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81.
Javid Safa Mohammad Reza Ardalan Mohammadamin Rezazadehsaatlou Mehran Mesgari Reza Mahdavi Maryam Poorkar Jadid 《International urology and nephrology》2014,46(8):1633-1638
Background
Chronic renal failure is a progressive and irreversible loss of kidney function, and the hemodialysis (HD) is one of the most common modalities in this regard. Oxidative stresses [like interleukin-8 (IL-8) and tumor necrosis factor-alpha (TNF-α)] and inflammation are the main risk factors associated with cardiovascular diseases and other complications in many organs in hemodialysis patients; meanwhile, antioxidants like alpha lipoic acid (ALA) may reduce the oxidative stress markers and the levels of inflammatory cytokines, so can improve of the patient’s quality of life.Methods
In this randomized clinical trial study, 60 HD patients were randomly categorized in two case and control groups. Case group received a daily capsule of 600 mg of ALA supplementation for 8 weeks, and the control group received placebo capsules daily. The serum level of IL-8 and TNF-α was measured in both groups before and after the intervention.Results
There were no significant differences in age, gender, duration of dialysis, and causative factor for dialysis between both groups (P > 0.05). The mean of IL-8 and TNF-α after the intervention in case group was 26.20 ± 15.34 and 21.25 ± 9.61, respectively; the difference between both groups was not statistically significant (P > 0.05).Conclusion
Based on the better feeling and other beneficial effects of ALA were found in our study; we can conclude that it is a beneficial and recommended supplement, especially, for diabetic and dialysis patients. 相似文献82.
Amanda Roberts MD MPH Mehran Habibi MD Kevin D. Frick PhD 《Annals of surgical oncology》2014,21(7):2209-2217
Background
A growing number of women with sporadic unilateral, early-stage breast cancers are undergoing ipsilateral therapeutic mastectomy with contralateral prophylactic mastectomy (CPM) to prevent the development of new cancers in the contralateral breast.Methods
A decision-tree using TreeAge Pro 2012 software was used to model the costs and effects of CPM versus unilateral mastectomy (UM) in women younger than 50 years of age with sporadic unilateral, early stage breast cancers. Cost estimates were obtained from the Medicare Fee Schedule and the Healthcare Utilization Project. Probability estimates were obtained from the literature. Outcome effects were measured by incremental cost per quality-adjusted life year (QALY) gained. A 10-year risk period for contralateral breast cancer (CBC), a lifetime time horizon, and a societal perspective were used.Results
Treatment with CPM results in 0.2 QALYs less than UM and $279 less in costs during a 10-year risk period and lifetime follow-up. The resulting incremental cost effectiveness ratio (ICER) is a savings of $1397 per QALY lost. The ICER is sensitive to the rate and method of postmastectomy reconstruction and the cost of radiologic surveillance after UM.Conclusions
CPM is cost-saving for the prevention of CBC in women younger than 50 years of age with sporadic, unilateral, early-stage breast cancers, but also reduces resulting health. The savings for health lost are insufficient to be considered cost-effective at this time. 相似文献83.
Fracture characteristics were used to effectively evaluate the performance of fiber-reinforced cementitious composites. The fracture parameters provided the basis for crack stability analysis, service performance, safety evaluation, and protection. Much research has been carried out in the proposed study field over the previous two decades. Therefore, it was required to analyze the research trend from the available bibliometric data. In this study, the scientometric analysis and science mapping techniques were performed along with a comprehensive discussion to identify the relevant publication field, highly used keywords, most active authors, most cited articles, and regions with largest impact on the field of fracture properties of cement-based materials (CBMs). Furthermore, the characteristic of various fibers such as steel, polymeric, inorganic, and carbon fibers are discussed, and the factors affecting the fracture properties of fiber-reinforced CBMs (FRCBMs) are reviewed. In addition, future gaps are identified. The graphical representation based on the scientometric review could be helpful for research scholars from different countries in developing research cooperation, creating joint ventures, and exchanging innovative technologies and ideas. 相似文献
84.
Anastasios Roumeliotis MD Bimmer E. Claessen MD PhD Samantha Sartori PhD Davide Cao MD Hanbo Qiu Anton Camaj MD MS Johny Nicolas MD Rishi Chandiramani MD Ridhima Goel MD Mauro Chiarito MD Rebecca Torguson MPH Joseph Sweeny MD Nitin Barman MD Prakash Krishnan MD Annapoorna Kini MD Samin K Sharma MD George Dangas MD PhD Roxana Mehran MD 《Catheterization and cardiovascular interventions》2021,98(4):E494-E500
85.
Alexandre Abizaid MD PhD Carlos M. Campos MD PhD Patrícia O. Guimarães MD PhD José de Ribamar Costa Jr. PhD MD Breno A. A. Falcão MD PhD Fernanda Mangione MD Adriano Caixeta MD PhD Pedro A. Lemos MD PhD Fabio S. de Brito Jr. MD PhD Ricardo Cavalcante MD Cristiano Guedes Bezerra MD PhD Leandro Cortes MD Henrique B. Ribeiro MD PhD Francis R. de Souza PhD Natassja Huemer BS Renata M. do Val BS Bruno Caramelli MD PhD Daniela Calderaro MD PhD Felipe G. Lima MD Ludhmila A. Hajjar MD PhD Roxana Mehran MD Roberto Kalil Filho MD PhD the COVID MI investigators 《Catheterization and cardiovascular interventions》2021,98(3):E370-E378
86.
87.
Keisuke Yasumura MD Benjamin Benhuri MD Yuliya Vengrenyuk PhD Artiom Petrov MD Nitin Barman MD Joseph Sweeny MD Vishal Kapur MD Javed Suleman MD Usman Baber MD Roxana Mehran MD Gregg W. Stone MD Annapoorna S. Kini MD Samin K. Sharma MD 《Catheterization and cardiovascular interventions》2021,97(3):E280-E287
88.
Akbar Dorgalaleh Emmanuel J. Favaloro Mehran Bahraini Fariba Rad 《International journal of laboratory hematology》2021,43(1):21-28
The prothrombin time (PT) represents the most commonly used coagulation test in clinical laboratories. The PT is mathematically converted to the international normalized ratio (INR) for use in monitoring anticoagulant therapy with vitamin K antagonists such as warfarin in order to provide test results that are adjusted for thromboplastin and instrument used. The INR is created using two major PT ‘correction factors’, namely the mean normal PT (MNPT) and the international sensitivity index (ISI). Manufacturers of reagents and coagulometers have made some efforts to harmonizing INRs, for example, by tailoring reagents to specific coagulometers and provide associated ISI values. Thus, two types of ISIs may be generated, with one being a ‘general’ or ‘generic’ ISI and others being reagent/coagulometer-specific ISI values. Although these play a crucial role in improving INR results between laboratories, these laboratories reported INR values are known to still differ, even when laboratories use the same thromboplastin reagent and coagulometer. Moreover, ISI values for a specific thromboplastin can vary among different models of coagulometers from a manufacturer using the same method for clot identification. All these factors can be sources of error for INR reporting, which in turn can significantly affect patient management. In this narrative review, we provide some guidance to appropriate ISI verification/validation, which may help decrease the variability in cross laboratory reporting of INRs. 相似文献
89.
90.