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681.
682.
Maman D Greenwald D Kreniske J Royston A Powers S Bauer J 《Annals of plastic surgery》2012,68(2):190-193
Incisional hernias develop in 2% to 11% of patients who undergo laparotomy. Prosthetic mesh repair provides more strength, tension-free closure, and decreased recurrence rates as compared to primary tissue repairs. Complications-fistula formation, adhesions, skin erosion, and seroma/abscess formation-however, include increased rates of infection, sometimes requiring complete mesh removal. The Rives-Stoppa repair for complex incisional hernias confers the benefits of prosthetic repair and lower recurrence rates, but decreases certain complications by preventing direct mesh contact with the bowel. A total of 89 consecutive patients (mean age, 58.1) underwent a modified Rives-Stoppa repair for purposes of this review, all the patients who lost to follow-up before 6 months postoperatively were excluded from the study. Of the remaining 59 patients, 32.2% (n = 19) had expanded polytetrafluoroethylene mesh, and 67.8% (n = 40) had polypropylene mesh. Average range of follow-up was 40.0 months. Hernia recurred in 1 patient (1.7%). Infection requiring explantation of the prosthesis occurred in 3 patients (5.1%). The Rives-Stoppa repair is reportedly the best open technique for complex incisional hernias with comparatively lower recurrence rates. Additionally, patients with inflammatory bowel disease (64.4% of our series), who often require later reoperation for their primary disease, may benefit from this technique of herniorrhaphy where no interface exists between intrabdominal contents and the prosthesis. This lack of interface decreases intrabdominal adhesions and facilitates re-entry if future surgery is needed for inflammatory bowel disease. 相似文献
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684.
Celine Barnadas Nicolas Senn Jonah Iga Lincoln Timinao Sarah Javati Elisheba Malau Patricia Rarau John C. Reeder Peter Siba Harin Karunajeewa Peter A. Zimmerman Timothy M. Davis Ivo Mueller 《Antimicrobial agents and chemotherapy》2014,58(11):6958-6961
Intermittent preventive treatment of infants (IPTi) reduces early childhood malaria-related morbidity. While genotypic drug resistance markers have proven useful in predicting the efficacy of antimalarial drugs in case management, there are few equivalent data relating to their protective efficacy when used as IPTi. The present data from an IPTi trial in Papua New Guinea demonstrate how these markers can predict protective efficacy of IPTi for both Plasmodium falciparum and Plasmodium vivax. 相似文献
685.
Ezekiel Uba Nwose Phillip Taderera Bwititi Otovwe Agofure Echinei Jacob Oshionwu Ekenechukwu Esther Young Eferhire Aganbi Solomon Ekwuweokwuenu Egwenu Helen Egoyibo Chime Fortunatus Darius Gbeinbo Alex Odufu John Nwakaego Okuzor Azuka Okuleye Kennedy Aninze Innocent Chuks Onyia Euzebus Chinonye Ezugwu Eunice Obiajuru Igumbor Ifeoma Isabel Ulasi 《World Journal of Meta-Analysis》2021,9(6):543-556
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687.
Ofer N. Gofrit Igal Rabinovich Vladimir Yutkin Dov Pode Mordechai Duvdevani Ezekiel H. Landau Guy Hidas S. Nahum Goldberg 《Urologic oncology》2018,36(11):498.e9-498.e13
Introduction
Postoperative surveillance protocols after nephrectomy for kidney cancer include periodic computed tomography (CT) scans of the chest and abdomen. A single study exposes the patient to 21 mSv (equivalent to 7-year exposure to natural background radiation). The objective of this study was to evaluate the hypothesis that an abbreviated CT protocol restricted to the chest and upper abdomen (i.e., to the level of the intervertebral disk L3–L4) is sufficient for routine postnephrectomy follow-up as it detects most tumor recurrence with lower radiation exposure.Methods
We identified 493 patients treated with radical or partial nephrectomy for localized kidney cancer and followed with periodic CT scans of the chest and abdomen for prolonged periods. The frequency and location of cancer recurrence were documented. The ratio of infield recurrence for the complete chest, and abdomen and for the abbreviated protocol was recorded. The decrease in radiation exposure was calculated.Results
At a median follow up of 96 months, 82 patients (16.6%) developed recurrence. The frequent sites of recurrence were the lungs (53), the bones (9), and local recurrence (22). Complete chest and abdominal CT identified 78 of the recurrences (95%) and the abbreviated protocol identifying all but one of these (94%). The abbreviated protocol exposed the patient to 48% (standard deviation 4.3%) less radiation compared to the full protocol.Conclusions
Using an abbreviated CT protocol that includes the chest and upper abdomen for surveillance after surgery of localized kidney cancer decreases radiation exposure by half with only a minor decrease in the sensitivity of the examination. 相似文献688.
689.
Christine M. Durand Wanying Zhang Diane M. Brown Sile Yu Niraj Desai Andrew D. Redd Serena M. Bagnasco Fizza F. Naqvi Shanti Seaman Brianna L. Doby Darin Ostrander Mary Grace Bowring Yolanda Eby Reinaldo E. Fernandez Rachel Friedman-Moraco Nicole Turgeon Peter Stock Peter Chin-Hong Shikha Mehta Valentina Stosor Catherine B. Small Gaurav Gupta Sapna A. Mehta Cameron R. Wolfe Jennifer Husson Alexander Gilbert Matthew Cooper Oluwafisayo Adebiyi Avinash Agarwal Elmi Muller Thomas C. Quinn Jonah Odim Shirish Huprikar Sander Florman Allan B. Massie Aaron A. R. Tobian Dorry L. Segev the HOPE in Action Investigators 《American journal of transplantation》2021,21(5):1754-1764
HIV-positive donor to HIV-positive recipient (HIV D+/R+) transplantation is permitted in the United States under the HIV Organ Policy Equity Act. To explore safety and the risk attributable to an HIV+ donor, we performed a prospective multicenter pilot study comparing HIV D+/R+ vs HIV-negative donor to HIV+ recipient (HIV D−/R+) kidney transplantation (KT). From 3/2016 to 7/2019 at 14 centers, there were 75 HIV+ KTs: 25 D+ and 50 D− (22 recipients from D− with false positive HIV tests). Median follow-up was 1.7 years. There were no deaths nor differences in 1-year graft survival (91% D+ vs 92% D−, P = .9), 1-year mean estimated glomerular filtration rate (63 mL/min D+ vs 57 mL/min D−, P = .31), HIV breakthrough (4% D+ vs 6% D−, P > .99), infectious hospitalizations (28% vs 26%, P = .85), or opportunistic infections (16% vs 12%, P = .72). One-year rejection was higher for D+ recipients (50% vs 29%, HR: 1.83, 95% CI 0.84-3.95, P = .13) but did not reach statistical significance; rejection was lower with lymphocyte-depleting induction (21% vs 44%, HR: 0.33, 95% CI 0.21-0.87, P = .03). In this multicenter pilot study directly comparing HIV D+/R+ with HIV D−/R+ KT, overall transplant and HIV outcomes were excellent; a trend toward higher rejection with D+ raises concerns that merit further investigation. 相似文献
690.
Donald F Ezekiel 《Clinical & experimental optometry》2000,83(6):337-338