全文获取类型
收费全文 | 637篇 |
免费 | 54篇 |
国内免费 | 7篇 |
专业分类
耳鼻咽喉 | 1篇 |
儿科学 | 32篇 |
妇产科学 | 4篇 |
基础医学 | 48篇 |
口腔科学 | 32篇 |
临床医学 | 60篇 |
内科学 | 147篇 |
皮肤病学 | 20篇 |
神经病学 | 15篇 |
特种医学 | 138篇 |
外科学 | 42篇 |
综合类 | 76篇 |
预防医学 | 17篇 |
药学 | 37篇 |
1篇 | |
肿瘤学 | 28篇 |
出版年
2022年 | 3篇 |
2021年 | 3篇 |
2020年 | 1篇 |
2019年 | 4篇 |
2018年 | 11篇 |
2017年 | 7篇 |
2016年 | 10篇 |
2015年 | 13篇 |
2014年 | 17篇 |
2013年 | 15篇 |
2012年 | 12篇 |
2011年 | 8篇 |
2010年 | 20篇 |
2009年 | 28篇 |
2008年 | 13篇 |
2007年 | 14篇 |
2006年 | 33篇 |
2005年 | 8篇 |
2004年 | 11篇 |
2003年 | 17篇 |
2002年 | 8篇 |
2001年 | 9篇 |
2000年 | 6篇 |
1999年 | 7篇 |
1998年 | 30篇 |
1997年 | 50篇 |
1996年 | 45篇 |
1995年 | 33篇 |
1994年 | 34篇 |
1993年 | 36篇 |
1992年 | 19篇 |
1991年 | 9篇 |
1990年 | 12篇 |
1989年 | 13篇 |
1988年 | 17篇 |
1987年 | 9篇 |
1986年 | 6篇 |
1985年 | 8篇 |
1984年 | 9篇 |
1983年 | 11篇 |
1982年 | 16篇 |
1981年 | 14篇 |
1980年 | 8篇 |
1979年 | 5篇 |
1978年 | 4篇 |
1977年 | 6篇 |
1976年 | 15篇 |
1975年 | 9篇 |
1973年 | 1篇 |
1971年 | 1篇 |
排序方式: 共有698条查询结果,搜索用时 7 毫秒
91.
92.
94.
95.
Renal localization of gallium-67 citrate 总被引:1,自引:0,他引:1
96.
97.
98.
99.
Grüntzig balloon catheters were used to dilate ten esophageal strictures in eight infants and children. Five infants who had anastomotic strictures following esophageal atresia repair gained complete resolution of their strictures, usually after one or two dilatations. Three older children who had strictures following esophageal re-operation or reconstruction required longer courses of dilatations to achieve consistent esophageal patency. The technique failed in two chronic strictures of two and one-half and nine years' duration. Balloon catheter dilatation, begun in the early postoperative period, is a safe, effective method for dilating esophageal strictures. 相似文献
100.
GCS DOMINGUEZ RS COSTA M DANTAS T KIMACHI CR PIUCI TM COIMBRA 《Nephrology (Carlton, Vic.)》1998,4(1-2):31-35
SUMMARY: Transforming growth factor-β (TGF-β) has been considered the principal cytokine involved in the pathogenesis of renal fibrosis. In the present study, we evaluated TGF-β activity in occasional samples from 22 normal individuals and 29 patients (11 with focal glomerulosclerosis, 11 with membranous nephropathy, five with Berger disease, one with type I membranoproliferative glomerulonephritis and one with postinfectious glomerulonephritis) using a CCL-64 mink lung cell growth inhibition assay.
A significantly increased urinary TGF-β activity (reported in relation to urine creatinine, Ucreat, and median) was observed in patients with glomerulonephritis compared with normal individuals ( P <0.01). the patients with Berger disease [median (Md) = 9.96/10 μg Ucreat.], membranous glomerulonephritis (Md = 7.23/10 μg Ucreat.) and focal glomerulosclerosis (Md = 16.6/10 μg Ucreat.) showed higher urinary TGF-β than normal individuals (Md = 1.09/10 μg Ucreat.) ( P <0.01). We found a positive correlation between the TGF-β activity in the urine of these patients and the incidence of segmental glomerulosclerosis ( r = 0.45, P <0.05) and their plasma creatinine levels ( r = 0.87, P <0.01). A negative correlation was observed between the TGF-β activity in the urine of these patients and their creatinine clearance ( r =−0.75, P <0.01).
Our data suggest that measurement of urinary TGF-β activity could be a useful non-invasive procedure for the evaluation of renal TGF-β production, permitting the assessment of prognosis and the evaluation of therapeutic efficacy in patients with renal disease. 相似文献
A significantly increased urinary TGF-β activity (reported in relation to urine creatinine, Ucreat, and median) was observed in patients with glomerulonephritis compared with normal individuals ( P <0.01). the patients with Berger disease [median (Md) = 9.96/10 μg Ucreat.], membranous glomerulonephritis (Md = 7.23/10 μg Ucreat.) and focal glomerulosclerosis (Md = 16.6/10 μg Ucreat.) showed higher urinary TGF-β than normal individuals (Md = 1.09/10 μg Ucreat.) ( P <0.01). We found a positive correlation between the TGF-β activity in the urine of these patients and the incidence of segmental glomerulosclerosis ( r = 0.45, P <0.05) and their plasma creatinine levels ( r = 0.87, P <0.01). A negative correlation was observed between the TGF-β activity in the urine of these patients and their creatinine clearance ( r =−0.75, P <0.01).
Our data suggest that measurement of urinary TGF-β activity could be a useful non-invasive procedure for the evaluation of renal TGF-β production, permitting the assessment of prognosis and the evaluation of therapeutic efficacy in patients with renal disease. 相似文献