pulmonary embolism. RESULTS: One patient died intraoperatively of pulmonary embolism. Postoperative complications occurred in 11 patients; all resolved with conservative therapy. The postoperative duration of survival in patients with RCC was 37 +/- 44 months (range, 4-180 months); the 5-year survival rate was 42%. CONCLUSION: Aortic cross-clamping during IVC occlusion prevented hypotension and maintained hemodynamic stability that has required bypass in other series. This surgical treatment with the less extensive approach could result in long-term survival of patients with RCC in whom tumor thrombus extends into the IVC. We recommend that radical nephrectomy and tumor thrombectomy, with or without caval resection, be performed in these patients, with less invasive additional maneuvers. 相似文献