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81.
Angelo Andriulli Vito Di Marco Maurizio Margaglione Antonio Massimo Ippolito Giovanna Fattovich Antonina Smedile Maria Rosa Valvano Vincenza Calvaruso Domenica Gioffreda Michele Milella Filomena Morisco Martina Felder Giuseppina Brancaccio Massimo Fasano Pietro Gatti Paolo Tundo Michele Barone Raffaele Cozzolongo Mario Angelico Giovanna D’Andrea Nicola Andriulli Maria Lorena Abate Giuseppe Mazzella Giovanni Battista Gaeta Antonio Craxi Teresa Santantonio 《Journal of hepatology》2014
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Valerio Gallotta Anna Fagotti Francesco Fanfani Gabriella Ferrandina Camilla Nero Barbara Costantini Salvatore Gueli Alletti Vito Chiantera Alfredo Ercoli Giovanni Scambia 《Surgical endoscopy》2014,28(6):1808-1815
Background
Optimally, secondary cytoreduction is acknowledged as a valid option in terms of oncologic outcome for patients with platinum-sensitive recurrent ovarian cancer. In cases of localized relapse, a laparoscopic approach has been attempted at various institutions, but studies on its role for this subset of patients still are limited. This report describes the authors’ experience using laparoscopic secondary cytoreduction for patients with localized recurrent ovarian cancer. The results from a retrospective analysis of a prospective case series are reported.Methods
Between October 2011 and May 2013, 29 patients with localized recurrent ovarian cancer were selected for a laparoscopic cytoreduction. Two conversions to laparotomy occurred. The analyzed outcome variables included stage and site of disease, type of surgical procedure, operative time, blood loss, length of hospital stay, complications, and oncologic outcome.Results
The median operating time was 188 min. The median estimated blood loss was 150 mL, and the median hospital stay was 4 days. Complete debulking was achieved for 96.2 % of the patients. No intraoperative complications occurred, and postoperative complications were noted in only one patient. The median disease-free survival time was 14 months.Conclusions
For selected patients, laparoscopy is a feasible and safe approach to optimal cytoreduction for patients with localized recurrent ovarian cancer. 相似文献85.
Lorenzo Brognara Iacopo Volta Vito Michele Cassano Emmanuel Navarro-Flores Omar Cauli 《Pathophysiology》2020,27(1):14
Diabetes mellitus is associated with impairment in cognitive functions which can complicate adherence to self-care behaviors. We evaluated the incidence of cognitive impairment in patients with diabetes mellitus to determine the strength of the association between diabetic foot (a complication that occurs in about 10% of diabetic patients), adherence to the clinician’s recommendations, glycemic control, and cognitive function. A prospective study was carried out in a probabilistic sample of older patients with diabetic foot living in three nursing homes. Cognitive functions were evaluated by the MMSE (Mini-Mental State Examination), the Trail Making test (TMT), and the Michigan neuropathy screening instrument (MNSI). There were no significant associations between cognitive function and neuropathy or foot alterations, although glycated hemoglobin (HB1Ac > 7%) significantly (p < 0.05) associated with MMSE and adherence to treatment in the 1 month follow-up visit. Receiver operating characteristic curve analysis showed that both HB1Ac and the MNSI score significantly (p < 0.05) discriminate subsequent adherence to treatment for foot complication, with a sensitivity of 80.0–73.3% and specificity 70.6–64.7%, respectively. Proper control of foot complications in diabetic patients involves appropriate glycemic control and less severe neuropathy, and seems to be unrelated to cognitive dysfunction, and warrants further studies in order to tailor appropriate treatments to central and peripheral nervous system disorders. Poor glycemic control (Hb1Ac level > 7%) and a neuropathy score of 5.5 in the MNSI are the best-cut off points to discriminate poor adherence to the clinician’s recommendations for self-care behaviors in people with diabetic foot complication. In this study, we observed that foot disorders were associated with impaired global cognitive function in elderly patients (aged ≥ 65). Podiatrists and physicians should consider cognitive dysfunction as an important chronic complication in the management of diabetic foot. 相似文献
86.
Jakub Trizuljak Wolfgang R. Sperr Lucie Nekvindová Hanneke O. Elberink Karoline V. Gleixner Aleksandra Gorska Magdalena Lange Karin Hartmann Anja Illerhaus Massimiliano Bonifacio Cecelia Perkins Chiara Elena Luca Malcovati Anna B. Fortina Khalid Shoumariyeh Mohamad Jawhar Roberta Zanotti Patrizia Bonadonna Francesca Caroppo Alexander Zink Massimo Triggiani Roberta Parente Nikolas von Bubnoff Akif S. Yavuz Hans Hägglund Mattias Mattsson Jens Panse Nadja Jäkel Alex Kilbertus Olivier Hermine Michel Arock David Fuchs Vito Sabato Knut Brockow Agnes Bretterklieber Marek Niedoszytko Björn van Anrooij Andreas Reiter Jason Gotlib Hanneke C. Kluin-Nelemans Jiri Mayer Michael Doubek Peter Valent 《Allergy》2020,75(8):1927-1938
87.
COVID-19 survival associates with the immunoglobulin response to the SARS-CoV-2 spike receptor binding domain 总被引:1,自引:0,他引:1
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A good supporting material for Ziegler-Natta type catalysts was obtained by reaction between powdered metallic magnesium and 1-chloro-n-CmH2m+1 (m = 3–9). This reaction affords a highly disordered form of MgCl2 which was characterized by FT-IR spectroscopy and powder X-ray diffraction (XRD) analysis. This MgCl2 form shows a crystallographic disorder much higher than that exhibited by the products obtained following the commercial activation procedures of α-MgCl2, either mechanical or chemical. As shown by the XRD spectra, the synthetized MgCl2 is characterized by the typical structure of the δ-form. Therefore, this MgCl2 form, in view of its highly disordered structure, appears as a promising material for the preparation of active supported Ziegler-Natta type catalysts. Thus, by titanation of the obtained δ-MgCl2 we have prepared some supported catalysts which have been tested in the slurry propene polymerizations, showing high activity (136000–138000 gPP/gTi) and good stereoselectivity (82–88% I.I.). 相似文献
90.
Gastaldi Matteo Scaranzin Silvia Jarius Sven Wildeman Brigitte Zardini Elisabetta Mallucci Giulia Rigoni Eleonora Vegezzi Elisa Foiadelli Thomas Savasta Salvatore Banfi Paola Versino Maurizio Benedetti Luana Novi Giovanni Mancardi Margherita Maria Giacomini Thea Annovazzi Pietro Baroncini Damiano Ferraro Diana Lampasona Vito Reindl Markus Waters Patrick Franciotta Diego 《Journal of neurology》2020,267(12):3555-3564
Journal of Neurology - The detection of antibodies to myelin oligodendrocyte glycoprotein (MOG) is fundamental for the identification of MOG antibody-associated disorders (MOGAD), and the... 相似文献