全文获取类型
收费全文 | 828篇 |
免费 | 28篇 |
国内免费 | 2篇 |
专业分类
耳鼻咽喉 | 4篇 |
儿科学 | 29篇 |
妇产科学 | 7篇 |
基础医学 | 81篇 |
口腔科学 | 11篇 |
临床医学 | 53篇 |
内科学 | 142篇 |
皮肤病学 | 39篇 |
神经病学 | 91篇 |
特种医学 | 73篇 |
外科学 | 117篇 |
综合类 | 58篇 |
一般理论 | 1篇 |
预防医学 | 20篇 |
眼科学 | 7篇 |
药学 | 47篇 |
中国医学 | 1篇 |
肿瘤学 | 77篇 |
出版年
2023年 | 17篇 |
2022年 | 18篇 |
2021年 | 27篇 |
2020年 | 19篇 |
2019年 | 22篇 |
2018年 | 19篇 |
2017年 | 9篇 |
2016年 | 17篇 |
2015年 | 22篇 |
2014年 | 21篇 |
2013年 | 40篇 |
2012年 | 47篇 |
2011年 | 67篇 |
2010年 | 27篇 |
2009年 | 34篇 |
2008年 | 38篇 |
2007年 | 47篇 |
2006年 | 29篇 |
2005年 | 28篇 |
2004年 | 18篇 |
2003年 | 14篇 |
2002年 | 25篇 |
2001年 | 30篇 |
2000年 | 21篇 |
1999年 | 17篇 |
1998年 | 13篇 |
1997年 | 9篇 |
1996年 | 15篇 |
1995年 | 13篇 |
1994年 | 16篇 |
1993年 | 4篇 |
1992年 | 8篇 |
1991年 | 5篇 |
1990年 | 4篇 |
1989年 | 7篇 |
1988年 | 6篇 |
1986年 | 5篇 |
1985年 | 7篇 |
1984年 | 7篇 |
1983年 | 9篇 |
1982年 | 10篇 |
1980年 | 6篇 |
1979年 | 5篇 |
1978年 | 7篇 |
1977年 | 5篇 |
1976年 | 3篇 |
1972年 | 3篇 |
1971年 | 3篇 |
1970年 | 3篇 |
1969年 | 3篇 |
排序方式: 共有858条查询结果,搜索用时 15 毫秒
21.
22.
23.
Ilias Nikolakopoulos MD James W. Choi MD Khaldoon Alaswad MD Jaikirshan J. Khatri MD Oleg Krestyaninov MD Dmitrii Khelimskii MD Robert W. Yeh MD PhD Farouc A. Jaffer MD PhD Catalin Toma MD Mitul Patel MD Ehtisham Mahmud MD Nicholas J. Lembo MD Manish Parikh MD Ajay J. Kirtane MD SM Ziad A. Ali MD Fotis Gkargkoulas MD Barry Uretsky MD Abdul M. Sheikh MD Evangelia Vemmou MD Iosif Xenogiannis MD Bavana V. Rangan BDS MPH Santiago Garcia MD Shuaib Abdullah MD Subhash Banerjee MD M. Nicholas Burke MD Emmanouil S. Brilakis MD PhD Dimitri Karmpaliotis MD PhD 《Catheterization and cardiovascular interventions》2021,97(4):658-667
24.
Omar M. Abdelfattah MD Anas M. Saad MD Nicholas Kassis MD Shashank Shekhar MD Toshiaki Isogai MD MPH Mohamed M. Gad MD Keerat R. Ahuja MD Essa Hariri MD Manpreet Kaur MD Medhat Farwati MD Jaikirshan Khatri MD Amar Krishnaswamy MD Samir R. Kapadia MD 《Catheterization and cardiovascular interventions》2021,98(7):1317-1331
25.
Major histocompatibility complex haplotype studies in Ashkenazi Jewish patients with pemphigus vulgaris. 下载免费PDF全文
A R Ahmed E J Yunis K Khatri R Wagner G Notani Z Awdeh C A Alper 《Proceedings of the National Academy of Sciences of the United States of America》1990,87(19):7658-7662
Of 26 Ashkenazi Jewish patients with pemphigus vulgaris, 24 (92.3%) carried the major histocompatibility complex (MHC) class II alleles HLA-DR4, DQw3, of which all were of the subtype DR4, DQw8. From studies of the patients and their families, haplotypes were defined. It was found that, of the patients who carried HLA-DR4, DQw8, 75% carried one or the other (and in one case, both) of two haplotypes [HLA-B38, SC21, DR4] or HLA-B35, SC31, DR4. The former is a known extended haplotype among normal Jews, with a frequency of 0.102, and the latter may also be an extended haplotype in this ethnic group, with a frequency of 0.017 among normal haplotypes from Jews. Of the remaining DR4-positive patients, all but one had a presumed D-region segment (defined as SC21, DR4, DQw8 or SC31, DR4, DQw8 with variable HLA-B) of these haplotypes. Only one patient had DR4, DQw8 without any other markers of the extended haplotypes. The number of homozygotes and heterozygotes for DR4, DQw8 was consistent with dominant but not recessive (P less than 0.01) inheritance of a class II or a class II-linked susceptibility gene for the disease. Since the disease is entirely attributable to the presence of an antibody to an intraepidermal intercellular cement substance, it is likely that the class II susceptibility gene (on [HLA-B38, SC21, DR4, DQw8], HLA-B35, SC31, DR4, DQw8, or their segments, in Jewish patients) controls the production of the antibody as a dominantly expressed immune response gene. 相似文献
26.
Alterations of the arginine metabolome in asthma 总被引:1,自引:0,他引:1
Lara A Khatri SB Wang Z Comhair SA Xu W Dweik RA Bodine M Levison BS Hammel J Bleecker E Busse W Calhoun WJ Castro M Chung KF Curran-Everett D Gaston B Israel E Jarjour N Moore W Peters SP Teague WG Wenzel S Hazen SL Erzurum SC;National Heart Lung Blood Institute's Severe Asthma Research Program 《American journal of respiratory and critical care medicine》2008,178(7):673-681
27.
In vivo release and turnover of secreted platelet antiheparin proteins in rhesus monkey (Macaca mulatta) 总被引:1,自引:0,他引:1
Musial J; Niewiarowski S; Edmunds LH Jr; Addonizio VP Jr; Nicolaou KC; Colman RW 《Blood》1980,56(4):596-607
Human and rhesus monkey platelets secrete at least two antiheparin proteins: platelet factor 4 (PF4) and low affinity platelet factor 4 (LA-PF4). Neither of these proteins showed species-related antigenic differences. As determined by radioimmunoassay, the levels of PF4 and LA-PF4 antigen per 10(9) monkey platelets amounted to 10.7 and 20.3 microgram, respectively. One milliliter of monkey plasma prepared from blood collected into an anticoagulant composed of EDTA, prostaglandin E1, and theophylline solution contained 22.4 ng LA-PF4 and 8.0 ng PF4. Concentrations of these two platelet-specific proteins in monkeys closely resembled levels found in human platelets and plasma. Infusion of prostacyclin (PGI2) (100 or 300 ng/kg/min) into monkeys for 15 min resulted in a significant decrease of plasma levels of LA-PF4 antigen and of PF4 by 40%--60% (p < 0.0001). This decrease was related to the inhibitory effect of PGI2 on the secretion of platelets stimulated by a catheter or by venipuncture. Longer infusion of PGI2 did not produce further significant change. The supernate obtained after aggregation of human platelets stimulated by thrombin was injected into monkeys receiving PGI2 infusion. The disappearance of LA-PF4 antigen in monkey plasma followed a biphasic exponential curve with half-lives for the fast and slow components of 8.4 and 63 min. PF4 disappeared faster but followed the same pattern (half-lives for the fast and slow component of 2.1 and 70 min). Analysis of the experimental data suggests that the low levels of secreted platelet proteins in monkey plasma are related to their minimal in vivo release and to their rapid clearance. 相似文献
28.
29.
30.
Metal and metal oxide nanoparticles are being used in different industries now‐a‐days leading to their unavoidable exposure to humans and animals. In the present study, toxicological testing was done using nanoparticles of copper oxide, cerium oxide and their mixture (1:1 ratio) on zebra fish embryos and THP‐1 cell line. Zebrafish embryos were exposed to 0.01 μg/ml to 50 μg/ml concentrations of dispersed nanoparticles using a 96 well plate and their effects were studied at different hours post fertilization (hpf) i.e. 0 hpf, 24 hpf, 48 hpf, 72 hpf and 96 hpf respectively. Results showed that copper oxide nanoparticles has drastic effects on the morphology and physiology of zebra fish whereas cerium oxide nanoparticles and mixture of these nanoparticles did not show much of the effects. Comparable results were obtained from in vitro study using human monocyte cell line (THP‐1). It is concluded that these nanoparticles may cause toxicological effects to humans and environment. 相似文献