高脂血症大鼠红细胞扫描电镜观察

目的 :探讨高脂血症红细胞形态变化和临床意义。方法 :Wistar大鼠分为正常对照组 ( NC)和高脂血症组 ( HL,喂饲高脂饲料 ) ,利用扫描电镜观察红细胞形态改变并计数分类。结果 :与 NC组比较 ,HL组的正常红细胞百分比由 76.4 %减少到 4 5.7%、棘型红细胞、球口型红细胞、靶型红细胞分别由4 %、2 .2 %、1.5%增加到 17.3%、10 .4 %、5.8% ,嵴型和其它异型红细胞也略有增加。结论 :高脂血症的异型红细胞明显增加。     

Study of the mechanism of essential garlic oil inhibiting lnterleukin-1 α-induced monocyte adhesion to endothelial cells

Objective  

To observe the effects of essential garlic oil (EGO) on vascular cell adhesive molecule-1 (VCAM-1) expression of endothelial cells and monocyte-endothelial cell adhesion rate induced by interleukin-l_α(IL-l_α).     

Study of therapeutic mechanism of acupuncture in treating bronchial asthma

Ｉｔｈａｓｂｅｅｎｃｏｎｓｉｄｅｒｅｄｂｙｍｏｄｅｒｎｍｅｄｉｃｉｎｅｔｈａｔｂｒｏｎｃｈｉａｌａｓｔｈｍａｉｓａｃｈｒｏｎｉｃａｉｒｗａｙａｌｌｅｒｇｉｃｉｎｆｌａｍｍａｔｉｏｎ（ＡＡＩ）ｗｈｉｃｈｉｓｔｈｅｍａｊｏｒｆａｃｔｏｒｔｈａｔｉｎｄｕｃｅｓｒｅｖｅｒｓｉｂｌｅａｉｒｗａｙｖｅｎｔｉｌａｔｉｎｇｄｉｓｔｕｒｂａｎｃｅａｎｄｂｒｏｎｃｈｉａｌｈｙｐｅｒ ｒｅ ｓｐｏｎｓｉｖｅｎｅｓｓ（ＢＨＲ）ｉｎａｓｔｈｍａｔｉｃｐａｔｉｅｎｔｓ,ａｓｗｅｌｌａｓａｃｏｒｒｅｌａｔｉｏｎｂｅｔｗｅｅｎｔ…     

止泻颗粒剂治疗小儿消化不良性肠炎136例

运用止泻颗粒剂与思密达作对照治疗小儿消化不良性肠炎,治疗组136例,对照组80例,2组总有效率分别为95．5％,37．5％,疗效比较具有显著性差异,P＜0．01。     

脑梗死患者血ET和TNF-α含量变化的研究

目的　研究脑梗死 (CI)患者发病初期及第 3周血中 ET和 TNF- α含量变化。方法　用放射免疫分析法检测 6 8例 CI患者发病 2～ 5天和病程第 3周初及 36例对照组血中 ET和 TNF- α水平。结果　 CI发病初期两种因子均显著升高 ,CI各组间及与对照组间有显著性差异 (P<0 .0 1) ;病程第 3周比病初血中含量明显下降 (P<0 .0 1) ,ET在重型组和大灶组仍明显高于对照组 (P<0 .0 1) ,TNF- α在 CI各组间及中重型 /大中灶组与对照组间仍具显著性差异。结论　 CI患者发病初期血 ET和 TNF- α水平显著升高 ,在此时检测其含量高低 ,有助于临床诊断、判断病情及推测预后     

激光焊接对金瓷结合的影响

OBJECTIVE: This study was aimed to investigate the bonding effect of laser welding on ceramic fused to metal. METHODS: Ten laser welded CW-PA ceramo-alloy rods were fused with porcelain at fusion zone. The porcelain-metal bond strength was measured with pull-through test. SEM examination and EDAX analysis were performed. Ten non-welded CW-PA ceramo-alloy pull-rod plates were used as comparison. RESULTS: The results showed that the bond strength of laser welded sample was 41.32 +/- 6.69 MPa, approaching to 45.71 +/- 9.98 MPa of the non-welded sample (P > 0.05). The microscope displayed the interface compacted union of the two phase boundary. There was no change in the elements and their ratio at the fusion zone. CONCLUSION: These results indicate that laser welding does not affect ceramic fused to metal.     

口腔链球丙酮酸氧化酶的克隆和序列分析

目的 阐明血链球菌产生过氧化氢及其调节的分子机理。方法 根据已知的肺炎链球菌丙酮酸氧化酶基因（spxB）序列设计PCR引物,扩增血链球菌ATCC10557的丙酮酸氧化酶基因,以pUC18及M13mp18、M13mp19为载体进行克隆和亚克隆,并进行序列分析。结果 成功地从血链球菌ATCC10557扩增出丙酮酸氧化酶基因,获得该基因的全部序列（1788bp),具有完整的开放读框,能编码591个氨基酸的多肽。结论 血链球菌丙酮酸氧化酶基因的克隆和序列分析,为进一步研究调节血链球菌产生过氧化氢的分子机理打下了基础。     

尖锐湿疣Fas、bcl—2、Ki—67的表达与细胞凋亡的关系

OBJECTIVE: This study inquired into the significance and relationship of apoptosis to the regulation and proliferation of condyloma acuminatum(CA). METHODS: Apoptotic cells were detected in situ by terminal deoxynucleotidyl transferase-mediated-dUTP nick end labeling (TUNEL). The detection of Fas, bcl-2 and Ki-67 expression was performed using immunohistochemical staining in 28 specimens of CA. RESULTS: Apoptotic cells were found in 24 cases (85.7%) in keratinocytes. All of the in 28 cases(100%) had Fas and Ki-67 positive expressions, but only 8 cases (28.6%) had bcl-2 mild or moderate expression. The disease severity (serious, moderate and mild) groups did not significantly differ in apoptotic index (AI), Fas, bcl-2 and Ki-67 positive expression (P > 0.05). There was positive correlation between AI and Fas(r = 0.866, P = 0.000). bcl-2 and Ki-67 were negatively correlated with AI (r = -0.416, P = 0.018; r = -0.475, P = 0.006). CONCLUSION: It is suggested that apoptosis in keratinocytes may play an important role in inhibiting the proliferation of virus, that Fas may be an upregulative factor and bcl-2 may be an inhibition factor to apoptosis, and that excessive Ki-67 expression may be associated with the acceleration of cell cycle.