全文获取类型
收费全文 | 8844篇 |
免费 | 446篇 |
国内免费 | 22篇 |
专业分类
耳鼻咽喉 | 110篇 |
儿科学 | 777篇 |
妇产科学 | 367篇 |
基础医学 | 919篇 |
口腔科学 | 161篇 |
临床医学 | 430篇 |
内科学 | 1621篇 |
皮肤病学 | 152篇 |
神经病学 | 332篇 |
特种医学 | 201篇 |
外科学 | 1773篇 |
综合类 | 265篇 |
一般理论 | 2篇 |
预防医学 | 350篇 |
眼科学 | 579篇 |
药学 | 479篇 |
中国医学 | 24篇 |
肿瘤学 | 770篇 |
出版年
2023年 | 68篇 |
2022年 | 157篇 |
2021年 | 287篇 |
2020年 | 142篇 |
2019年 | 199篇 |
2018年 | 284篇 |
2017年 | 192篇 |
2016年 | 252篇 |
2015年 | 220篇 |
2014年 | 327篇 |
2013年 | 380篇 |
2012年 | 563篇 |
2011年 | 569篇 |
2010年 | 357篇 |
2009年 | 279篇 |
2008年 | 455篇 |
2007年 | 487篇 |
2006年 | 451篇 |
2005年 | 368篇 |
2004年 | 309篇 |
2003年 | 288篇 |
2002年 | 251篇 |
2001年 | 221篇 |
2000年 | 218篇 |
1999年 | 194篇 |
1998年 | 89篇 |
1997年 | 56篇 |
1996年 | 46篇 |
1995年 | 41篇 |
1992年 | 95篇 |
1991年 | 95篇 |
1990年 | 74篇 |
1989年 | 73篇 |
1988年 | 71篇 |
1987年 | 77篇 |
1986年 | 83篇 |
1985年 | 106篇 |
1984年 | 56篇 |
1983年 | 57篇 |
1982年 | 39篇 |
1981年 | 35篇 |
1980年 | 34篇 |
1979年 | 80篇 |
1978年 | 45篇 |
1977年 | 47篇 |
1976年 | 39篇 |
1975年 | 35篇 |
1974年 | 42篇 |
1973年 | 48篇 |
1972年 | 46篇 |
排序方式: 共有9312条查询结果,搜索用时 0 毫秒
81.
Lalita Chaudhari O P Tandon N Vaney N Agarwal 《Indian journal of physiology and pharmacology》2003,47(1):75-80
Electrophysiological correlates of sensory function in diabetic pregnancy have not been documented. Present study reports changes in Auditory evoked responses (AER) in gestational diabetics when compared with normal pregnant controls. Human AER are generally classified into early Auditory brainstem responses (AER), Mid latency responses (MLR) and late Slow vertex responses (SVR). These potentials were recorded in 20 women with diabetic pregnancy using Ag/AgCl electrodes from Cz-A1 and Cz-A2 position on MEB 5200 Neuropack II ... plus (Nihon Kohden, Japan) Evoked Potential Recorder. The evoked potentials in gestational diabetics were compared with 20 age matched normal pregnant women using Student's t-test. Absolute latencies of waves I to V, Inter peak latencies I-III and I-V of ABR were significantly increased whereas amplitude of wave V decreased in diabetic pregnant women. No significant change in latency of any component of MLR was observed between the two groups whereas significant prolongation of latencies of all components of SVR was observed in diabetic pregnant women as compared to normal control group. These findings indicate prolongation of both peripheral transmission time (PTT) and central transmission time (CTT) in diabetic pregnant females. Prolongation of latencies of SVR components in this study implicates cortex in the central diabetic neuropathy in women with gestational diabetes. 相似文献
82.
Cai Grau Jai Prakash Agarwal Kaukab Jabeen Abdul Rab Khan Sarath Abeyakoon Tatiana Hadjieva Ibrahim Wahid Sedat Turkan Hideo Tatsuzaki Ketayun A Dinshaw Jens Overgaard 《Radiotherapy and oncology》2003,67(1):17-26
BACKGROUND AND PURPOSE: Single agent mitomycin c (MMC) has been shown to improve the outcome of radiotherapy in single institution trials. In order to confirm these findings in a broader worldwide setting, the International Atomic Energy Agency (IAEA) initiated a multicentre trial randomising between radiotherapy alone versus radiotherapy plus MMC. MATERIAL AND METHODS: Patients with advanced head and neck cancer were treated with primary curative radiotherapy (66 Gy in 33 fractions with five fractions per week) +/-a single injection (15 mg/m(2)) of MMC at the end of the first week of radiotherapy. Stratification parameters were tumour localization, T-stage, N-stage, and institution. A total of 558 patients were recruited in the trial from February 1996 to December 1999. Insufficient accrual and reporting led to the exclusion of three centres. The final study population consisted of 478 patients from seven centres. Patients had stage III (n=223) or stage IV (n=255) squamous cell carcinoma of the oral cavity (n=230), oropharynx (n=140), hypopharynx (n=65) or larynx (n=43). Prognostic factors like age, gender, site, size, differentiation and stage were well balanced between the two arms. RESULTS: The haematological side effects of MMC were very modest (<5% grade 3-4) and did not require any specific interventions. Furthermore, MMC did not enhance the incidence or severity of acute and late radiation side effects. Confluent mucositis and dry skin desquamation was common, occurring in 56% and 62% of patients, respectively. The overall 3-year primary locoregional tumour control, disease-specific and overall survival rates were 19, 36 and 30%, respectively. Gender, haemoglobin drop, tumour site, tumour and nodal stage were significant parameters for loco-regional tumour control. There was no significant effect of MMC on locoregional control or survival, except for the 161 N0 patients, where MMC resulted in a better loco-regional control (3-year estimate 16% vs. 29%, P=0.01). CONCLUSIONS: The study did not show any major influence of MMC on loco-regional tumour control, survival or morbidity after primary radiotherapy in stage III-IV head and neck cancer except in N0 patients where loco-regional control was significantly improved. 相似文献
83.
Vedang Murthy Jai Prakash Agarwal Rakesh Jalali Roshni F Chinoy 《Journal of Medical Imaging and Radiation Oncology》2003,47(2):202-204
Solitary extramedullary plasmacytoma is a rare tumour with radiotherapy playing an important role in its management. This report describes the case history of a man with a solitary extramedullary plasmacytoma at an extremely rare site, the premaxilla, that posed certain diagnostic and therapeutic dilemmas. The patient underwent surgery followed by postoperative radiotherapy. The use of two modalities of treatment for this localized tumour has been justified by briefly reviewing the literature and defining the various prognostic factors. These prognostic factors in turn should guide the treatment of these uncommon tumours. 相似文献
84.
85.
R. S. Sidhu R. K. Sharma S. Kachoria C. Curtis A. Agarwal 《Journal of assisted reproduction and genetics》1997,14(6):354-360
Purpose: Recruiting donors to a sperm bank program is difficult and slow because of high dropout rates and high rejection rates. The
profile of successful and unsuccessful donors was determined at our sperm bank.
Methods: A total of 199 men was screened from 1986 to 1994 in the anonymous sperm bank donor program; 174 (87%) men dropped out or
did not meet minimum guidelines. The study included 25 accepted donors and 20 rejected men (of 52 rejected donors, only 20
donors who came for two consecutive semen analyses were selected). Sperm quality variables and demographic data were compared
between the groups.
Results: Accepted donors had significantly better semen quality in motility, velocity, linearity, and ALH than did rejected donors
(P < 0.01). More rejected donors than accepted donors were single (P < 0.01). A higher percentage of accepted donors consumed caffeine (P < 0.001), and they were more likely to have college degrees (P < 0.03).
Conclusions: These results indicate that loss of interest and poor semen quality were the major reasons for rejection of donors in our
anonymous donor sperm bank program. 相似文献
86.
Agarwal P 《Journal of the Indian Medical Association》2000,98(5):216, 223
87.
Kathirvel S Prakash A Lokesh BN Sujatha P 《Anesthesia and analgesia》2000,91(4):1029-31, table of contents
Implications: This case report describes the anesthetic considerations for a patient with paroxysmal nocturnal hemoglobinuria. Specific strategies to be applied in the perioperative period to prevent hemolytic episodes and venous thrombosis are also discussed. 相似文献
88.
Mario Sanna Abdelkader Taibah Alessandra Russo Maurizio Falcioni Manoj Agarwal 《Otology & neurotology》2004,25(3):379-386
OBJECTIVE: Retrospective study and review of the complications other than those related to the facial nerve and hearing, encountered in acoustic neuroma surgery. Also, an evaluation of hospital stay and its relation with various factors. STUDY DESIGN: Retrospective case review. SETTING: Tertiary neurotologic and skull base referral center. PATIENTS: A series of 707 patients who underwent surgical removal of acoustic neuroma from April 1987 to December 2001. INTERVENTIONS: The surgical approaches used were the enlarged translabyrinthine approach, the enlarged middle fossa approach, and the retrosigmoid approach. In a small number of cases, the operations were performed through other approaches. MAIN OUTCOME MEASURES: The duration of hospital stay and appearance of complications in the perioperative period along with their management. Results related to the facial nerve and hearing were not considered in this study. RESULTS: The most frequent complication was abdominal subcutaneous hematoma (site of fat harvest), which occurred in 23 patients (3.2%). Cerebrospinal fluid leak was present in 20 patients (2.8%), 15 of whom needed revision surgery. Other complications included VIth cranial nerve dysfunction in 12 cases (1.68%), subdural hematoma in 3 cases (0.4%), cerebellopontine angle hematoma in 4 cases (0.6%), cerebellar edema in 2 cases (0.28%), brainstem hematoma in 1 case (0.14%), transitory aphasia in 1 case (0.14%), and lower cranial nerve dysfunction in 1 case (0.14%). Mortality occurred in only one case (0.14%). Medical complications seldom occurred. The postoperative hospital stay ranged from 2 to 36 days, with an average of 6.4 days. The overall hospital stay diminished over time from 10.2 days in 1987 to 1990, to 4.9 days in 2001. There was a significant relation between hospital stay and tumor size, approach used, and presence/absence of complications. CONCLUSIONS: Perioperative complications in acoustic neuroma surgery do exist, but this study demonstrated how low the incidence is. The authors believe that the low percentage of complications is mainly attributable to the majority of operations being carried out in specialized clinics, where they are considered routine operations. They believe that following individualized approaches, depending on tumor size and on the preoperative function of the cranial nerves, is the proper way to reach a significant reduction in complications while maintaining a high percentage of total tumor removal. The results of this study, considered as a basis of comparison with other studies, will certainly be useful in preoperative patient counseling. 相似文献
89.
Mario Sanna Paolo Piazza Giuseppe Ditrapani Manoj Agarwal 《Otology & neurotology》2004,25(6):998-1005
OBJECTIVE: To present our experience with permanent preoperative balloon occlusion of the internal carotid artery while dealing with different abnormalities of the lateral skull base and a comparison with the results mentioned in the literature. STUDY DESIGN: Retrospective case review. SETTING: Private neurotologic and skull base tertiary referral center. PATIENTS: Fifteen patients who underwent preoperative balloon occlusion of the internal carotid artery and surgery subsequently for various abnormalities of the lateral skull base between 1989 and 2002. INTERVENTIONS: Each patient was subjected to four-vessel angiography along with the manual cross-compression test and balloon test occlusion to assess the efficacy of the collateral circulation. After angiography, each patient underwent a preoperative balloon occlusion, after which a lateral skull base procedure was performed for removal of the abnormality. MAIN OUTCOME MEASURES: Only those patients showing evidence of adequate collateral cerebral circulation and a less than 1-second delay between the angiographic phases of the two cerebral hemispheres on angiography were considered fit for preoperative balloon occlusion. While under going the preoperative balloon occlusion, the patients were clinically assessed for the development of any neurologic symptoms and signs. Long-term follow-up after surgery was also based on the development of symptoms and signs of neurovascular compromise. RESULTS: A major complication in the form of long-lasting hemiplegia occurred in one patient (6.7%). This complication was the result of technical factors rather than an effect of cerebral ischemia, because it was caused by an intimal dissection produced by the catheter. A defect in the visual field occurred in one patient (6.7%) that resolved partially after antiplatelet therapy. There was no mortality in our series related to preoperative balloon occlusion of the internal carotid artery. CONCLUSION: Preoperative balloon occlusion of the internal carotid artery can still be considered a viable option for the management of the internal carotid artery during lateral skull base surgery. Proper preoperative evaluation of the adequacy and efficacy of the collateral cerebral circulation reduces the chances of postoperative neurovascular complications. 相似文献
90.
Akash Belenje Brijesh Takkar Komal Agarwal Mudit Tyagi Vinod Aggarwal Tapas R Padhi Raja Narayanan 《Indian journal of ophthalmology》2022,70(3):902
Purpose:To evaluate the causes of jet stream injury (JSI)-related iatrogenic retinal breaks (IRBs) during vitreoretinal surgery (VRS).Methods:The precise surgical environment, which includes the indication and type of surgical procedure, retina status, details of instrumentation and fluidic parameters, and characteristics of the jet responsible for the IRB, was noted from case records. The nature of IRB and its healing and impact on anatomical and visual outcomes were analyzed.Results:Five eyes of five patients with complete documentation of both the JSI and the IRB were included. Two cases were operated for macular hole, and one each for vitreous hemorrhage, retinal detachment, and endophthalmitis. One case had infusion-fluid-related JSI, while four developed it because of injection of surgical adjuncts (drugs, PFCL, and dye). JSI developed in two cases when the vitreous cavity was filled with fluid, while it was air-filled in three cases. In four cases, the fluid migrated into subretinal space, necessitating further maneuvers following which the breaks healed, but were directly responsible for vision loss in two cases.Conclusion:JSI related IRBs are rare but may be directly responsible for vision loss if they impact the macula. The balance between jet stream velocity, its distance from the retinal surface, the intervening media (vitreous cavity), and retinal health play an important role. It can occur because of both infusion as well as injection jets. Precautions must be taken in cases vulnerable to complications with suggested modifications in the surgical technique. 相似文献