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91.
目的:介绍准分子激光冠状动脉成形术(ELCA)治疗冠状动脉狭窄的临床应用经验。材料和方法:10例冠心病患者作冠状动脉造影确认有14支冠状动脉狭窄(狭窄率70%~75%者5支,90%~100%者9支)。全部病例均作ELCA手术。ELCA采用脉冲间期为180-220msec,光导纤维直径为1.3~1.6mm,能量密度14.5~21.0mJ,激光频率为20Hz。ELCA术后辅以球囊扩张血管成形术(PTCA)。结果:9例13支狭窄动脉中,9支狭窄率>90%者,作ELCA+PTCA成功,其中7支动脉狭窄率减至15%以下,2支减至40%~45%,1例因术中导丝头断裂,失败。成功的9支动脉术后冠状动脉造影示:内膜光滑4支,毛糙3支,夹层动脉瘤1支(2月后随访消失),术中出现血栓1支。术后6个月内造影随访,3例动脉再度狭窄。结论:准分子激光冠状动脉成形术可用于PTCA难以成功的有钙化硬斑、挟窄段较长(>2.0cm)和闭塞的冠状动脉,安全有效。但它并不能避免术后再狭窄的发生。 相似文献
92.
广州家禽、家畜批发市场六种动物隐孢子虫感染情况的调查 总被引:4,自引:1,他引:3
目的调查广州家禽、家畜批发市场兔、鸭(含雏鸭)、羊、鸡、狗、鸽6种动物的隐孢子虫感染情况。方法取上述动物的粪便292份,用金胺-酚-改良抗酸复染法染色,镜检卵囊。结果检查的6种动物均发现有隐孢子虫感染,自然感染率分别为:64.1%,54.3%(45.0%),21.7%,20.6%,20.0%,14.6%。结论广州家禽、家畜批发市场6种动物存在隐孢子虫感染。 相似文献
93.
94.
受染伯氏疟原虫ANKA株小鼠ig三吡萘啶游离碱11mg/kg给药后1h可见少数滋养体复合物层次增多且断裂,皱缩,并出现间隙,食物泡融合增大,2h后进一步加剧,且疟原虫髓样物也增多,线粒体肿胀,4h后出现变化的原虫更明显增多,8h后绝大多数滋养体结构多已瓦解,仅留上膜残体及大小不等的空泡,总之,其超微结构的变化与咯萘啶作用甚为相似。 相似文献
95.
肝动脉化疗,栓塞与肝静脉暂时闭塞治疗肝癌 总被引:1,自引:0,他引:1
本文报道在10例肝癌患者中运用肝静脉暂时闭塞和肝动脉内灌注化疗、栓塞的方法治疗取得较好疗效。7例甲胎蛋白阳性患者5例下降大于50%,2例转阴。4例肿瘤缩小>50%。2例合并肝动-静脉瘘者成功实行碘油栓塞,1例经治疗后肝动-静脉瘘消失。对肝功能的影响与普通介入治疗相同。消化道反应相对较轻。并可提高肿瘤局部药物浓度,延长药物作用时间。配合肝段动脉或靶血管的插管可进一步提高疗效,减少并发症。 相似文献
96.
Salahudeen Abdulla K.; Wang Chunyou; Bigler Steven A.; Dai Zhongyi; Tachikawa Hiroyasu 《Nephrology, dialysis, transplantation》1996,11(4):635-642
BACKGROUND AND PURPOSE.: Heme-proteins, besides causing renal tubular obstruction, maycontribute to rhabdomyolysis-induced renal injury through aheme-iron-mediated lipid peroxidation process. In the presentstudy, we compared the combined therapy of a lipid peroxidationinhibitor, 21-aminosteroid (21-AS) and fluid-alkaline-mannitol(FAM) diuresis with either of them alone to determine the efficacyof the combination therapy and to delineate the roles of lipidperoxidation and cast formation. METHODS AND RESULTS.: Employing Raman spectroscopy, we confirmed in vitro the abilityof 21-AS to inhibit iron-induced fatty acid peroxidation. 21-ASwas then administered to rats developing renal failure fromglycerol-induced rhabdomyolysis. Although 21-AS inhibited rhabdomyolysis-inducedplasma and renal lipid peroxidation, renal protection was incomplete.Administration of FAM to inhibit cast formation afforded a betterrenal protection. However, when these therapies were combinedto inhibit both lipid peroxidation and cast formation, therewas a synergistic renal functional protection. This was accompaniedby a maximum inhibition of renal and plasma lipid peroxidation,as well as, renal tubular necrosis and cast formation. Comparedto combination therapy, FAM therapy alone, despite identicalvolume, was accompanied by a higher tubular necrosis and castformation. CONCLUSIONS.: That combining a lipid peroxidation inhibitor with fluid-alkalinediuresis in rhabdomyolysis further lowers renal lipid peroxidation,tubular necrosis and cast formation and synergistically limitsrenal dysfunction (i) supports a role for lipid peroxidationin the pathophysiology of rhabdomyolysis ARF, (ii) underscoresthe role of intratubular heme retention, a cause for tubularobstruction as well a source for prodigious amount of iron,likely involved in the lipid peroxidation, and (iii) raisesthe possibility of interactions between non-oxidant and oxidantmechanisms. 相似文献
97.
目的 调查农村5岁以下儿童肺炎死亡相关的社会危险因素.方法1995年11月—1997年2月在湖北恩施和建始两个贫困地区对5岁以下儿童肺炎死亡的危险因素进行病例—对照研究,死亡病例组226例,肺炎对照组 452例.结果 引起儿童肺炎死亡的社会-经济危险因素有:家庭的人均年收入少于 450元、母亲没有立即带孩子看病的理由是没钱看病或交通不便、家中曾有过一个孩子死亡、家长和村医生的文化程度低、父亲的职业是农民、居室内有火炉、母亲对疾病的认识不够、医生的专业培训不足等.结论 除生物相关因素外,社会危险因素同样是农村5岁以下儿童肺炎死亡的重要因素.它们中某些因素是可以借助对父母的健康教育和急性呼吸道感染病例标准管理而得到控制. 相似文献
98.
99.
THE COMPUTERIZED GAIT ANALYSIS SYSTEM AND THREE DIMENSIONAL ANALYSIS OF FOOT-GROUND REACTION FORCES DURING LEVEL WALKING 总被引:1,自引:0,他引:1
A S9-2 computerized gait analysis system developed by us is reported. The advantages of the system are: synchronous measurement of the forces, angles and time parameters; high efficiency, accuracy and good repeatability; low cost and easy to operate. A three dimensional analysis of the foot-ground reaction forces of 41 normal subjects during level walking was carried out by the S9-2 system and a series of normal values of parameters and characteristic curves were obtained. The mechanism of formation of the parameters and curves and the sex influence were investigated and discussed. In old subject, before the development of "cautious gait", most values of the parameters did not differ significantly from those of the young subjects, except that the centre of gravity of the body crossing the hip earlier with a slight decrease in the medio-lateral balance capacity. 相似文献
100.
Poorly differentiated adenocarcinoma of the nasopharynx is not rare. It comprises 5% of all nasopharyngeal carcinomas. In this paper, specimens of 41 cases of poorly differentiated adenocarcinoma of the nasopharynx were studied. The microscopic findings have the tendency to form glandular or duct-like structures, or a specific "cerebriform" appearance, AB-PAS stain was positive. In addition to the common features of adenocarcinoma (cancer cells vary in size, with large, round central nuclei, enlarged conspicuous nucleoli), a specific feature that the nuclei of cancer cells were 1-2 times larger than those of normal cells was seen in smear. Electron microscopic observation revealed that the cytoplasm of the cancer cells contained numerous mitochondria, RER, developed Golgi apparatus and some secretory granules. Immunocytochemical studies proved that it was moderately positive for immunostain of low molecular weight keratin protein (K10,11), but was negative for keratin (K) it is different from poorly differentiated squamous cell carcinoma and vesicular nuclear cell carcinoma, of which were strongly positive or partially positive for keratin. The main points of differential diagnosis for these carcinomas are elucidated. 相似文献