全文获取类型
收费全文 | 209452篇 |
免费 | 3171篇 |
国内免费 | 160篇 |
专业分类
耳鼻咽喉 | 1618篇 |
儿科学 | 7429篇 |
妇产科学 | 3625篇 |
基础医学 | 20675篇 |
口腔科学 | 2201篇 |
临床医学 | 15652篇 |
内科学 | 38920篇 |
皮肤病学 | 1062篇 |
神经病学 | 19629篇 |
特种医学 | 10239篇 |
外国民族医学 | 1篇 |
外科学 | 34868篇 |
综合类 | 2540篇 |
一般理论 | 18篇 |
预防医学 | 20105篇 |
眼科学 | 3177篇 |
药学 | 11386篇 |
中国医学 | 668篇 |
肿瘤学 | 18970篇 |
出版年
2023年 | 210篇 |
2022年 | 400篇 |
2021年 | 902篇 |
2020年 | 551篇 |
2019年 | 905篇 |
2018年 | 22881篇 |
2017年 | 18018篇 |
2016年 | 20146篇 |
2015年 | 1793篇 |
2014年 | 2125篇 |
2013年 | 2586篇 |
2012年 | 9547篇 |
2011年 | 23680篇 |
2010年 | 20327篇 |
2009年 | 12960篇 |
2008年 | 21783篇 |
2007年 | 24097篇 |
2006年 | 2926篇 |
2005年 | 4450篇 |
2004年 | 5433篇 |
2003年 | 6259篇 |
2002年 | 4222篇 |
2001年 | 557篇 |
2000年 | 587篇 |
1999年 | 419篇 |
1998年 | 590篇 |
1997年 | 516篇 |
1996年 | 316篇 |
1995年 | 335篇 |
1994年 | 290篇 |
1993年 | 245篇 |
1992年 | 164篇 |
1991年 | 222篇 |
1990年 | 242篇 |
1989年 | 176篇 |
1988年 | 141篇 |
1987年 | 108篇 |
1986年 | 100篇 |
1985年 | 109篇 |
1984年 | 119篇 |
1983年 | 124篇 |
1982年 | 121篇 |
1981年 | 89篇 |
1980年 | 110篇 |
1979年 | 54篇 |
1978年 | 56篇 |
1974年 | 56篇 |
1938年 | 60篇 |
1932年 | 57篇 |
1930年 | 47篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
101.
Marlene S. See M. R. Foxton N. A. Miedzianowski-Sinclair C. E. Roberts C. Nduka 《European journal of plastic surgery》2007,29(8):387-393
The nasolabial fold is a significant facial landmark. Its size, shape, and symmetry are important in facial reanimation surgery,
while effacement is an important goal in rejuvenation surgery. However, quantitative data for the nasolabial fold volume (NLFV)
and depth is still unavailable. We present a new method of measurement using 3D color speckle stereophotogrammetry and its
application in the assessment of NLFV. The VECTRA-3D system was validated to determine its minimum resolution and accuracy.
Normal volunteers aged 13–84 years (n = 87) were imaged in repose. Mother–daughter pairs (n = 15, aged 13–61) were imaged in the upright and supine positions. All data were processed using custom software and analyzed
by linear regression and nonparametric tests as appropriate. NLFV varied from 0.0026 to 0.2306 ml. There was significant correlation
between NLFV and age (r = 0.7269, p < 0.0001). Men had significantly higher NLFV than women across all ages. There was no significant difference between the
left and right NLFV. NLFV altered significantly from upright to supine in all subjects (p = 0.0012). However, the mothers increased their NLFV by 32% from supine to upright postures, which was a greater change than
observed in their daughters. We have demonstrated a rapid, objective, and non-invasive assessment tool for facial reanimation
and rejuvenation surgery. We have quantified the effects of age and posture on NLFV, and the efficacy and longevity of rejuvenation
procedures are currently under investigation. 相似文献
102.
103.
104.
Jamshid Shirani Jagat Narula William C. Eckelman Navneet Narula Vasken Dilsizian 《Journal of nuclear cardiology》2007,14(1):100-110
Conclusions Noninvasive imaging of neurohumoral upregulation in remodeled myocardium suggests that an imaging strategy can be developed
for predicting the rate of remodeling and likelihood of HF development. This should allow a more judicious use of neurohumoral
antagonists especially in subjects who do not have manifest HF.74 In others specific targeted imaging may allow timely selection of individualized treatment strategies and ensure optimization
of therapeutic intervention. Similar to ACE and AII receptors, multiple other targets in the hormonal cascades can identify
the likelihood of adverse and favorable remodeling.74 相似文献
105.
Yuji Takeda Naoki Minato Yuji Katayama Tomoki Shimokawa 《General thoracic and cardiovascular surgery》2005,53(1):42-45
Two successful cases of the surgical treatment for coronary artery aneurysm (non-Kawasaki disease) were reported. The first
case had a saccular aneurysm on the left circumflex coronary artery (LCx) #14. Resection of the LCx aneurysm was performed
subsequent to single vessel coronary artery bypass grafting (CABG) to the distal portion of LCx#14 under the cardioplegic
cardiac arrest. The second case had aneurysms on both the left anterior descending artery (LAD) #7 (fusiform) and the LCx#11
(saccular). After double vessel CABG to LAD#7 and LCx#11, ligation or resection of two aneurysms was performed successfully.
Postoperative courses have been uneventful with good angiographic results achieved. Since these surgical procedures demonstrated
safety, the patients are expected to achieve a good long-term prognosis. 相似文献
106.
Kimihiro Shimizu Yoshimi Otani Takashi Ibe Osamu Kawashima Mituhiro Kamiyoshihara Yasuo Morishita 《General thoracic and cardiovascular surgery》2005,53(1):39-41
Late-onset chylothorax occurred 49 days after right lower lobectomy for lung cancer in a 76-year-old man. Chylothorax was successfully managed by conservative treatment with chest tube drainage and an enteral low-fat diet. Chylothorax may occur in the late period after pulmonary resection and systematic mediastinal lymph node dissection for lung cancer, for which conservative management is the treatment of choice. 相似文献
107.
108.
Scarlett Lin Gomez Cynthia D O'Malley Antoinette Stroup Sarah J Shema William A Satariano 《BMC cancer》2007,7(1):193
Background
Colorectal cancer, if detected early, has greater than 90% 5-year survival. However, survival has been shown to vary across racial/ethnic groups in the United States, despite the availability of early detection methods. 相似文献109.
Carmen Guillén Ponce María Pilar Garrido López María José Molina Garrido Gema Muñoz Molina Alfredo Carrato 《Clinical & translational oncology》2007,9(1):53-55
Pituitary metastases of solid tumours are infrequent, specially as a first manifestation. When they happen, they are usually
due to breast or lung cancer and are asymptomatic or produce diabetes insipidus. It is very strange that they produce hormonal
deficiency.
We present a case report of a bronchogenic adenocarcinoma in a 65-year-old man which began with panhypopituitarism, diabetes
insipidus and visual alterations. Magnetic resonance imaging revealed a large sellar mass, with clivus infiltration and invading
the right cavernous sinus. The biopsy result was adenocarcinoma metastases from lung cancer. 相似文献
110.
Philip S Wells Josdalyne L Anderson Marc A Rodger Nancy Carson Rebecca L Grimwood Steve P Doucette 《Blood coagulation & fibrinolysis》2006,17(7):533-538
The substitution of leucine for valine at amino acid position 34 of the factor XIII gene is commonly referred to as FXIII Val34Leu polymorphism. The homozygous leucine/leucine genotype has been reported to confer protection against venous thromboembolism, but previous studies have not evaluated a population limited to those with idiopathic venous thromboembolism. The primary objective of the study was to determine whether the FXIII Val34Leu polymorphism is independently associated with the occurrence of idiopathic venous thromboembolism. We prospectively enrolled consecutive patients with at least one objectively confirmed idiopathic venous thromboembolism. Friends of cases were recruited as controls and matched to cases by sex, ethnicity, and age. All participants were tested for the FXIII Val34Leu polymorphism in addition to several well-known thrombophilias. Data from 309 cases and 306 controls were analyzed. The FXIII leucine/leucine genotype was present in 4.9% of cases and 6.5% of controls. An adjusted odds ratio of 0.59 (95% confidence interval, 0.25-1.38) was found for the recessive model and 0.69 (95% confidence interval, 0.46-1.02) for the dominant model. Our results do not support an independent association of the FXIII Val34Leu polymorphism with idiopathic venous thromboembolism in our Caucasian Canadian study population. 相似文献